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Results: 1 to 20 of 166

1.

Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia.

Wiestner A.

Blood. 2012 Dec 6;120(24):4684-91. doi: 10.1182/blood-2012-05-423194. Epub 2012 Aug 8. Review. Erratum in: Blood. 2013 Oct 24;122(17):3090.

PMID:
22875912
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia.

Wiestner A.

Hematology Am Soc Hematol Educ Program. 2012;2012:88-96. doi: 10.1182/asheducation-2012.1.88. Review. Erratum in: Hematology Am Soc Hematol Educ Program. 2013;2013:692.

PMID:
23233565
[PubMed - indexed for MEDLINE]
Free Article
3.

Targeted therapy in chronic lymphocytic leukemia: past, present, and future.

Danilov AV.

Clin Ther. 2013 Sep;35(9):1258-70. doi: 10.1016/j.clinthera.2013.08.004. Review.

PMID:
24054703
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia.

Burger JA.

Curr Hematol Malig Rep. 2012 Mar;7(1):26-33. doi: 10.1007/s11899-011-0104-z. Review.

PMID:
22105489
[PubMed - indexed for MEDLINE]
5.

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia.

Buchner M, Baer C, Prinz G, Dierks C, Burger M, Zenz T, Stilgenbauer S, Jumaa H, Veelken H, Zirlik K.

Blood. 2010 Jun 3;115(22):4497-506. doi: 10.1182/blood-2009-07-233692. Epub 2010 Mar 24.

PMID:
20335218
[PubMed - indexed for MEDLINE]
Free Article
6.

BCR signaling in chronic lymphocytic leukemia and related inhibitors currently in clinical studies.

Robak T, Robak P.

Int Rev Immunol. 2013 Aug;32(4):358-76. doi: 10.3109/08830185.2013.786711. Epub 2013 Apr 25. Review.

PMID:
23617253
[PubMed - indexed for MEDLINE]
7.

Targeting the B cell receptor pathway in chronic lymphocytic leukemia.

Davids MS, Brown JR.

Leuk Lymphoma. 2012 Dec;53(12):2362-70. doi: 10.3109/10428194.2012.695781. Review.

PMID:
22616724
[PubMed - indexed for MEDLINE]
8.

Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL.

Herman SE, Mustafa RZ, Gyamfi JA, Pittaluga S, Chang S, Chang B, Farooqui M, Wiestner A.

Blood. 2014 May 22;123(21):3286-95. doi: 10.1182/blood-2014-02-548610. Epub 2014 Mar 21.

PMID:
24659631
[PubMed - indexed for MEDLINE]
9.

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.

Quiroga MP, Balakrishnan K, Kurtova AV, Sivina M, Keating MJ, Wierda WG, Gandhi V, Burger JA.

Blood. 2009 Jul 30;114(5):1029-37. doi: 10.1182/blood-2009-03-212837. Epub 2009 Jun 2.

PMID:
19491390
[PubMed - indexed for MEDLINE]
Free Article
10.

Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro-survival microenvironmental signals.

McCaig AM, Cosimo E, Leach MT, Michie AM.

Br J Haematol. 2011 Apr;153(2):199-211. doi: 10.1111/j.1365-2141.2010.08507.x. Epub 2011 Feb 24.

PMID:
21352196
[PubMed - indexed for MEDLINE]
11.

Role of chemokines and their receptors in chronic lymphocytic leukemia: function in microenvironment and targeted therapy.

Han TT, Fan L, Li JY, Xu W.

Cancer Biol Ther. 2014 Jan;15(1):3-9. doi: 10.4161/cbt.26607. Epub 2013 Oct 22. Review.

PMID:
24149438
[PubMed - indexed for MEDLINE]
12.

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S, Flynn J, Jones J, Blum KA, Buggy JJ, Hamdy A, Johnson AJ, Byrd JC.

Blood. 2011 Jun 9;117(23):6287-96. doi: 10.1182/blood-2011-01-328484. Epub 2011 Mar 21.

PMID:
21422473
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Towards targeted therapy of chronic lymphocytic leukemia.

Niemann CU, Jones J, Wiestner A.

Adv Exp Med Biol. 2013;792:259-91. doi: 10.1007/978-1-4614-8051-8_12. Review.

PMID:
24014301
[PubMed - indexed for MEDLINE]
14.

Fostamatinib inhibits B-cell receptor signaling, cellular activation and tumor proliferation in patients with relapsed and refractory chronic lymphocytic leukemia.

Herman SE, Barr PM, McAuley EM, Liu D, Wiestner A, Friedberg JW.

Leukemia. 2013 Aug;27(8):1769-73. doi: 10.1038/leu.2013.37. Epub 2013 Feb 6. No abstract available.

PMID:
23385377
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape.

Burger JA.

Curr Opin Oncol. 2012 Nov;24(6):643-9. doi: 10.1097/CCO.0b013e3283589950. Review.

PMID:
22960555
[PubMed - indexed for MEDLINE]
16.

Ibrutinib (PCI-32765) in chronic lymphocytic leukemia.

Jain N, O'Brien S.

Hematol Oncol Clin North Am. 2013 Aug;27(4):851-60, x. doi: 10.1016/j.hoc.2013.01.006. Review.

PMID:
23915749
[PubMed - indexed for MEDLINE]
17.

Inhibitors of B-cell receptor signaling for patients with B-cell malignancies.

Choi MY, Kipps TJ.

Cancer J. 2012 Sep-Oct;18(5):404-10. Review.

PMID:
23006944
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

B-cell receptor inhibitors in chronic lymphocytic leukemia.

Flinn IW.

Clin Adv Hematol Oncol. 2011 Aug;9(8):605-6. No abstract available.

PMID:
22236988
[PubMed - indexed for MEDLINE]
19.

Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765).

Burger JA, Buggy JJ.

Leuk Lymphoma. 2013 Nov;54(11):2385-91. doi: 10.3109/10428194.2013.777837. Epub 2013 Aug 28. Review.

PMID:
23425038
[PubMed - indexed for MEDLINE]
20.

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo.

Ponader S, Chen SS, Buggy JJ, Balakrishnan K, Gandhi V, Wierda WG, Keating MJ, O'Brien S, Chiorazzi N, Burger JA.

Blood. 2012 Feb 2;119(5):1182-9. doi: 10.1182/blood-2011-10-386417. Epub 2011 Dec 16.

PMID:
22180443
[PubMed - indexed for MEDLINE]
Free Article

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