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The aging epigenome: DNA methylation from the cradle to the grave.

Winnefeld M, Lyko F.

Genome Biol. 2012 Jul 30;13(7):165. doi: 10.1186/gb4033.


Analysis of Guthrie cards could provide insight into the epigenome at birth.

Wilkinson J.

Epigenomics. 2012 Oct;4(5):480-1. No abstract available.


Using epigenome-wide association scans of DNA methylation in age-related complex human traits.

Tsai PC, Spector TD, Bell JT.

Epigenomics. 2012 Oct;4(5):511-26. doi: 10.2217/epi.12.45. Review.


Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.

Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT.

PLoS Genet. 2009 Aug;5(8):e1000602. doi: 10.1371/journal.pgen.1000602. Epub 2009 Aug 14.


Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.

Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.

Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi: 10.1093/hmg/ddt531. Epub 2013 Oct 26.


Aging effects on DNA methylation modules in human brain and blood tissue.

Horvath S, Zhang Y, Langfelder P, Kahn RS, Boks MP, van Eijk K, van den Berg LH, Ophoff RA.

Genome Biol. 2012 Oct 3;13(10):R97. doi: 10.1186/gb-2012-13-10-r97.


Mapping human epigenomes.

Rivera CM, Ren B.

Cell. 2013 Sep 26;155(1):39-55. doi: 10.1016/j.cell.2013.09.011. Review.


Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians' offspring.

Gentilini D, Mari D, Castaldi D, Remondini D, Ogliari G, Ostan R, Bucci L, Sirchia SM, Tabano S, Cavagnini F, Monti D, Franceschi C, Di Blasio AM, Vitale G.

Age (Dordr). 2013 Oct;35(5):1961-73. doi: 10.1007/s11357-012-9463-1. Epub 2012 Aug 25.


Epigenomics and the regulation of aging.

Boyd-Kirkup JD, Green CD, Wu G, Wang D, Han JD.

Epigenomics. 2013 Apr;5(2):205-27. doi: 10.2217/epi.13.5. Review.


Genome-wide methylation profiles reveal quantitative views of human aging rates.

Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, Zhang K.

Mol Cell. 2013 Jan 24;49(2):359-67. doi: 10.1016/j.molcel.2012.10.016. Epub 2012 Nov 21.


Epigenetic genome-wide association methylation in aging and longevity.

Ben-Avraham D, Muzumdar RH, Atzmon G.

Epigenomics. 2012 Oct;4(5):503-9. doi: 10.2217/epi.12.41. Review.


Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance.

Martino D, Loke YJ, Gordon L, Ollikainen M, Cruickshank MN, Saffery R, Craig JM.

Genome Biol. 2013 May 22;14(5):R42. doi: 10.1186/gb-2013-14-5-r42.


Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence.

Gordon L, Joo JE, Powell JE, Ollikainen M, Novakovic B, Li X, Andronikos R, Cruickshank MN, Conneely KN, Smith AK, Alisch RS, Morley R, Visscher PM, Craig JM, Saffery R.

Genome Res. 2012 Aug;22(8):1395-406. doi: 10.1101/gr.136598.111. Epub 2012 Jul 16.


DNA methylation and epigenotypes.

Holliday R.

Biochemistry (Mosc). 2005 May;70(5):500-4. Review.


Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.

Wolber LE, Steves CJ, Tsai PC, Deloukas P, Spector TD, Bell JT, Williams FM.

PLoS One. 2014 Sep 3;9(9):e105729. doi: 10.1371/journal.pone.0105729. eCollection 2014.


EpiExplorer: live exploration and global analysis of large epigenomic datasets.

Halachev K, Bast H, Albrecht F, Lengauer T, Bock C.

Genome Biol. 2012 Oct 3;13(10):R96. doi: 10.1186/gb-2012-13-10-r96.


DNA methylation analysis in human cancer.

O'Sullivan E, Goggins M.

Methods Mol Biol. 2013;980:131-56. doi: 10.1007/978-1-62703-287-2_7.


Epigenetic dysregulation in Alzheimer's disease: cause or consequence?

van den Hove DL, Kenis G, Rutten BP.

Epigenomics. 2014 Feb;6(1):9-11. doi: 10.2217/epi.13.84. No abstract available.


Aging of blood can be tracked by DNA methylation changes at just three CpG sites.

Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, Bauerschlag DO, Jöckel KH, Erbel R, Mühleisen TW, Zenke M, Brümmendorf TH, Wagner W.

Genome Biol. 2014 Feb 3;15(2):R24. doi: 10.1186/gb-2014-15-2-r24.


An integrated workflow for DNA methylation analysis.

Li P, Demirci F, Mahalingam G, Demirci C, Nakano M, Meyers BC.

J Genet Genomics. 2013 May 20;40(5):249-60. doi: 10.1016/j.jgg.2013.03.010. Epub 2013 Mar 30. Review.

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