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Results: 1 to 20 of 91

1.

Antitumor activity of novel chimeric peptides derived from cyclinD/CDK4 and the protein transduction domain 4.

Wang H, Chen X, Chen Y, Sun L, Li G, Zhai M, Zhai W, Kang Q, Gao Y, Qi Y.

Amino Acids. 2013 Feb;44(2):499-510. doi: 10.1007/s00726-012-1360-5. Epub 2012 Jul 17.

PMID:
22802137
[PubMed - indexed for MEDLINE]
2.

Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis.

Tsai SL, Suk FM, Wang CI, Liu DZ, Hou WC, Lin PJ, Hung LF, Liang YC.

Biochem Pharmacol. 2007 Dec 3;74(11):1575-86. Epub 2007 Aug 11.

PMID:
17869226
[PubMed - indexed for MEDLINE]
3.

A novel peptide from alpha5 helix of Asterina pectinifera cyclin B conjugated to HIV-Tat(49-57) with cytotoxic and apoptotic effects against human cancer cells.

Lou H, Gao Y, Zhai M, Qi Y, Chen L, Lv H, Yu J, Li Y.

Bioorg Med Chem Lett. 2008 Aug 15;18(16):4633-7. doi: 10.1016/j.bmcl.2008.07.017. Epub 2008 Jul 10.

PMID:
18656352
[PubMed - indexed for MEDLINE]
4.

Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.

Kan WL, Yin C, Xu HX, Xu G, To KK, Cho CH, Rudd JA, Lin G.

Int J Cancer. 2013 Feb 1;132(3):707-16. doi: 10.1002/ijc.27694. Epub 2012 Jul 11.

PMID:
22733377
[PubMed - indexed for MEDLINE]
5.

In vitro antitumor properties of a novel cyclin-dependent kinase inhibitor, P276-00.

Joshi KS, Rathos MJ, Joshi RD, Sivakumar M, Mascarenhas M, Kamble S, Lal B, Sharma S.

Mol Cancer Ther. 2007 Mar;6(3):918-25.

PMID:
17363486
[PubMed - indexed for MEDLINE]
Free Article
6.

Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).

Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.

Clin Cancer Res. 2002 Nov;8(11):3549-60.

PMID:
12429646
[PubMed - indexed for MEDLINE]
Free Article
7.

Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells.

Sacco E, Metalli D, Spinelli M, Manzoni R, Samalikova M, Grandori R, Morrione A, Traversa S, Alberghina L, Vanoni M.

Biotechnol Adv. 2012 Jan-Feb;30(1):233-43. doi: 10.1016/j.biotechadv.2011.05.011. Epub 2011 May 18.

PMID:
21620943
[PubMed - indexed for MEDLINE]
8.

Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule.

Fåhraeus R, Laín S, Ball KL, Lane DP.

Oncogene. 1998 Feb 5;16(5):587-96.

PMID:
9482104
[PubMed - indexed for MEDLINE]
Free Article
9.

Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.

Warenius HM, Kilburn JD, Essex JW, Maurer RI, Blaydes JP, Agarwala U, Seabra LA.

Mol Cancer. 2011 Jun 13;10:72. doi: 10.1186/1476-4598-10-72.

PMID:
21668989
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials.

DePinto W, Chu XJ, Yin X, Smith M, Packman K, Goelzer P, Lovey A, Chen Y, Qian H, Hamid R, Xiang Q, Tovar C, Blain R, Nevins T, Higgins B, Luistro L, Kolinsky K, Felix B, Hussain S, Heimbrook D.

Mol Cancer Ther. 2006 Nov;5(11):2644-58.

PMID:
17121911
[PubMed - indexed for MEDLINE]
Free Article
11.

Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules.

Kuriyama S, Hitomi M, Yoshiji H, Nonomura T, Tsujimoto T, Mitoro A, Akahane T, Ogawa M, Nakai S, Deguchi A, Masaki T, Uchida N.

Int J Oncol. 2005 Aug;27(2):505-11.

PMID:
16010434
[PubMed - indexed for MEDLINE]
12.

Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy.

Shimura T, Kakuda S, Ochiai Y, Kuwahara Y, Takai Y, Fukumoto M.

Int J Radiat Oncol Biol Phys. 2011 Jun 1;80(2):540-8. doi: 10.1016/j.ijrobp.2010.12.065. Epub 2011 Mar 11.

PMID:
21398050
[PubMed - indexed for MEDLINE]
13.

Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes.

Tin AS, Sundar SN, Tran KQ, Park AH, Poindexter KM, Firestone GL.

Anticancer Drugs. 2012 Apr;23(4):370-9. doi: 10.1097/CAD.0b013e32834f6ea8.

PMID:
22185819
[PubMed - indexed for MEDLINE]
14.

Adenosine induces cell cycle arrest and apoptosis via cyclinD1/Cdk4 and Bcl-2/Bax pathways in human ovarian cancer cell line OVCAR-3.

Shirali S, Aghaei M, Shabani M, Fathi M, Sohrabi M, Moeinifard M.

Tumour Biol. 2013 Apr;34(2):1085-95. doi: 10.1007/s13277-013-0650-1. Epub 2013 Jan 24.

PMID:
23345014
[PubMed - indexed for MEDLINE]
15.

Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression.

Grillo M, Bott MJ, Khandke N, McGinnis JP, Miranda M, Meyyappan M, Rosfjord EC, Rabindran SK.

Breast Cancer Res Treat. 2006 Jan;95(2):185-94. Epub 2005 Dec 1.

PMID:
16319987
[PubMed - indexed for MEDLINE]
16.

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes.

Solvason N, Wu WW, Kabra N, Wu X, Lees E, Howard MC.

J Exp Med. 1996 Aug 1;184(2):407-17.

PMID:
8760794
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.

Wang YJ, Jeng JH, Chen RJ, Tseng H, Chen LC, Liang YC, Lin CH, Chen CH, Chu JS, Ho WL, Ho YS.

Mol Carcinog. 2002 Aug;34(4):199-210.

PMID:
12203371
[PubMed - indexed for MEDLINE]
19.
20.

Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.

Patel V, Senderowicz AM, Pinto D Jr, Igishi T, Raffeld M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS.

J Clin Invest. 1998 Nov 1;102(9):1674-81.

PMID:
9802881
[PubMed - indexed for MEDLINE]
Free PMC Article

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