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Results: 1 to 20 of 128

1.

Low frequency of HIF-1α overexpression in germ cell tumors of the testis.

Vranic S, Hes O, Grossmann P, Gatalica Z.

Appl Immunohistochem Mol Morphol. 2013 Mar;21(2):165-9. doi: 10.1097/PAI.0b013e31825e00b7.

PMID:
22820662
[PubMed - indexed for MEDLINE]
2.

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.

Hum Pathol. 2007 Sep;38(9):1310-20. Epub 2007 Jun 6. Erratum in: Hum Pathol. 2008 Jan;39(1):147. Mellilo, Giovanni [corrected to Melillo, Giovanni].

PMID:
17555795
[PubMed - indexed for MEDLINE]
3.

Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.

Jensen RL, Gillespie D, House P, Layfield L, Shelton C.

J Neurosurg. 2004 Mar;100(3):488-97.

PMID:
15035285
[PubMed - indexed for MEDLINE]
4.

Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.

Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.

Cell Cycle. 2012 Dec 1;11(23):4462-73. doi: 10.4161/cc.22794. Epub 2012 Nov 16.

PMID:
23159849
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

PMID:
11431362
[PubMed - indexed for MEDLINE]
Free Article
6.
7.

Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma.

Lee S, Garner EI, Welch WR, Berkowitz RS, Mok SC.

Gynecol Oncol. 2007 Aug;106(2):311-7. Epub 2007 May 25.

PMID:
17532031
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Microtubular stability affects pVHL-mediated regulation of HIF-1alpha via the p38/MAPK pathway in hypoxic cardiomyocytes.

Teng M, Jiang XP, Zhang Q, Zhang JP, Zhang DX, Liang GP, Huang YS.

PLoS One. 2012;7(4):e35017. doi: 10.1371/journal.pone.0035017. Epub 2012 Apr 10.

PMID:
22506063
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Expression of VHL and HIF-1α and Their Clinicopathologic Significance in Benign and Malignant Lesions of the Gallbladder.

Yang Z, Yang Z, Xiong L, Huang S, Liu J, Yang L, Miao X.

Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):534-9. doi: 10.1097/PAI.0b013e318212f001.

PMID:
21415706
[PubMed - indexed for MEDLINE]
12.

Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.

Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER.

Cancer Res. 2002 Jul 1;62(13):3803-11.

PMID:
12097293
[PubMed - indexed for MEDLINE]
Free Article
13.

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.

Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.

BMC Cancer. 2012 Jul 17;12:293. doi: 10.1186/1471-2407-12-293.

PMID:
22804960
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma.

Gao YH, Li CX, Shen SM, Li H, Chen GQ, Wei Q, Wang LS.

Biochem Biophys Res Commun. 2013 May 24;435(1):46-51. doi: 10.1016/j.bbrc.2013.04.034. Epub 2013 Apr 20.

PMID:
23611775
[PubMed - indexed for MEDLINE]
15.

Regression of solid tumors by engineered overexpression of von Hippel-Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1alpha.

Sun X, Kanwar JR, Leung E, Vale M, Krissansen GW.

Gene Ther. 2003 Dec;10(25):2081-9.

PMID:
14595381
[PubMed - indexed for MEDLINE]
16.

[The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].

Gong K, Zhang N, Na X, Wu G, Yang XY, Xin DQ, Na YQ.

Zhonghua Wai Ke Za Zhi. 2005 Mar 15;43(6):390-3. Chinese.

PMID:
15854350
[PubMed - indexed for MEDLINE]
17.

Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.

Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.

J Biol Chem. 2012 Apr 27;287(18):14760-71. doi: 10.1074/jbc.M112.340232. Epub 2012 Feb 20.

PMID:
22351759
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

VHL genetic alteration in CCRCC does not determine de-regulation of HIF, CAIX, hnRNP A2/B1 and osteopontin.

Nyhan MJ, El Mashad SM, O'Donovan TR, Ahmad S, Collins C, Sweeney P, Rogers E, O'Sullivan GC, McKenna SL.

Cell Oncol (Dordr). 2011 Jun;34(3):225-34. doi: 10.1007/s13402-011-0029-5. Epub 2011 May 6.

PMID:
21547579
[PubMed - indexed for MEDLINE]
19.

Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression.

Périgny M, Hammel P, Corcos O, Larochelle O, Giraud S, Richard S, Sauvanet A, Belghiti J, Ruszniewski P, Bedossa P, Couvelard A.

Am J Surg Pathol. 2009 May;33(5):739-48. doi: 10.1097/PAS.0b013e3181967992.

PMID:
19238077
[PubMed - indexed for MEDLINE]
20.

STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.

Jung JE, Kim HS, Lee CS, Shin YJ, Kim YN, Kang GH, Kim TY, Juhnn YS, Kim SJ, Park JW, Ye SK, Chung MH.

Exp Mol Med. 2008 Oct 31;40(5):479-85.

PMID:
18985005
[PubMed - indexed for MEDLINE]
Free PMC Article

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