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Results: 1 to 20 of 116

1.

Close proximity to Igh is a contributing factor to AID-mediated translocations.

Rocha PP, Micsinai M, Kim JR, Hewitt SL, Souza PP, Trimarchi T, Strino F, Parisi F, Kluger Y, Skok JA.

Mol Cell. 2012 Sep 28;47(6):873-85. doi: 10.1016/j.molcel.2012.06.036. Epub 2012 Aug 2.

PMID:
22864115
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.

White CA, Seth Hawkins J, Pone EJ, Yu ES, Al-Qahtani A, Mai T, Zan H, Casali P.

Autoimmunity. 2011 Dec;44(8):585-98. doi: 10.3109/08916934.2011.577128. Epub 2011 May 18. Erratum in: Autoimmunity. 2011 Dec;44(8):664.

PMID:
21585311
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC.

Nature. 2006 Mar 2;440(7080):105-9. Epub 2006 Jan 8.

PMID:
16400328
[PubMed - indexed for MEDLINE]
4.

AID and Igh switch region-Myc chromosomal translocations.

Unniraman S, Schatz DG.

DNA Repair (Amst). 2006 Sep 8;5(9-10):1259-64. Epub 2006 Jun 19. Review.

PMID:
16784901
[PubMed - indexed for MEDLINE]
5.

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC.

Cell. 2008 Dec 12;135(6):1028-38. doi: 10.1016/j.cell.2008.09.062.

PMID:
19070574
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD.

J Immunol. 2012 Sep 1;189(5):2374-82. doi: 10.4049/jimmunol.1200414. Epub 2012 Jul 23.

PMID:
22826323
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mechanisms promoting translocations in editing and switching peripheral B cells.

Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW.

Nature. 2009 Jul 9;460(7252):231-6. doi: 10.1038/nature08159.

PMID:
19587764
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.

Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, Reina San-Martin B, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC.

Immunity. 2008 May;28(5):630-8. doi: 10.1016/j.immuni.2008.04.002. Epub 2008 May 1.

PMID:
18455451
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region.

Shansab M, Eccleston JM, Selsing E.

Eur J Immunol. 2011 May;41(5):1456-64. doi: 10.1002/eji.201041077. Epub 2011 Apr 11.

PMID:
21469111
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.

Gramlich HS, Reisbig T, Schatz DG.

PLoS One. 2012;7(6):e39601. doi: 10.1371/journal.pone.0039601. Epub 2012 Jun 29.

PMID:
22768095
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.

Gazumyan A, Timachova K, Yuen G, Siden E, Di Virgilio M, Woo EM, Chait BT, Reina San-Martin B, Nussenzweig MC, McBride KM.

Mol Cell Biol. 2011 Feb;31(3):442-9. doi: 10.1128/MCB.00349-10. Epub 2010 Dec 6.

PMID:
21135131
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Activation-induced deaminase: light and dark sides.

de Yébenes VG, Ramiro AR.

Trends Mol Med. 2006 Sep;12(9):432-9. Epub 2006 Jul 24. Review.

PMID:
16861038
[PubMed - indexed for MEDLINE]
13.

Role of the translocation partner in protection against AID-dependent chromosomal translocations.

Jankovic M, Robbiani DF, Dorsett Y, Eisenreich T, Xu Y, Tarakhovsky A, Nussenzweig A, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):187-92. doi: 10.1073/pnas.0908946107. Epub 2009 Dec 4.

PMID:
19966290
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Gostissa M, Yan CT, Bianco JM, Cogné M, Pinaud E, Alt FW.

Nature. 2009 Dec 10;462(7274):803-7. doi: 10.1038/nature08633.

PMID:
20010689
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes.

Casellas R, Yamane A, Kovalchuk AL, Potter M.

Immunology. 2009 Mar;126(3):316-28. doi: 10.1111/j.1365-2567.2008.03050.x. Review.

PMID:
19302140
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T.

Nat Immunol. 2004 Jul;5(7):707-12. Epub 2004 Jun 13.

PMID:
15195091
[PubMed - indexed for MEDLINE]
18.

Regulation of AID, the B-cell genome mutator.

Keim C, Kazadi D, Rothschild G, Basu U.

Genes Dev. 2013 Jan 1;27(1):1-17. doi: 10.1101/gad.200014.112. Review.

PMID:
23307864
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo.

Sernández IV, de Yébenes VG, Dorsett Y, Ramiro AR.

PLoS One. 2008;3(12):e3927. doi: 10.1371/journal.pone.0003927. Epub 2008 Dec 12.

PMID:
19079594
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.

Zahn A, Eranki AK, Patenaude AM, Methot SP, Fifield H, Cortizas EM, Foster P, Imai K, Durandy A, Larijani M, Verdun RE, Di Noia JM.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E988-97. doi: 10.1073/pnas.1320486111. Epub 2014 Mar 3.

PMID:
24591601
[PubMed - indexed for MEDLINE]

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