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Items: 1 to 20 of 93


A fine scale phenotype-genotype virulence map of a bacterial pathogen.

van Opijnen T, Camilli A.

Genome Res. 2012 Dec;22(12):2541-51. doi: 10.1101/gr.137430.112. Epub 2012 Jul 23.


A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae.

Mahdi LK, Ebrahimie E, Adelson DL, Paton JC, Ogunniyi AD.

PLoS One. 2013 Aug 13;8(8):e70862. doi: 10.1371/journal.pone.0070862. eCollection 2013.


Genome-wide fitness and genetic interactions determined by Tn-seq, a high-throughput massively parallel sequencing method for microorganisms.

van Opijnen T, Camilli A.

Curr Protoc Microbiol. 2010 Nov;Chapter 1:Unit1E.3. doi: 10.1002/9780471729259.mc01e03s19.


Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.

Tettelin H, Nelson KE, Paulsen IT, Eisen JA, Read TD, Peterson S, Heidelberg J, DeBoy RT, Haft DH, Dodson RJ, Durkin AS, Gwinn M, Kolonay JF, Nelson WC, Peterson JD, Umayam LA, White O, Salzberg SL, Lewis MR, Radune D, Holtzapple E, Khouri H, Wolf AM, Utterback TR, Hansen CL, McDonald LA, Feldblyum TV, Angiuoli S, Dickinson T, Hickey EK, Holt IE, Loftus BJ, Yang F, Smith HO, Venter JC, Dougherty BA, Morrison DA, Hollingshead SK, Fraser CM.

Science. 2001 Jul 20;293(5529):498-506.


A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence.

Harvey RM, Stroeher UH, Ogunniyi AD, Smith-Vaughan HC, Leach AJ, Paton JC.

PLoS One. 2011 May 5;6(5):e19650. doi: 10.1371/journal.pone.0019650.


Role of two-component systems in the virulence of Streptococcus pneumoniae.

Paterson GK, Blue CE, Mitchell TJ.

J Med Microbiol. 2006 Apr;55(Pt 4):355-63. Review.


LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes.

Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S.

Infect Immun. 2004 May;72(5):2964-75.


Large-scale identification of virulence genes from Streptococcus pneumoniae.

Polissi A, Pontiggia A, Feger G, Altieri M, Mottl H, Ferrari L, Simon D.

Infect Immun. 1998 Dec;66(12):5620-9.


Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone.

Hiller NL, Eutsey RA, Powell E, Earl JP, Janto B, Martin DP, Dawid S, Ahmed A, Longwell MJ, Dahlgren ME, Ezzo S, Tettelin H, Daugherty SC, Mitchell TJ, Hillman TA, Buchinsky FJ, Tomasz A, de Lencastre H, Sá-Leão R, Post JC, Hu FZ, Ehrlich GD.

PLoS One. 2011;6(12):e28850. doi: 10.1371/journal.pone.0028850. Epub 2011 Dec 19.


Identification of Streptococcus pneumoniae genes specifically induced in mouse lung tissues.

Meng JP, Yin YB, Zhang XM, Huang YS, Lan K, Cui F, Xu SX.

Can J Microbiol. 2008 Jan;54(1):58-65. doi: 10.1139/w07-117.


CRISPR interference can prevent natural transformation and virulence acquisition during in vivo bacterial infection.

Bikard D, Hatoum-Aslan A, Mucida D, Marraffini LA.

Cell Host Microbe. 2012 Aug 16;12(2):177-86. doi: 10.1016/j.chom.2012.06.003.


A locus contained within a variable region of pneumococcal pathogenicity island 1 contributes to virulence in mice.

Brown JS, Gilliland SM, Spratt BG, Holden DW.

Infect Immun. 2004 Mar;72(3):1587-93.


The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease.

Kadioglu A, Weiser JN, Paton JC, Andrew PW.

Nat Rev Microbiol. 2008 Apr;6(4):288-301. doi: 10.1038/nrmicro1871. Review.


Differential fluorescence induction reveals Streptococcus pneumoniae loci regulated by competence stimulatory peptide.

Bartilson M, Marra A, Christine J, Asundi JS, Schneider WP, Hromockyj AE.

Mol Microbiol. 2001 Jan;39(1):126-35.

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