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Results: 1 to 20 of 139

1.

Aromatic residue mutations reveal direct correlation between HIV-1 nucleocapsid protein's nucleic acid chaperone activity and retroviral replication.

Wu H, Mitra M, McCauley MJ, Thomas JA, Rouzina I, Musier-Forsyth K, Williams MC, Gorelick RJ.

Virus Res. 2013 Feb;171(2):263-77. doi: 10.1016/j.virusres.2012.07.008. Epub 2012 Jul 16.

PMID:
22814429
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid protein's nucleic acid chaperone function.

Cruceanu M, Gorelick RJ, Musier-Forsyth K, Rouzina I, Williams MC.

J Mol Biol. 2006 Nov 10;363(5):867-77. Epub 2006 Aug 30.

PMID:
16997322
[PubMed - indexed for MEDLINE]
3.

Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replication.

Wu H, Mitra M, Naufer MN, McCauley MJ, Gorelick RJ, Rouzina I, Musier-Forsyth K, Williams MC.

Nucleic Acids Res. 2014 Feb;42(4):2525-37. doi: 10.1093/nar/gkt1227. Epub 2013 Nov 28.

PMID:
24293648
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Retroviral nucleocapsid proteins display nonequivalent levels of nucleic acid chaperone activity.

Stewart-Maynard KM, Cruceanu M, Wang F, Vo MN, Gorelick RJ, Williams MC, Rouzina I, Musier-Forsyth K.

J Virol. 2008 Oct;82(20):10129-42. doi: 10.1128/JVI.01169-08. Epub 2008 Aug 6.

PMID:
18684831
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Effect of Mg(2+) and Na(+) on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcription.

Vo MN, Barany G, Rouzina I, Musier-Forsyth K.

J Mol Biol. 2009 Feb 27;386(3):773-88. doi: 10.1016/j.jmb.2008.12.073. Epub 2009 Jan 6.

PMID:
19154740
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis.

Beltz H, Clauss C, Piémont E, Ficheux D, Gorelick RJ, Roques B, Gabus C, Darlix JL, de Rocquigny H, Mély Y.

J Mol Biol. 2005 May 20;348(5):1113-26. Epub 2005 Apr 1.

PMID:
15854648
[PubMed - indexed for MEDLINE]
7.

Specific zinc-finger architecture required for HIV-1 nucleocapsid protein's nucleic acid chaperone function.

Williams MC, Gorelick RJ, Musier-Forsyth K.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8614-9.

PMID:
12084921
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The N-terminal zinc finger and flanking basic domains represent the minimal region of the human immunodeficiency virus type-1 nucleocapsid protein for targeting chaperone function.

Mitra M, Wang W, Vo MN, Rouzina I, Barany G, Musier-Forsyth K.

Biochemistry. 2013 Nov 19;52(46):8226-36. doi: 10.1021/bi401250a. Epub 2013 Nov 6.

PMID:
24144434
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

C-terminal domain modulates the nucleic acid chaperone activity of human T-cell leukemia virus type 1 nucleocapsid protein via an electrostatic mechanism.

Qualley DF, Stewart-Maynard KM, Wang F, Mitra M, Gorelick RJ, Rouzina I, Williams MC, Musier-Forsyth K.

J Biol Chem. 2010 Jan 1;285(1):295-307. doi: 10.1074/jbc.M109.051334. Epub 2009 Nov 3.

PMID:
19887455
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Single aromatic residue location alters nucleic acid binding and chaperone function of FIV nucleocapsid protein.

Wu H, Wang W, Naiyer N, Fichtenbaum E, Qualley DF, McCauley MJ, Gorelick RJ, Rouzina I, Musier-Forsyth K, Williams MC.

Virus Res. 2014 Nov 26;193:39-51. doi: 10.1016/j.virusres.2014.06.002. Epub 2014 Jun 7.

PMID:
24915282
[PubMed - in process]
11.

HIV-1 nucleocapsid protein as a nucleic acid chaperone: spectroscopic study of its helix-destabilizing properties, structural binding specificity, and annealing activity.

Urbaneja MA, Wu M, Casas-Finet JR, Karpel RL.

J Mol Biol. 2002 May 3;318(3):749-64.

PMID:
12054820
[PubMed - indexed for MEDLINE]
12.

The conserved N-terminal basic residues and zinc-finger motifs of HIV-1 nucleocapsid restrict the viral cDNA synthesis during virus formation and maturation.

Didierlaurent L, Houzet L, Morichaud Z, Darlix JL, Mougel M.

Nucleic Acids Res. 2008 Aug;36(14):4745-53. doi: 10.1093/nar/gkn474. Epub 2008 Jul 18.

PMID:
18641038
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein.

Post K, Kankia B, Gopalakrishnan S, Yang V, Cramer E, Saladores P, Gorelick RJ, Guo J, Musier-Forsyth K, Levin JG.

Nucleic Acids Res. 2009 Apr;37(6):1755-66. doi: 10.1093/nar/gkn1045. Epub 2009 Jan 21.

PMID:
19158189
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Retrovirus-specific differences in matrix and nucleocapsid protein-nucleic acid interactions: implications for genomic RNA packaging.

Sun M, Grigsby IF, Gorelick RJ, Mansky LM, Musier-Forsyth K.

J Virol. 2014 Jan;88(2):1271-80. doi: 10.1128/JVI.02151-13. Epub 2013 Nov 13.

PMID:
24227839
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins.

Cruceanu M, Urbaneja MA, Hixson CV, Johnson DG, Datta SA, Fivash MJ, Stephen AG, Fisher RJ, Gorelick RJ, Casas-Finet JR, Rein A, Rouzina I, Williams MC.

Nucleic Acids Res. 2006 Jan 30;34(2):593-605. Print 2006.

PMID:
16449201
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Impact of the terminal bulges of HIV-1 cTAR DNA on its stability and the destabilizing activity of the nucleocapsid protein NCp7.

Beltz H, Azoulay J, Bernacchi S, Clamme JP, Ficheux D, Roques B, Darlix JL, Mély Y.

J Mol Biol. 2003 Apr 18;328(1):95-108.

PMID:
12684000
[PubMed - indexed for MEDLINE]
17.

Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: biological implications.

Wu T, Datta SA, Mitra M, Gorelick RJ, Rein A, Levin JG.

Virology. 2010 Sep 30;405(2):556-67. doi: 10.1016/j.virol.2010.06.042. Epub 2010 Jul 23.

PMID:
20655566
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Subtle alterations of the native zinc finger structures have dramatic effects on the nucleic acid chaperone activity of human immunodeficiency virus type 1 nucleocapsid protein.

Guo J, Wu T, Kane BF, Johnson DG, Henderson LE, Gorelick RJ, Levin JG.

J Virol. 2002 May;76(9):4370-8.

PMID:
11932404
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanism.

Levin JG, Guo J, Rouzina I, Musier-Forsyth K.

Prog Nucleic Acid Res Mol Biol. 2005;80:217-86. Review. No abstract available.

PMID:
16164976
[PubMed - indexed for MEDLINE]
20.

Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.

Dussupt V, Sette P, Bello NF, Javid MP, Nagashima K, Bouamr F.

J Virol. 2011 Mar;85(5):2304-15. doi: 10.1128/JVI.01562-10. Epub 2010 Dec 15.

PMID:
21159863
[PubMed - indexed for MEDLINE]
Free PMC Article
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