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Items: 1 to 20 of 103


Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing.

Dallas A, Ilves H, Ge Q, Kumar P, Shorenstein J, Kazakov SA, Cuellar TL, McManus MT, Behlke MA, Johnston BH.

Nucleic Acids Res. 2012 Oct;40(18):9255-71. doi: 10.1093/nar/gks662. Epub 2012 Jul 18.


Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity.

Ge Q, Ilves H, Dallas A, Kumar P, Shorenstein J, Kazakov SA, Johnston BH.

RNA. 2010 Jan;16(1):106-17. doi: 10.1261/rna.1894510. Epub 2009 Dec 1.


Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs.

Ge Q, Dallas A, Ilves H, Shorenstein J, Behlke MA, Johnston BH.

RNA. 2010 Jan;16(1):118-30. doi: 10.1261/rna.1901810. Epub 2009 Nov 30.


Design and chemical modification of synthetic short shRNAs as potent RNAi triggers.

Dallas A, Johnston BH.

Methods Mol Biol. 2013;942:279-90. doi: 10.1007/978-1-62703-119-6_15.


Dicer-independent processing of short hairpin RNAs.

Liu YP, Schopman NC, Berkhout B.

Nucleic Acids Res. 2013 Apr 1;41(6):3723-33. doi: 10.1093/nar/gkt036. Epub 2013 Feb 1.


Loop-miRs: active microRNAs generated from single-stranded loop regions.

Winter J, Link S, Witzigmann D, Hildenbrand C, Previti C, Diederichs S.

Nucleic Acids Res. 2013 May 1;41(10):5503-12. doi: 10.1093/nar/gkt251. Epub 2013 Apr 10.


Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R.

Cell. 2005 Nov 18;123(4):631-40. Epub 2005 Nov 3.


A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.

Maniataki E, Mourelatos Z.

Genes Dev. 2005 Dec 15;19(24):2979-90.


Intertwined pathways for Argonaute-mediated microRNA biogenesis in Drosophila.

Yang JS, Smibert P, Westholm JO, Jee D, Maurin T, Lai EC.

Nucleic Acids Res. 2014 Feb;42(3):1987-2002. doi: 10.1093/nar/gkt1038. Epub 2013 Nov 12.


Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes.

Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD.

Cell. 2005 Nov 18;123(4):607-20. Epub 2005 Nov 3.


The N domain of Argonaute drives duplex unwinding during RISC assembly.

Kwak PB, Tomari Y.

Nat Struct Mol Biol. 2012 Jan 10;19(2):145-51. doi: 10.1038/nsmb.2232.


Sorting of Drosophila small silencing RNAs.

Tomari Y, Du T, Zamore PD.

Cell. 2007 Jul 27;130(2):299-308.


Slicer function of Drosophila Argonautes and its involvement in RISC formation.

Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC.

Genes Dev. 2005 Dec 1;19(23):2837-48. Epub 2005 Nov 14.


Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways.

Okamura K, Ishizuka A, Siomi H, Siomi MC.

Genes Dev. 2004 Jul 15;18(14):1655-66. Epub 2004 Jul 1.


Molecular mechanisms of RNA interference.

Wilson RC, Doudna JA.

Annu Rev Biophys. 2013;42:217-39. doi: 10.1146/annurev-biophys-083012-130404. Review.


Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.

Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD.

Nat Struct Mol Biol. 2009 Dec;16(12):1259-66. doi: 10.1038/nsmb.1712. Epub 2009 Nov 29.


Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes.

Kim K, Lee YS, Carthew RW.

RNA. 2007 Jan;13(1):22-9. Epub 2006 Nov 22.


The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo.

Gu S, Jin L, Zhang Y, Huang Y, Zhang F, Valdmanis PN, Kay MA.

Cell. 2012 Nov 9;151(4):900-11. doi: 10.1016/j.cell.2012.09.042.


Hierarchical rules for Argonaute loading in Drosophila.

Czech B, Zhou R, Erlich Y, Brennecke J, Binari R, Villalta C, Gordon A, Perrimon N, Hannon GJ.

Mol Cell. 2009 Nov 13;36(3):445-56. doi: 10.1016/j.molcel.2009.09.028.

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