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Results: 1 to 20 of 184

1.

AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells.

Raghavan P, Tumati V, Yu L, Chan N, Tomimatsu N, Burma S, Bristow RG, Saha D.

Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e507-14. doi: 10.1016/j.ijrobp.2012.05.035. Epub 2012 Jul 12.

PMID:
22795803
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.

Byth KF, Thomas A, Hughes G, Forder C, McGregor A, Geh C, Oakes S, Green C, Walker M, Newcombe N, Green S, Growcott J, Barker A, Wilkinson RW.

Mol Cancer Ther. 2009 Jul;8(7):1856-66. doi: 10.1158/1535-7163.MCT-08-0836. Epub 2009 Jun 9.

PMID:
19509270
[PubMed - indexed for MEDLINE]
Free Article
3.

Effect of PF-02341066 and radiation on non-small cell lung cancer cells.

Tumati V, Kumar S, Yu L, Chen B, Choy H, Saha D.

Oncol Rep. 2013 Mar;29(3):1094-100. doi: 10.3892/or.2012.2198. Epub 2012 Dec 18.

PMID:
23254764
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells.

Kodym E, Kodym R, Reis AE, Habib AA, Story MD, Saha D.

Lung Cancer. 2009 Oct;66(1):37-47. doi: 10.1016/j.lungcan.2008.12.026. Epub 2009 Feb 3.

PMID:
19193471
[PubMed - indexed for MEDLINE]
5.

Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation.

Zhang T, Cui GB, Zhang J, Zhang F, Zhou YA, Jiang T, Li XF.

Oncol Rep. 2010 Dec;24(6):1683-9.

PMID:
21042768
[PubMed - indexed for MEDLINE]
6.

Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines.

Iwasa T, Okamoto I, Suzuki M, Nakahara T, Yamanaka K, Hatashita E, Yamada Y, Fukuoka M, Ono K, Nakagawa K.

Clin Cancer Res. 2008 Oct 15;14(20):6496-504. doi: 10.1158/1078-0432.CCR-08-0468.

PMID:
18927289
[PubMed - indexed for MEDLINE]
Free Article
7.

Epothilone B confers radiation dose enhancement in DAB2IP gene knock-down radioresistant prostate cancer cells.

Kong Z, Raghavan P, Xie D, Boike T, Burma S, Chen D, Chakraborty A, Hsieh JT, Saha D.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1210-8. doi: 10.1016/j.ijrobp.2010.06.019.

PMID:
20970033
[PubMed - indexed for MEDLINE]
8.

Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells.

Zhang F, Zhang T, Teng ZH, Zhang R, Wang JB, Mei QB.

Cancer Biol Ther. 2009 May;8(9):823-31. Epub 2009 May 10.

PMID:
19270532
[PubMed - indexed for MEDLINE]
Free Article
9.

In vitro and in vivo radiosensitization with AZD6244 (ARRY-142886), an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 kinase.

Chung EJ, Brown AP, Asano H, Mandler M, Burgan WE, Carter D, Camphausen K, Citrin D.

Clin Cancer Res. 2009 May 1;15(9):3050-7. doi: 10.1158/1078-0432.CCR-08-2954. Epub 2009 Apr 14.

PMID:
19366835
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.

Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B.

Clin Cancer Res. 2009 Oct 1;15(19):6096-105. doi: 10.1158/1078-0432.CCR-09-0589. Epub 2009 Sep 22.

PMID:
19773376
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Flavopiridol, a cyclin-dependent kinase inhibitor, enhances radiosensitivity of ovarian carcinoma cells.

Raju U, Nakata E, Mason KA, Ang KK, Milas L.

Cancer Res. 2003 Jun 15;63(12):3263-7.

PMID:
12810657
[PubMed - indexed for MEDLINE]
Free Article
13.

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

Toulany M, Kehlbach R, Florczak U, Sak A, Wang S, Chen J, Lobrich M, Rodemann HP.

Mol Cancer Ther. 2008 Jul;7(7):1772-81. doi: 10.1158/1535-7163.MCT-07-2200.

PMID:
18644989
[PubMed - indexed for MEDLINE]
Free Article
14.

PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells.

Kim W, Youn H, Kwon T, Kang J, Kim E, Son B, Yang HJ, Jung Y, Youn B.

Pharmacol Res. 2013 Apr;70(1):90-101. doi: 10.1016/j.phrs.2013.01.005. Epub 2013 Jan 23.

PMID:
23352980
[PubMed - indexed for MEDLINE]
15.

The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells.

Hayman TJ, Wahba A, Rath BH, Bae H, Kramp T, Shankavaram UT, Camphausen K, Tofilon PJ.

Clin Cancer Res. 2014 Jan 1;20(1):110-9. doi: 10.1158/1078-0432.CCR-13-2136. Epub 2013 Nov 6.

PMID:
24198241
[PubMed - indexed for MEDLINE]
16.

Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft.

Senra JM, Telfer BA, Cherry KE, McCrudden CM, Hirst DG, O'Connor MJ, Wedge SR, Stratford IJ.

Mol Cancer Ther. 2011 Oct;10(10):1949-58. doi: 10.1158/1535-7163.MCT-11-0278. Epub 2011 Aug 8.

PMID:
21825006
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Histone deacetylase inhibitor NVP-LAQ824 sensitizes human nonsmall cell lung cancer to the cytotoxic effects of ionizing radiation.

Cuneo KC, Fu A, Osusky K, Huamani J, Hallahan DE, Geng L.

Anticancer Drugs. 2007 Aug;18(7):793-800.

PMID:
17581301
[PubMed - indexed for MEDLINE]
18.

Inhibition of insulin-like growth factor 1 receptor by CP-751,871 radiosensitizes non-small cell lung cancer cells.

Iwasa T, Okamoto I, Suzuki M, Hatashita E, Yamada Y, Fukuoka M, Ono K, Nakagawa K.

Clin Cancer Res. 2009 Aug 15;15(16):5117-25. doi: 10.1158/1078-0432.CCR-09-0478. Epub 2009 Aug 11.

PMID:
19671857
[PubMed - indexed for MEDLINE]
Free Article
19.

Targeting epidermal growth factor receptor-associated signaling pathways in non-small cell lung cancer cells: implication in radiation response.

Choi EJ, Ryu YK, Kim SY, Wu HG, Kim JS, Kim IH, Kim IA.

Mol Cancer Res. 2010 Jul;8(7):1027-36. doi: 10.1158/1541-7786.MCR-09-0507. Epub 2010 Jun 29.

PMID:
20587532
[PubMed - indexed for MEDLINE]
Free Article
20.

Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.

Nagata Y, Takahashi A, Ohnishi K, Ota I, Ohnishi T, Tojo T, Taniguchi S.

Int J Oncol. 2010 Oct;37(4):1001-10.

PMID:
20811722
[PubMed - indexed for MEDLINE]

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