Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 113

1.

Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13.

Bergeret F, Gavalda S, Chalut C, Malaga W, Quémard A, Pedelacq JD, Daffé M, Guilhot C, Mourey L, Bon C.

J Biol Chem. 2012 Sep 28;287(40):33675-90. Epub 2012 Jul 23.

PMID:
22825853
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis.

Gavalda S, Léger M, van der Rest B, Stella A, Bardou F, Montrozier H, Chalut C, Burlet-Schiltz O, Marrakchi H, Daffé M, Quémard A.

J Biol Chem. 2009 Jul 17;284(29):19255-64. doi: 10.1074/jbc.M109.006940. Epub 2009 May 12.

PMID:
19436070
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis.

Liew CW, Nilsson M, Chen MW, Sun H, Cornvik T, Liang ZX, Lescar J.

J Biol Chem. 2012 Jun 29;287(27):23203-15. doi: 10.1074/jbc.M112.362210. Epub 2012 May 15.

PMID:
22589546
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis.

Wilson R, Kumar P, Parashar V, Vilchèze C, Veyron-Churlet R, Freundlich JS, Barnes SW, Walker JR, Szymonifka MJ, Marchiano E, Shenai S, Colangeli R, Jacobs WR Jr, Neiditch MB, Kremer L, Alland D.

Nat Chem Biol. 2013 Aug;9(8):499-506. doi: 10.1038/nchembio.1277. Epub 2013 Jun 16.

PMID:
23770708
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth: identification of the carboxylation product and determination of the acyl-CoA carboxylase components.

Portevin D, de Sousa-D'Auria C, Montrozier H, Houssin C, Stella A, Lanéelle MA, Bardou F, Guilhot C, Daffé M.

J Biol Chem. 2005 Mar 11;280(10):8862-74. Epub 2005 Jan 4.

PMID:
15632194
[PubMed - indexed for MEDLINE]
Free Article
6.

Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis.

Gande R, Gibson KJ, Brown AK, Krumbach K, Dover LG, Sahm H, Shioyama S, Oikawa T, Besra GS, Eggeling L.

J Biol Chem. 2004 Oct 22;279(43):44847-57. Epub 2004 Aug 11.

PMID:
15308633
[PubMed - indexed for MEDLINE]
Free Article
7.

Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.

Chopra T, Banerjee S, Gupta S, Yadav G, Anand S, Surolia A, Roy RP, Mohanty D, Gokhale RS.

PLoS Biol. 2008 Jul 8;6(7):e163. doi: 10.1371/journal.pbio.0060163.

PMID:
18613748
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The biosynthesis of mycolic acids in Mycobacterium tuberculosis relies on multiple specialized elongation complexes interconnected by specific protein-protein interactions.

Veyron-Churlet R, Bigot S, Guerrini O, Verdoux S, Malaga W, Daffé M, Zerbib D.

J Mol Biol. 2005 Nov 4;353(4):847-58. Epub 2005 Sep 23.

PMID:
16213523
[PubMed - indexed for MEDLINE]
9.

Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.

Dym O, Albeck S, Peleg Y, Schwarz A, Shakked Z, Burstein Y, Zimhony O.

J Mol Biol. 2009 Nov 6;393(4):937-50. doi: 10.1016/j.jmb.2009.08.065. Epub 2009 Sep 3.

PMID:
19733180
[PubMed - indexed for MEDLINE]
10.

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

Tang Y, Kim CY, Mathews II, Cane DE, Khosla C.

Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. Epub 2006 Jul 14.

PMID:
16844787
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The crystal structure of a mammalian fatty acid synthase.

Maier T, Leibundgut M, Ban N.

Science. 2008 Sep 5;321(5894):1315-22. doi: 10.1126/science.1161269.

PMID:
18772430
[PubMed - indexed for MEDLINE]
Free Article
12.

Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases.

Yadav G, Gokhale RS, Mohanty D.

J Mol Biol. 2003 Apr 25;328(2):335-63.

PMID:
12691745
[PubMed - indexed for MEDLINE]
13.

Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.

Hughes AJ, Keatinge-Clay A.

Chem Biol. 2011 Feb 25;18(2):165-76. doi: 10.1016/j.chembiol.2010.12.014.

PMID:
21338915
[PubMed - indexed for MEDLINE]
Free Article
14.

Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III.

Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT.

J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8.

PMID:
11278743
[PubMed - indexed for MEDLINE]
Free Article
15.

The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis.

Léger M, Gavalda S, Guillet V, van der Rest B, Slama N, Montrozier H, Mourey L, Quémard A, Daffé M, Marrakchi H.

Chem Biol. 2009 May 29;16(5):510-9. doi: 10.1016/j.chembiol.2009.03.012.

PMID:
19477415
[PubMed - indexed for MEDLINE]
Free Article
16.

Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase.

Crawford JM, Dancy BC, Hill EA, Udwary DW, Townsend CA.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16728-33. Epub 2006 Oct 27.

PMID:
17071746
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Autonomous folding of interdomain regions of a modular polyketide synthase.

Richter CD, Stanmore DA, Miguel RN, Moncrieffe MC, Tran L, Brewerton S, Meersman F, Broadhurst RW, Weissman KJ.

FEBS J. 2007 May;274(9):2196-209. Epub 2007 Apr 5.

PMID:
17419733
[PubMed - indexed for MEDLINE]
18.

Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.

Tang Y, Chen AY, Kim CY, Cane DE, Khosla C.

Chem Biol. 2007 Aug;14(8):931-43.

PMID:
17719492
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.

McCoy JG, Johnson HD, Singh S, Bingman CA, Lei IK, Thorson JS, Phillips GN Jr.

Proteins. 2009 Jan;74(1):50-60. doi: 10.1002/prot.22131.

PMID:
18561189
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa.

Rubin-Pitel SB, Zhang H, Vu T, Brunzelle JS, Zhao H, Nair SK.

Chem Biol. 2008 Oct 20;15(10):1079-90. doi: 10.1016/j.chembiol.2008.08.011.

PMID:
18940668
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk