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Items: 1 to 20 of 124

1.

Protein interactions: mapping interactome networks to support drug target discovery and selection.

De Las Rivas J, Prieto C.

Methods Mol Biol. 2012;910:279-96. doi: 10.1007/978-1-61779-965-5_12. Review.

PMID:
22821600
2.

Protein-protein interactions: network analysis and applications in drug discovery.

Bultinck J, Lievens S, Tavernier J.

Curr Pharm Des. 2012;18(30):4619-29. Review.

PMID:
22650261
3.

Interaction networks: from protein functions to drug discovery. A review.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Pathol Biol (Paris). 2009 Jun;57(4):324-33. doi: 10.1016/j.patbio.2008.10.004. Epub 2008 Dec 13. Review.

PMID:
19070972
4.

Databases of protein-protein interactions and their use in drug discovery.

Fuentes G, Oyarzabal J, Rojas AM.

Curr Opin Drug Discov Devel. 2009 May;12(3):358-66. Review.

PMID:
19396737
5.

Evaluating protein-protein interaction (PPI) networks for diseases pathway, target discovery, and drug-design using 'in silico pharmacology'.

Chakraborty C, Doss C GP, Chen L, Zhu H.

Curr Protein Pept Sci. 2014;15(6):561-71. Review.

PMID:
25059326
6.

Predicting the interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service.

Kim JG, Park D, Kim BC, Cho SW, Kim YT, Park YJ, Cho HJ, Park H, Kim KB, Yoon KO, Park SJ, Lee BM, Bhak J.

BMC Bioinformatics. 2008 Jan 24;9:41. doi: 10.1186/1471-2105-9-41.

7.

Charting plant interactomes: possibilities and challenges.

Morsy M, Gouthu S, Orchard S, Thorneycroft D, Harper JF, Mittler R, Cushman JC.

Trends Plant Sci. 2008 Apr;13(4):183-91. doi: 10.1016/j.tplants.2008.01.006. Epub 2008 Mar 7. Review.

PMID:
18329319
8.

The protein-protein interaction network of the human Sirtuin family.

Sharma A, Costantini S, Colonna G.

Biochim Biophys Acta. 2013 Oct;1834(10):1998-2009. doi: 10.1016/j.bbapap.2013.06.012. Epub 2013 Jun 28.

PMID:
23811471
9.

From protein interaction networks to novel therapeutic strategies.

Jaeger S, Aloy P.

IUBMB Life. 2012 Jun;64(6):529-37. doi: 10.1002/iub.1040. Epub 2012 May 9. Review.

10.

Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays.

Braun P.

Proteomics. 2012 May;12(10):1499-518. doi: 10.1002/pmic.201100598. Review.

PMID:
22589225
11.

An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data.

Sugaya N, Ikeda K, Tashiro T, Takeda S, Otomo J, Ishida Y, Shiratori A, Toyoda A, Noguchi H, Takeda T, Kuhara S, Sakaki Y, Iwayanagi T.

BMC Pharmacol. 2007 Aug 20;7:10.

12.

Protein-protein docking and hot-spot prediction for drug discovery.

Grosdidier S, Fernández-Recio J.

Curr Pharm Des. 2012;18(30):4607-18. Review.

PMID:
22650255
13.

Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance.

Raman K, Chandra N.

BMC Microbiol. 2008 Dec 23;8:234. doi: 10.1186/1471-2180-8-234.

14.

Network-based strategies can help mono- and poly-pharmacology drug discovery: a systems biology view.

Engin HB, Gursoy A, Nussinov R, Keskin O.

Curr Pharm Des. 2014;20(8):1201-7. Review.

PMID:
23713773
15.

Structural systems pharmacology: the role of 3D structures in next-generation drug development.

Duran-Frigola M, Mosca R, Aloy P.

Chem Biol. 2013 May 23;20(5):674-84. doi: 10.1016/j.chembiol.2013.03.004. Review.

16.

DTome: a web-based tool for drug-target interactome construction.

Sun J, Wu Y, Xu H, Zhao Z.

BMC Bioinformatics. 2012 Jun 11;13 Suppl 9:S7. doi: 10.1186/1471-2105-13-S9-S7.

17.

Information flow analysis of interactome networks.

Missiuro PV, Liu K, Zou L, Ross BC, Zhao G, Liu JS, Ge H.

PLoS Comput Biol. 2009 Apr;5(4):e1000350. doi: 10.1371/journal.pcbi.1000350. Epub 2009 Apr 10.

18.

Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome.

Ramadan E, Ward M, Guo X, Durkin SS, Sawyer A, Vilela M, Osgood C, Pothen A, Semmes OJ.

Retrovirology. 2008 Oct 15;5:92. doi: 10.1186/1742-4690-5-92.

19.

Network-based characterization of drug-regulated genes, drug targets, and toxicity.

Kotlyar M, Fortney K, Jurisica I.

Methods. 2012 Aug;57(4):499-507. doi: 10.1016/j.ymeth.2012.06.003. Epub 2012 Jun 27. Review.

20.

Predicting new molecular targets for rhein using network pharmacology.

Zhang A, Sun H, Yang B, Wang X.

BMC Syst Biol. 2012 Mar 21;6:20. doi: 10.1186/1752-0509-6-20. Retraction in: Zhang A, Sun H, Yang B, Wang X. BMC Syst Biol. 2014;8:105.

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