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Items: 1 to 20 of 125


A transposon-based analysis of gene mutations related to skin cancer development.

Quintana RM, Dupuy AJ, Bravo A, Casanova ML, Alameda JP, Page A, Sánchez-Viera M, Ramírez A, Navarro M.

J Invest Dermatol. 2013 Jan;133(1):239-48. doi: 10.1038/jid.2012.245. Epub 2012 Jul 26.


Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.

Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM.

Oncogene. 2006 Jul 6;25(29):4027-32. Epub 2006 Mar 6.


Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.

Kiguchi K, Bol D, Carbajal S, Beltrán L, Moats S, Chan K, Jorcano J, DiGiovanni J.

Oncogene. 2000 Aug 31;19(37):4243-54.


Identification of Sleeping Beauty transposon insertions in solid tumors using linker-mediated PCR.

Janik CL, Starr TK.

J Vis Exp. 2013 Feb 1;(72):e50156. doi: 10.3791/50156.


Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.

Owens DM, Spalding JW, Tennant RW, Smart RC.

Cancer Res. 1995 Jul 15;55(14):3171-8.


A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice.

Dupuy AJ, Rogers LM, Kim J, Nannapaneni K, Starr TK, Liu P, Largaespada DA, Scheetz TE, Jenkins NA, Copeland NG.

Cancer Res. 2009 Oct 15;69(20):8150-6. doi: 10.1158/0008-5472.CAN-09-1135. Epub 2009 Oct 6.


Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.

Muto S, Katsuki M, Horie S.

Cancer Sci. 2007 Oct;98(10):1549-56. Epub 2007 Aug 7.


Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.

Wei SJ, Chang RL, Merkler KA, Gwynne M, Cui XX, Murthy B, Huang MT, Xie JG, Lu YP, Lou YR, Jerina DM, Conney AH.

Carcinogenesis. 1999 Sep;20(9):1689-96.


Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients.

Couvé-Privat S, Le Bret M, Traiffort E, Queille S, Coulombe J, Bouadjar B, Avril MF, Ruat M, Sarasin A, Daya-Grosjean L.

Cancer Res. 2004 May 15;64(10):3559-65.


A DNA transposon-based approach to validate oncogenic mutations in the mouse.

Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19904-9. doi: 10.1073/pnas.0807785105. Epub 2008 Dec 8.


Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8.

Schaper ID, Marcuzzi GP, Weissenborn SJ, Kasper HU, Dries V, Smyth N, Fuchs P, Pfister H.

Cancer Res. 2005 Feb 15;65(4):1394-400.


A multihit, multistage model of chemical carcinogenesis.

Owens DM, Wei S, Smart RC.

Carcinogenesis. 1999 Sep;20(9):1837-44.


Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis.

Vitale-Cross L, Amornphimoltham P, Fisher G, Molinolo AA, Gutkind JS.

Cancer Res. 2004 Dec 15;64(24):8804-7.

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