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Items: 1 to 20 of 83

1.

Opening and closing of the bacterial RNA polymerase clamp.

Chakraborty A, Wang D, Ebright YW, Korlann Y, Kortkhonjia E, Kim T, Chowdhury S, Wigneshweraraj S, Irschik H, Jansen R, Nixon BT, Knight J, Weiss S, Ebright RH.

Science. 2012 Aug 3;337(6094):591-5. doi: 10.1126/science.1218716.

2.

Multiple roles of the RNA polymerase {beta}' SW2 region in transcription initiation, promoter escape, and RNA elongation.

Pupov D, Miropolskaya N, Sevostyanova A, Bass I, Artsimovitch I, Kulbachinskiy A.

Nucleic Acids Res. 2010 Sep;38(17):5784-96. doi: 10.1093/nar/gkq355. Epub 2010 May 10.

3.

The initiation factor TFE and the elongation factor Spt4/5 compete for the RNAP clamp during transcription initiation and elongation.

Grohmann D, Nagy J, Chakraborty A, Klose D, Fielden D, Ebright RH, Michaelis J, Werner F.

Mol Cell. 2011 Jul 22;43(2):263-74. doi: 10.1016/j.molcel.2011.05.030.

4.

Mechanism of bacterial transcription initiation: RNA polymerase - promoter binding, isomerization to initiation-competent open complexes, and initiation of RNA synthesis.

Saecker RM, Record MT Jr, Dehaseth PL.

J Mol Biol. 2011 Oct 7;412(5):754-71. doi: 10.1016/j.jmb.2011.01.018. Epub 2011 Mar 1.

5.

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.

Kapanidis AN, Margeat E, Ho SO, Kortkhonjia E, Weiss S, Ebright RH.

Science. 2006 Nov 17;314(5802):1144-7.

6.

TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle.

Schulz S, Gietl A, Smollett K, Tinnefeld P, Werner F, Grohmann D.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1816-25. doi: 10.1073/pnas.1515817113. Epub 2016 Mar 15. Erratum in: Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2871.

7.

Transcription initiation in a single-subunit RNA polymerase proceeds through DNA scrunching and rotation of the N-terminal subdomains.

Tang GQ, Roy R, Ha T, Patel SS.

Mol Cell. 2008 Jun 6;30(5):567-77. doi: 10.1016/j.molcel.2008.04.003.

8.

DNA structure requirements for the Escherichia coli gamma complex clamp loader and DNA polymerase III holoenzyme.

Yao N, Leu FP, Anjelkovic J, Turner J, O'Donnell M.

J Biol Chem. 2000 Apr 14;275(15):11440-50.

9.

T7 RNA polymerase-induced bending of promoter DNA is coupled to DNA opening.

Tang GQ, Patel SS.

Biochemistry. 2006 Apr 18;45(15):4936-46.

PMID:
16605261
10.

RNA-binding to archaeal RNA polymerase subunits F/E: a DEER and FRET study.

Grohmann D, Klose D, Klare JP, Kay CW, Steinhoff HJ, Werner F.

J Am Chem Soc. 2010 May 5;132(17):5954-5. doi: 10.1021/ja101663d.

PMID:
20384325
11.

One-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex.

Gries TJ, Kontur WS, Capp MW, Saecker RM, Record MT Jr.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10418-23. doi: 10.1073/pnas.1000967107. Epub 2010 May 18.

13.

Collective motions of RNA polymerases. Analysis of core enzyme, elongation complex and holoenzyme.

Yildirim Y, Doruker P.

J Biomol Struct Dyn. 2004 Dec;22(3):267-80.

PMID:
15473702
14.
15.

Structural transitions in the transcription elongation complexes of bacterial RNA polymerase during σ-dependent pausing.

Zhilina E, Esyunina D, Brodolin K, Kulbachinskiy A.

Nucleic Acids Res. 2012 Apr;40(7):3078-91. doi: 10.1093/nar/gkr1158. Epub 2011 Dec 2.

16.

Sensing DNA opening in transcription using quenchable Förster resonance energy transfer.

Cordes T, Santoso Y, Tomescu AI, Gryte K, Hwang LC, Camará B, Wigneshweraraj S, Kapanidis AN.

Biochemistry. 2010 Nov 2;49(43):9171-80. doi: 10.1021/bi101184g.

PMID:
20818825
17.

Structural basis of transcription initiation.

Zhang Y, Feng Y, Chatterjee S, Tuske S, Ho MX, Arnold E, Ebright RH.

Science. 2012 Nov 23;338(6110):1076-80. doi: 10.1126/science.1227786. Epub 2012 Oct 18.

18.

The RNA polymerase "switch region" is a target for inhibitors.

Mukhopadhyay J, Das K, Ismail S, Koppstein D, Jang M, Hudson B, Sarafianos S, Tuske S, Patel J, Jansen R, Irschik H, Arnold E, Ebright RH.

Cell. 2008 Oct 17;135(2):295-307. doi: 10.1016/j.cell.2008.09.033.

19.

Promoter binding, initiation, and elongation by bacteriophage T7 RNA polymerase. A single-molecule view of the transcription cycle.

Skinner GM, Baumann CG, Quinn DM, Molloy JE, Hoggett JG.

J Biol Chem. 2004 Jan 30;279(5):3239-44. Epub 2003 Nov 3.

20.

Functional architecture of T7 RNA polymerase transcription complexes.

Nayak D, Guo Q, Sousa R.

J Mol Biol. 2007 Aug 10;371(2):490-500. Epub 2007 May 31.

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