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Items: 1 to 20 of 174

1.

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.

Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Huebner AK, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T.

J Neuroendocrinol. 2013 Jan;25(1):14-22. doi: 10.1111/j.1365-2826.2012.02366.x.

PMID:
22849972
2.

Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice.

Mody N, Graham TE, Tsuji Y, Yang Q, Kahn BB.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E785-93. doi: 10.1152/ajpendo.00521.2007. Epub 2008 Feb 19.

3.

Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.

Makimura H, Mizuno TM, Roberts J, Silverstein J, Beasley J, Mobbs CV.

Diabetes. 2000 Nov;49(11):1917-23.

PMID:
11078460
4.

Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice.

Begriche K, Lettéron P, Abbey-Toby A, Vadrot N, Robin MA, Bado A, Pessayre D, Fromenty B.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E939-51. doi: 10.1152/ajpendo.00379.2007. Epub 2008 Mar 18.

5.

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.

6.

Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.

Xu J, Kulkarni SR, Donepudi AC, More VR, Slitt AL.

Diabetes. 2012 Dec;61(12):3208-18. doi: 10.2337/db11-1716. Epub 2012 Aug 30.

7.

High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice.

Townsend KL, Lorenzi MM, Widmaier EP.

Endocrine. 2008 Apr;33(2):176-88. doi: 10.1007/s12020-008-9070-1. Epub 2008 May 16.

PMID:
18483882
8.

Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions.

Ohnishi M, Kato S, Akiyoshi J, Atfi A, Razzaque MS.

FASEB J. 2011 Jun;25(6):2031-9. doi: 10.1096/fj.10-167056. Epub 2011 Mar 7.

9.
10.

Loss of resistin ameliorates hyperlipidemia and hepatic steatosis in leptin-deficient mice.

Singhal NS, Patel RT, Qi Y, Lee YS, Ahima RS.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E331-8. doi: 10.1152/ajpendo.00577.2007. Epub 2008 May 27.

11.

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.

Sun Y, Asnicar M, Saha PK, Chan L, Smith RG.

Cell Metab. 2006 May;3(5):379-86.

12.

Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice.

Wendel AA, Purushotham A, Liu LF, Belury MA.

J Lipid Res. 2008 Jan;49(1):98-106. Epub 2007 Sep 28.

13.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

14.

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.

Zemany L, Bhanot S, Peroni OD, Murray SF, Moraes-Vieira PM, Castoldi A, Manchem P, Guo S, Monia BP, Kahn BB.

Diabetes. 2015 May;64(5):1603-14. doi: 10.2337/db14-0970. Epub 2014 Dec 18.

15.

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.

Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr, Woods SC, Seeley RJ, Weigle DS.

Diabetes. 1996 Apr;45(4):531-5.

PMID:
8603777
16.
17.

Brown Adipose Tissue Transplantation Reverses Obesity in Ob/Ob Mice.

Liu X, Wang S, You Y, Meng M, Zheng Z, Dong M, Lin J, Zhao Q, Zhang C, Yuan X, Hu T, Liu L, Huang Y, Zhang L, Wang D, Zhan J, Jong Lee H, Speakman JR, Jin W.

Endocrinology. 2015 Jul;156(7):2461-9. doi: 10.1210/en.2014-1598. Epub 2015 Apr 1.

PMID:
25830704
18.

Beta-aminoisobutyric acid prevents diet-induced obesity in mice with partial leptin deficiency.

Begriche K, Massart J, Abbey-Toby A, Igoudjil A, Lettéron P, Fromenty B.

Obesity (Silver Spring). 2008 Sep;16(9):2053-67. doi: 10.1038/oby.2008.337.

19.

Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice.

Iwaniec UT, Boghossian S, Lapke PD, Turner RT, Kalra SP.

Peptides. 2007 May;28(5):1012-9. Epub 2007 Feb 12.

20.

Fenretinide ameliorates insulin resistance and fatty liver in obese mice.

Koh IU, Jun HS, Choi JS, Lim JH, Kim WH, Yoon JB, Song J.

Biol Pharm Bull. 2012;35(3):369-75.

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