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Results: 1 to 20 of 118

1.

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.

Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP.

Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5.

PMID:
22863753
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages.

Zhao W, Wang L, Zhang M, Yuan C, Gao C.

J Immunol. 2012 Mar 15;188(6):2567-74. doi: 10.4049/jimmunol.1103255. Epub 2012 Feb 8.

PMID:
22323536
[PubMed - indexed for MEDLINE]
Free Article
3.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

PMID:
19592497
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.

Mashima R, Saeki K, Aki D, Minoda Y, Takaki H, Sanada T, Kobayashi T, Aburatani H, Yamanashi Y, Yoshimura A.

J Biol Chem. 2005 Dec 16;280(50):41289-97. Epub 2005 Oct 12.

PMID:
16221674
[PubMed - indexed for MEDLINE]
Free Article
5.

Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation.

Zhang Q, Wang C, Liu Z, Liu X, Han C, Cao X, Li N.

J Biol Chem. 2012 Feb 24;287(9):6208-17. doi: 10.1074/jbc.M111.310375. Epub 2011 Dec 28.

PMID:
22205705
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK.

Xia X, Cui J, Wang HY, Zhu L, Matsueda S, Wang Q, Yang X, Hong J, Songyang Z, Chen ZJ, Wang RF.

Immunity. 2011 Jun 24;34(6):843-53. doi: 10.1016/j.immuni.2011.02.022.

PMID:
21703539
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Moesin-induced signaling in response to lipopolysaccharide in macrophages.

Zawawi KH, Kantarci A, Schulze-Späte U, Fujita T, Batista EL Jr, Amar S, Van Dyke TE.

J Periodontal Res. 2010 Oct;45(5):589-601. doi: 10.1111/j.1600-0765.2010.01271.x. Epub 2010 Jun 10.

PMID:
20546116
[PubMed - indexed for MEDLINE]
8.

Pattern recognition scavenger receptor CD204 attenuates Toll-like receptor 4-induced NF-kappaB activation by directly inhibiting ubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.

Yu X, Yi H, Guo C, Zuo D, Wang Y, Kim HL, Subjeck JR, Wang XY.

J Biol Chem. 2011 May 27;286(21):18795-806. doi: 10.1074/jbc.M111.224345. Epub 2011 Apr 1.

PMID:
21460221
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.

Jakus PB, Kalman N, Antus C, Radnai B, Tucsek Z, Gallyas F Jr, Sumegi B, Veres B.

J Nutr Biochem. 2013 May;24(5):819-23. doi: 10.1016/j.jnutbio.2012.04.017. Epub 2012 Aug 24.

PMID:
22925919
[PubMed - indexed for MEDLINE]
10.

IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways.

Zhao J, Kong HJ, Li H, Huang B, Yang M, Zhu C, Bogunovic M, Zheng F, Mayer L, Ozato K, Unkeless J, Xiong H.

J Biol Chem. 2006 Apr 14;281(15):10073-80. Epub 2006 Feb 16.

PMID:
16484229
[PubMed - indexed for MEDLINE]
Free Article
11.

Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages.

Chaurasia B, Mauer J, Koch L, Goldau J, Kock AS, Brüning JC.

Mol Cell Biol. 2010 Sep;30(17):4354-66. doi: 10.1128/MCB.00069-10. Epub 2010 Jun 28.

PMID:
20584979
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

PMID:
19479062
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages.

Minematsu H, Shin MJ, Celil Aydemir AB, Kim KO, Nizami SA, Chung GJ, Lee FY.

Cell Signal. 2011 Nov;23(11):1785-93. doi: 10.1016/j.cellsig.2011.06.013. Epub 2011 Jun 25.

PMID:
21726630
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

SHP limits TLR signaling, an inducible transcriptional corepressor.

Zhang J, Shen B.

Cell Mol Immunol. 2011 Nov;8(6):445-6. doi: 10.1038/cmi.2011.31. Epub 2011 Aug 22. No abstract available.

PMID:
21860408
[PubMed - indexed for MEDLINE]
16.
17.

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.

Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC.

Mol Cell Biol. 2007 Sep;27(17):6012-25. Epub 2007 Jun 11.

PMID:
17562858
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

PMID:
12496438
[PubMed - indexed for MEDLINE]
Free Article
19.

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.

Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G.

Nat Immunol. 2006 Feb;7(2):139-47. Epub 2005 Dec 25.

PMID:
16378096
[PubMed - indexed for MEDLINE]
20.

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.

Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD.

Mol Cell Biol. 2008 May;28(10):3538-47. doi: 10.1128/MCB.02098-07. Epub 2008 Mar 17.

PMID:
18347055
[PubMed - indexed for MEDLINE]
Free PMC Article

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