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Items: 1 to 20 of 127

1.

Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes.

Sinnesael M, Claessens F, Laurent M, Dubois V, Boonen S, Deboel L, Vanderschueren D.

J Bone Miner Res. 2012 Dec;27(12):2535-43. doi: 10.1002/jbmr.1713.

2.

Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model.

Venken K, De Gendt K, Boonen S, Ophoff J, Bouillon R, Swinnen JV, Verhoeven G, Vanderschueren D.

J Bone Miner Res. 2006 Apr;21(4):576-85. Epub 2006 Apr 5.

3.

Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice.

Notini AJ, McManus JF, Moore A, Bouxsein M, Jimenez M, Chiu WS, Glatt V, Kream BE, Handelsman DJ, Morris HA, Zajac JD, Davey RA.

J Bone Miner Res. 2007 Mar;22(3):347-56.

4.

Identification of gene pathways altered by deletion of the androgen receptor specifically in mineralizing osteoblasts and osteocytes in mice.

Russell PK, Clarke MV, Skinner JP, Pang TP, Zajac JD, Davey RA.

J Mol Endocrinol. 2012 May 29;49(1):1-10. doi: 10.1530/JME-12-0014. Print 2012 Aug.

5.

Mineralization and bone resorption are regulated by the androgen receptor in male mice.

Chiang C, Chiu M, Moore AJ, Anderson PH, Ghasem-Zadeh A, McManus JF, Ma C, Seeman E, Clemens TL, Morris HA, Zajac JD, Davey RA.

J Bone Miner Res. 2009 Apr;24(4):621-31. doi: 10.1359/jbmr.081217.

6.

DNA-binding-dependent androgen receptor signaling contributes to gender differences and has physiological actions in males and females.

MacLean HE, Moore AJ, Sastra SA, Morris HA, Ghasem-Zadeh A, Rana K, Axell AM, Notini AJ, Handelsman DJ, Seeman E, Zajac JD, Davey RA.

J Endocrinol. 2010 Jul;206(1):93-103. doi: 10.1677/JOE-10-0026. Epub 2010 Apr 15.

7.

Mef2c deletion in osteocytes results in increased bone mass.

Kramer I, Baertschi S, Halleux C, Keller H, Kneissel M.

J Bone Miner Res. 2012 Feb;27(2):360-73. doi: 10.1002/jbmr.1492.

8.

Osteoblast and osteocyte apoptosis associated with androgen action in bone: requirement of increased Bax/Bcl-2 ratio.

Wiren KM, Toombs AR, Semirale AA, Zhang X.

Bone. 2006 May;38(5):637-51. Epub 2006 Jan 18.

PMID:
16413235
9.

Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses.

Powell WF Jr, Barry KJ, Tulum I, Kobayashi T, Harris SE, Bringhurst FR, Pajevic PD.

J Endocrinol. 2011 Apr;209(1):21-32. doi: 10.1530/JOE-10-0308. Epub 2011 Jan 10.

10.

The reduced trabecular bone mass of adult ARKO male mice results from the decreased osteogenic differentiation of bone marrow stroma cells.

Tsai MY, Shyr CR, Kang HY, Chang YC, Weng PL, Wang SY, Huang KE, Chang C.

Biochem Biophys Res Commun. 2011 Aug 5;411(3):477-82. doi: 10.1016/j.bbrc.2011.06.113. Epub 2011 Jun 23.

PMID:
21723262
11.

Constitutive protein kinase A activity in osteocytes and late osteoblasts produces an anabolic effect on bone.

Kao RS, Abbott MJ, Louie A, O'Carroll D, Lu W, Nissenson R.

Bone. 2013 Aug;55(2):277-87. doi: 10.1016/j.bone.2013.04.001. Epub 2013 Apr 10.

12.

Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo.

Yang W, Lu Y, Kalajzic I, Guo D, Harris MA, Gluhak-Heinrich J, Kotha S, Bonewald LF, Feng JQ, Rowe DW, Turner CH, Robling AG, Harris SE.

J Biol Chem. 2005 May 27;280(21):20680-90. Epub 2005 Feb 22.

13.

Androgen prevents hypogonadal bone loss via inhibition of resorption mediated by mature osteoblasts/osteocytes.

Wiren KM, Zhang XW, Olson DA, Turner RT, Iwaniec UT.

Bone. 2012 Nov;51(5):835-46. doi: 10.1016/j.bone.2012.08.111. Epub 2012 Aug 14.

14.

Notch signaling in osteocytes differentially regulates cancellous and cortical bone remodeling.

Canalis E, Adams DJ, Boskey A, Parker K, Kranz L, Zanotti S.

J Biol Chem. 2013 Aug 30;288(35):25614-25. doi: 10.1074/jbc.M113.470492. Epub 2013 Jul 24.

15.

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model.

Vandenput L, Swinnen JV, Boonen S, Van Herck E, Erben RG, Bouillon R, Vanderschueren D.

J Bone Miner Res. 2004 Sep;19(9):1462-70. Epub 2004 May 10.

16.

Suppressive function of androgen receptor in bone resorption.

Kawano H, Sato T, Yamada T, Matsumoto T, Sekine K, Watanabe T, Nakamura T, Fukuda T, Yoshimura K, Yoshizawa T, Aihara K, Yamamoto Y, Nakamichi Y, Metzger D, Chambon P, Nakamura K, Kawaguchi H, Kato S.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9416-21. Epub 2003 Jul 18.

17.

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice.

Windahl SH, Börjesson AE, Farman HH, Engdahl C, Movérare-Skrtic S, Sjögren K, Lagerquist MK, Kindblom JM, Koskela A, Tuukkanen J, Divieti Pajevic P, Feng JQ, Dahlman-Wright K, Antonson P, Gustafsson JÅ, Ohlsson C.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2294-9. doi: 10.1073/pnas.1220811110. Epub 2013 Jan 23.

18.

Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice.

Xiao Z, Dallas M, Qiu N, Nicolella D, Cao L, Johnson M, Bonewald L, Quarles LD.

FASEB J. 2011 Jul;25(7):2418-32. doi: 10.1096/fj.10-180299. Epub 2011 Mar 31.

19.

Effects of sex steroid receptor specificity in the regulation of skeletal metabolism.

Tözüm TF, Oppenlander ME, Koh-Paige AJ, Robins DM, McCauley LK.

Calcif Tissue Int. 2004 Jul;75(1):60-70.

PMID:
15037970
20.

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis.

Kramer I, Halleux C, Keller H, Pegurri M, Gooi JH, Weber PB, Feng JQ, Bonewald LF, Kneissel M.

Mol Cell Biol. 2010 Jun;30(12):3071-85. doi: 10.1128/MCB.01428-09. Epub 2010 Apr 19.

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