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Results: 1 to 20 of 90

1.

Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells.

Balakrishnan K, Aggarwal S, Wierda W, Gandhi V.

Leuk Lymphoma. 2013 May;54(5):1097-100. doi: 10.3109/10428194.2012.718344. Epub 2012 Sep 4. No abstract available.

PMID:
22866921
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

BH3 mimetic therapy: an emerging and promising approach to treating chronic lymphocytic leukemia.

Anderson MA, Huang DC, Roberts AW.

Leuk Lymphoma. 2013 May;54(5):909-11. doi: 10.3109/10428194.2013.769223. Epub 2013 Feb 1. No abstract available.

PMID:
23339446
[PubMed - indexed for MEDLINE]
3.

The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.

Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.

J Biol Chem. 2011 Mar 18;286(11):9382-92. doi: 10.1074/jbc.M110.203638. Epub 2010 Dec 9.

PMID:
21148306
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

BH3-mimetics- and cisplatin-induced cell death proceeds through different pathways depending on the availability of death-related cellular components.

Andreu-Fernández V, Genovés A, Messeguer A, Orzáez M, Sancho M, Pérez-Payá E.

PLoS One. 2013;8(2):e56881. doi: 10.1371/journal.pone.0056881. Epub 2013 Feb 21.

PMID:
23437261
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.

González-Gironès DM, Moncunill-Massaguer C, Iglesias-Serret D, Cosialls AM, Pérez-Perarnau A, Palmeri CM, Rubio-Patiño C, Villunger A, Pons G, Gil J.

Apoptosis. 2013 Aug;18(8):1008-16. doi: 10.1007/s10495-013-0850-6.

PMID:
23605481
[PubMed - indexed for MEDLINE]
6.
7.

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.

Gillissen B, Essmann F, Hemmati PG, Richter A, Richter A, Oztop I, Chinnadurai G, Dörken B, Daniel PT.

J Cell Biol. 2007 Nov 19;179(4):701-15.

PMID:
18025305
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.

Balakrishnan K, Wierda WG, Keating MJ, Gandhi V.

Blood. 2008 Sep 1;112(5):1971-80. doi: 10.1182/blood-2007-12-126946. Epub 2008 Jun 19.

PMID:
18566329
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).

Lindenboim L, Blacher E, Borner C, Stein R.

Cell Death Differ. 2010 Feb;17(2):346-59. doi: 10.1038/cdd.2009.145. Epub 2009 Oct 9.

PMID:
19816507
[PubMed - indexed for MEDLINE]
Free Article
10.

Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.

Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N.

Hepatology. 2011 Jul;54(1):240-51. doi: 10.1002/hep.24305. Epub 2011 Apr 11.

PMID:
21425311
[PubMed - indexed for MEDLINE]
11.

Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737.

Kojima K, Duvvuri S, Ruvolo V, Samaniego F, Younes A, Andreeff M.

Cancer. 2012 Feb 15;118(4):1023-31. doi: 10.1002/cncr.26360. Epub 2011 Jul 14.

PMID:
21761401
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.

Wang C, Youle RJ.

Oncogene. 2012 Jun 28;31(26):3177-89. doi: 10.1038/onc.2011.497. Epub 2011 Nov 7.

PMID:
22056880
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

BH3-only proteins Noxa, Bik, Bmf, and Bid activate Bax and Bak indirectly when studied in yeast model.

Gérecová G, Kopanicová J, Jaká P, Běhalová L, Juhásová B, Bhatia-Kiššová I, Forte M, Polčic P, Mentel M.

FEMS Yeast Res. 2013 Dec;13(8):747-54. doi: 10.1111/1567-1364.12074. Epub 2013 Sep 23.

PMID:
23991648
[PubMed - indexed for MEDLINE]
14.

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC.

J Biol Chem. 2008 Apr 11;283(15):9580-6. doi: 10.1074/jbc.M708426200. Epub 2008 Jan 4.

PMID:
18178565
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic.

Ghiotto F, Fais F, Tenca C, Tomati V, Morabito F, Casciaro S, Mumot A, Zoppoli G, Ciccone E, Parodi S, Bruno S.

Cancer Biol Ther. 2009 Feb;8(3):263-71. Epub 2009 Feb 17.

PMID:
19164937
[PubMed - indexed for MEDLINE]
Free Article
16.

Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.

Nakajima W, Tanaka N.

J Nippon Med Sch. 2007 Apr;74(2):148-57.

PMID:
17507791
[PubMed - indexed for MEDLINE]
Free Article
17.

Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1.

Du X, Youle RJ, FitzGerald DJ, Pastan I.

Mol Cell Biol. 2010 Jul;30(14):3444-52. doi: 10.1128/MCB.00813-09. Epub 2010 May 10.

PMID:
20457813
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.

Bellosillo B, Villamor N, López-Guillermo A, Marcé S, Bosch F, Campo E, Montserrat E, Colomer D.

Blood. 2002 Sep 1;100(5):1810-6.

PMID:
12176904
[PubMed - indexed for MEDLINE]
Free Article
19.

Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis.

Karlberg M, Ekoff M, Labi V, Strasser A, Huang D, Nilsson G.

Cell Death Dis. 2010 May 13;1:e43. doi: 10.1038/cddis.2010.20.

PMID:
21364649
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11649-54. Epub 2007 Jul 2.

PMID:
17606912
[PubMed - indexed for MEDLINE]
Free PMC Article

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