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Items: 1 to 20 of 105

1.

Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

Hable V, Drexler GA, Brüning T, Burgdorf C, Greubel C, Derer A, Seel J, Strickfaden H, Cremer T, Friedl AA, Dollinger G.

PLoS One. 2012;7(7):e41943. doi: 10.1371/journal.pone.0041943. Epub 2012 Jul 30.

2.

53BP1 and MDC1 foci formation in HT-1080 cells for low- and high-LET microbeam irradiations.

Mosconi M, Giesen U, Langner F, Mielke C, Dalla Rosa I, Dirks WG.

Radiat Environ Biophys. 2011 Aug;50(3):345-52. doi: 10.1007/s00411-011-0366-9. Epub 2011 May 11.

PMID:
21559952
3.

Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci.

Mok MT, Henderson BR.

Radiother Oncol. 2012 Jun;103(3):415-20. doi: 10.1016/j.radonc.2012.04.009. Epub 2012 May 24.

PMID:
22633816
4.

The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.

Mok MT, Henderson BR.

Int J Biochem Cell Biol. 2012 Sep;44(9):1398-409. doi: 10.1016/j.biocel.2012.05.025. Epub 2012 Jun 5.

PMID:
22677490
5.

Differences in DNA double strand breaks repair in male germ cell types: lessons learned from a differential expression of Mdc1 and 53BP1.

Ahmed EA, van der Vaart A, Barten A, Kal HB, Chen J, Lou Z, Minter-Dykhouse K, Bartkova J, Bartek J, de Boer P, de Rooij DG.

DNA Repair (Amst). 2007 Sep 1;6(9):1243-54. Epub 2007 Mar 21.

PMID:
17376750
6.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.

PMID:
21036673
7.

Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80.

Strauss C, Goldberg M.

Cell Cycle. 2011 Sep 1;10(17):2850-7. Epub 2011 Sep 1.

PMID:
21857162
8.

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.

Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM, Dantuma NP, Lukas J, Vermeulen W.

J Cell Biol. 2009 Sep 21;186(6):835-47. doi: 10.1083/jcb.200902150.

9.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
10.

Nanoscale analysis of clustered DNA damage after high-LET irradiation by quantitative electron microscopy--the heavy burden to repair.

Lorat Y, Brunner CU, Schanz S, Jakob B, Taucher-Scholz G, Rübe CE.

DNA Repair (Amst). 2015 Apr;28:93-106. doi: 10.1016/j.dnarep.2015.01.007. Epub 2015 Jan 28.

PMID:
25659339
11.
12.

Spatiotemporal dynamics of early DNA damage response proteins on complex DNA lesions.

Tobias F, Löb D, Lengert N, Durante M, Drossel B, Taucher-Scholz G, Jakob B.

PLoS One. 2013;8(2):e57953. doi: 10.1371/journal.pone.0057953. Epub 2013 Feb 26.

13.

The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.

Eliezer Y, Argaman L, Rhie A, Doherty AJ, Goldberg M.

J Biol Chem. 2009 Jan 2;284(1):426-35. doi: 10.1074/jbc.M807375200. Epub 2008 Nov 5.

14.

Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts.

Asaithamby A, Uematsu N, Chatterjee A, Story MD, Burma S, Chen DJ.

Radiat Res. 2008 Apr;169(4):437-46. doi: 10.1667/RR1165.1.

PMID:
18363429
15.

Spatial dynamics of DNA damage response protein foci along the ion trajectory of high-LET particles.

Du G, Drexler GA, Friedland W, Greubel C, Hable V, Krücken R, Kugler A, Tonelli L, Friedl AA, Dollinger G.

Radiat Res. 2011 Dec;176(6):706-15. Epub 2011 Jul 28.

PMID:
21797665
16.

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells.

Gou Q, Xie Y, Liu L, Xie K, Wu Y, Wang Q, Wang Z, Li P.

Oncol Rep. 2015 Jul;34(1):251-7. doi: 10.3892/or.2015.3980. Epub 2015 May 14.

PMID:
25976740
17.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
18.

Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation.

Shi W, Ma Z, Willers H, Akhtar K, Scott SP, Zhang J, Powell S, Zhang J.

J Biol Chem. 2008 Nov 14;283(46):31608-16. doi: 10.1074/jbc.M801082200. Epub 2008 Aug 29.

19.

Effects of radiation quality and oxygen on clustered DNA lesions and cell death.

Stewart RD, Yu VK, Georgakilas AG, Koumenis C, Park JH, Carlson DJ.

Radiat Res. 2011 Nov;176(5):587-602. Epub 2011 Aug 8.

PMID:
21823972
20.
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