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Items: 1 to 20 of 81

1.

On the Pro-Metastatic Stress Response to Cancer Therapies: Evidence for a Positive Co-Operation between TIMP-1, HIF-1α, and miR-210.

Cui H, Grosso S, Schelter F, Mari B, Krüger A.

Front Pharmacol. 2012 Jul 12;3:134. doi: 10.3389/fphar.2012.00134. eCollection 2012.

2.

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α.

Schelter F, Halbgewachs B, Bäumler P, Neu C, Görlach A, Schrötzlmair F, Krüger A.

Clin Exp Metastasis. 2011 Feb;28(2):91-9. doi: 10.1007/s10585-010-9360-x. Epub 2010 Oct 30.

PMID:
21053058
3.

Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes.

Cui H, Seubert B, Stahl E, Dietz H, Reuning U, Moreno-Leon L, Ilie M, Hofman P, Nagase H, Mari B, Krüger A.

Oncogene. 2015 Jul;34(28):3640-50. doi: 10.1038/onc.2014.300. Epub 2014 Sep 29.

PMID:
25263437
4.

Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer.

Bendinelli P, Maroni P, Matteucci E, Luzzati A, Perrucchini G, Desiderio MA.

Eur J Cancer. 2013 Jul;49(11):2608-18. doi: 10.1016/j.ejca.2013.03.002. Epub 2013 Apr 6.

PMID:
23566416
5.

MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis.

Cha ST, Chen PS, Johansson G, Chu CY, Wang MY, Jeng YM, Yu SL, Chen JS, Chang KJ, Jee SH, Tan CT, Lin MT, Kuo ML.

Cancer Res. 2010 Apr 1;70(7):2675-85. doi: 10.1158/0008-5472.CAN-09-2448. Epub 2010 Mar 16.

6.

Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line.

Schelter F, Gerg M, Halbgewachs B, Schaten S, Görlach A, Schrötzlmair F, Krüger A.

J Biol Chem. 2010 Aug 20;285(34):26182-9. doi: 10.1074/jbc.M110.140608. Epub 2010 Jun 21.

7.

Nuclear co-localization and functional interaction of COX-2 and HIF-1α characterize bone metastasis of human breast carcinoma.

Maroni P, Matteucci E, Luzzati A, Perrucchini G, Bendinelli P, Desiderio MA.

Breast Cancer Res Treat. 2011 Sep;129(2):433-50. doi: 10.1007/s10549-010-1240-1. Epub 2010 Nov 11.

PMID:
21069452
8.

MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta.

Cao P, Deng Z, Wan M, Huang W, Cramer SD, Xu J, Lei M, Sui G.

Mol Cancer. 2010 May 17;9:108. doi: 10.1186/1476-4598-9-108.

9.

Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells.

Mace TA, Collins AL, Wojcik SE, Croce CM, Lesinski GB, Bloomston M.

J Surg Res. 2013 Oct;184(2):855-60. doi: 10.1016/j.jss.2013.04.061. Epub 2013 May 18.

10.

Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.

Fujiwara S, Nakagawa K, Harada H, Nagato S, Furukawa K, Teraoka M, Seno T, Oka K, Iwata S, Ohnishi T.

Int J Oncol. 2007 Apr;30(4):793-802.

PMID:
17332917
11.

Hypoxia-inducible factor-1 in human breast and prostate cancer.

Kimbro KS, Simons JW.

Endocr Relat Cancer. 2006 Sep;13(3):739-49. Review.

12.

A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes.

Liu Y, Nie H, Zhang K, Ma D, Yang G, Zheng Z, Liu K, Yu B, Zhai C, Yang S.

FEBS Lett. 2014 Aug 25;588(17):3137-46. doi: 10.1016/j.febslet.2014.05.067. Epub 2014 Jun 28.

13.

Differential distribution of miR-20a and miR-20b may underly metastatic heterogeneity of breast cancers.

Li JY, Zhang Y, Zhang WH, Jia S, Kang Y, Zhu XY.

Asian Pac J Cancer Prev. 2012;13(5):1901-6.

14.

Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1α in cancer cells.

Zhu S, Zhou Y, Wang L, Zhang J, Wu H, Xiong J, Zhang J, Tian Y, Wang C, Wu H.

Mol Carcinog. 2011 Oct;50(10):770-80. doi: 10.1002/mc.20678. Epub 2011 Jul 12.

PMID:
21751260
15.

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).

De Francesco EM, Lappano R, Santolla MF, Marsico S, Caruso A, Maggiolini M.

Breast Cancer Res. 2013;15(4):R64.

16.

HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.

Marín-Hernández A, Gallardo-Pérez JC, Ralph SJ, Rodríguez-Enríquez S, Moreno-Sánchez R.

Mini Rev Med Chem. 2009 Aug;9(9):1084-101. Review.

PMID:
19689405
17.

Downregulation of TIMP2 via HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma.

Kai AK, Chan LK, Lo RC, Lee JM, Wong CC, Wong JC, Ng IO.

Hepatology. 2016 Mar 28. doi: 10.1002/hep.28577. [Epub ahead of print]

PMID:
27018975
18.

Elevated expression of thymosin β4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1α in early-stage cervical cancers.

Kim NS, Kang YJ, Jo JO, Kim HY, Oh YR, Kim YO, Jung MH, Ock MS, Cha HJ.

Pathol Oncol Res. 2011 Sep;17(3):493-502. doi: 10.1007/s12253-010-9327-x. Epub 2011 Jan 7.

PMID:
21213129
19.

Maslinic acid inhibits the metastatic capacity of DU145 human prostate cancer cells: possible mediation via hypoxia-inducible factor-1α signalling.

Park SY, Nho CW, Kwon DY, Kang YH, Lee KW, Park JH.

Br J Nutr. 2013 Jan 28;109(2):210-22. doi: 10.1017/S0007114512000967. Epub 2012 Apr 13.

PMID:
22716951
20.

Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner.

Miyoshi A, Kitajima Y, Ide T, Ohtaka K, Nagasawa H, Uto Y, Hori H, Miyazaki K.

Int J Oncol. 2006 Dec;29(6):1533-9.

PMID:
17088993
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