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Results: 1 to 20 of 86

1.

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.

Montagner M, Enzo E, Forcato M, Zanconato F, Parenti A, Rampazzo E, Basso G, Leo G, Rosato A, Bicciato S, Cordenonsi M, Piccolo S.

Nature. 2012 Jul 19;487(7407):380-4. doi: 10.1038/nature11207.

PMID:
22801492
[PubMed - indexed for MEDLINE]
2.

p63, Sharp1, and HIFs: master regulators of metastasis in triple-negative breast cancer.

Piccolo S, Enzo E, Montagner M.

Cancer Res. 2013 Aug 15;73(16):4978-81. doi: 10.1158/0008-5472.CAN-13-0962. Epub 2013 Aug 2. Review.

PMID:
23913939
[PubMed - indexed for MEDLINE]
Free Article
4.

Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer.

Helczynska K, Larsson AM, Holmquist Mengelbier L, Bridges E, Fredlund E, Borgquist S, Landberg G, Påhlman S, Jirström K.

Cancer Res. 2008 Nov 15;68(22):9212-20. doi: 10.1158/0008-5472.CAN-08-1135.

PMID:
19010893
[PubMed - indexed for MEDLINE]
Free Article
6.

Hypoxia induced CCR7 expression via HIF-1alpha and HIF-2alpha correlates with migration and invasion in lung cancer cells.

Li Y, Qiu X, Zhang S, Zhang Q, Wang E.

Cancer Biol Ther. 2009 Feb;8(4):322-30. Epub 2009 Feb 3.

PMID:
19305150
[PubMed - indexed for MEDLINE]
Free Article
7.

The HIF pathway: implications for patterns of gene expression in cancer.

Wykoff CC, Pugh CW, Harris AL, Maxwell PH, Ratcliffe PJ.

Novartis Found Symp. 2001;240:212-25; discussion 225-31. Review.

PMID:
11727931
[PubMed - indexed for MEDLINE]
8.
9.

The "Sharp" blade against HIF-mediated metastasis.

Amelio I, Melino G.

Cell Cycle. 2012 Dec 15;11(24):4530-5. doi: 10.4161/cc.22820. Epub 2012 Nov 27.

PMID:
23187809
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms.

Higashimura Y, Terai T, Yamaji R, Mitani T, Ogawa M, Harada N, Inui H, Nakano Y.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):201-5. doi: 10.1016/j.bbrc.2011.08.058. Epub 2011 Aug 24.

PMID:
21888897
[PubMed - indexed for MEDLINE]
11.

Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients.

Peurala E, Koivunen P, Bloigu R, Haapasaari KM, Jukkola-Vuorinen A.

Breast Cancer Res Treat. 2012 May;133(1):179-88. doi: 10.1007/s10549-011-1750-5. Epub 2011 Aug 30.

PMID:
21877141
[PubMed - indexed for MEDLINE]
12.

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.

Hum Pathol. 2007 Sep;38(9):1310-20. Epub 2007 Jun 6. Erratum in: Hum Pathol. 2008 Jan;39(1):147. Mellilo, Giovanni [corrected to Melillo, Giovanni].

PMID:
17555795
[PubMed - indexed for MEDLINE]
13.

Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.

Park SS, Bae I, Lee YJ.

J Cell Biochem. 2008 Apr 15;103(6):1989-98.

PMID:
17973296
[PubMed - indexed for MEDLINE]
14.

Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha.

Yuan Y, Hilliard G, Ferguson T, Millhorn DE.

J Biol Chem. 2003 May 2;278(18):15911-6. Epub 2003 Feb 26.

PMID:
12606543
[PubMed - indexed for MEDLINE]
Free Article
15.

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha.

van Hagen M, Overmeer RM, Abolvardi SS, Vertegaal AC.

Nucleic Acids Res. 2010 Apr;38(6):1922-31. doi: 10.1093/nar/gkp1157. Epub 2009 Dec 21.

PMID:
20026589
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

Aprelikova O, Wood M, Tackett S, Chandramouli GV, Barrett JC.

Cancer Res. 2006 Jun 1;66(11):5641-7.

PMID:
16740701
[PubMed - indexed for MEDLINE]
Free Article
17.

Mammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL-independent regulation.

Chen L, Uchida K, Endler A, Shibasaki F.

J Biol Chem. 2007 Apr 27;282(17):12707-16. Epub 2007 Feb 26.

PMID:
17324924
[PubMed - indexed for MEDLINE]
Free Article
18.

Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.

Xu J, Wang B, Xu Y, Sun L, Tian W, Shukla D, Barod R, Grillari J, Grillari-Voglauer R, Maxwell PH, Esteban MA.

Oncogene. 2012 Feb 23;31(8):1065-72. doi: 10.1038/onc.2011.305. Epub 2011 Aug 15.

PMID:
21841824
[PubMed - indexed for MEDLINE]
19.

Thymosin β4 expression correlates with lymph node metastasis through hypoxia inducible factor-α induction in breast cancer.

Yoon SY, Lee HR, Park Y, Kim JH, Kim SY, Yoon SR, Lee WJ, Cho BJ, Min H, Bang JW, Park H, Bang SI, Cho D.

Oncol Rep. 2011 Jan;25(1):23-31.

PMID:
21109953
[PubMed - indexed for MEDLINE]

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