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Results: 1 to 20 of 97

1.

Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation.

Pan CC, Bloodworth JC, Mythreye K, Lee NY.

Biochem Biophys Res Commun. 2012 Aug 3;424(3):620-3. doi: 10.1016/j.bbrc.2012.06.163. Epub 2012 Jul 10.

PMID:
22789855
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells.

Lee NY, Blobe GC.

J Biol Chem. 2007 Jul 20;282(29):21507-17. Epub 2007 May 31.

PMID:
17540773
[PubMed - indexed for MEDLINE]
Free Article
3.

Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

Lee NY, Ray B, How T, Blobe GC.

J Biol Chem. 2008 Nov 21;283(47):32527-33. doi: 10.1074/jbc.M803059200. Epub 2008 Sep 5.

PMID:
18775991
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways.

Park S, Dimaio TA, Liu W, Wang S, Sorenson CM, Sheibani N.

J Cell Sci. 2013 Mar 15;126(Pt 6):1392-405. doi: 10.1242/jcs.117275. Epub 2013 Feb 15.

PMID:
23418351
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury.

Botella LM, Sánchez-Elsner T, Sanz-Rodriguez F, Kojima S, Shimada J, Guerrero-Esteo M, Cooreman MP, Ratziu V, Langa C, Vary CP, Ramirez JR, Friedman S, Bernabéu C.

Blood. 2002 Dec 1;100(12):4001-10.

PMID:
12433697
[PubMed - indexed for MEDLINE]
Free Article
6.

Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis.

Lee NY, Golzio C, Gatza CE, Sharma A, Katsanis N, Blobe GC.

Mol Biol Cell. 2012 Jul;23(13):2412-23. doi: 10.1091/mbc.E11-12-0993. Epub 2012 May 16.

PMID:
22593212
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

Lebrin F, Goumans MJ, Jonker L, Carvalho RL, Valdimarsdottir G, Thorikay M, Mummery C, Arthur HM, ten Dijke P.

EMBO J. 2004 Oct 13;23(20):4018-28. Epub 2004 Sep 23.

PMID:
15385967
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways.

Sánchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabéu C.

J Biol Chem. 2002 Nov 15;277(46):43799-808. Epub 2002 Sep 11.

PMID:
12228247
[PubMed - indexed for MEDLINE]
Free Article
9.

Synergy between anti-endoglin (CD105) monoclonal antibodies and TGF-beta in suppression of growth of human endothelial cells.

She X, Matsuno F, Harada N, Tsai H, Seon BK.

Int J Cancer. 2004 Jan 10;108(2):251-7.

PMID:
14639611
[PubMed - indexed for MEDLINE]
10.

S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology.

Blanco FJ, Grande MT, Langa C, Oujo B, Velasco S, Rodriguez-Barbero A, Perez-Gomez E, Quintanilla M, López-Novoa JM, Bernabeu C.

Circ Res. 2008 Dec 5;103(12):1383-92. doi: 10.1161/CIRCRESAHA.108.176552. Epub 2008 Oct 30.

PMID:
18974388
[PubMed - indexed for MEDLINE]
Free Article
11.

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells.

Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC.

EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31.

PMID:
22940691
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Endoglin modulates cellular responses to TGF-beta 1.

Lastres P, Letamendía A, Zhang H, Rius C, Almendro N, Raab U, López LA, Langa C, Fabra A, Letarte M, Bernabéu C.

J Cell Biol. 1996 Jun;133(5):1109-21.

PMID:
8655583
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration.

Ma X, Labinaz M, Goldstein J, Miller H, Keon WJ, Letarte M, O'Brien E.

Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2546-52.

PMID:
11116051
[PubMed - indexed for MEDLINE]
Free Article
14.

Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-beta signaling pathway.

Fernández-L A, Sanz-Rodriguez F, Blanco FJ, Bernabéu C, Botella LM.

Clin Med Res. 2006 Mar;4(1):66-78. Review.

PMID:
16595794
[PubMed - indexed for MEDLINE]
Free PMC Article
15.
16.

Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.

Kumar S, Pan CC, Bloodworth JC, Nixon AB, Theuer C, Hoyt DG, Lee NY.

Oncogene. 2014 Jul 24;33(30):3970-9. doi: 10.1038/onc.2013.386. Epub 2013 Sep 30.

PMID:
24077288
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Thrombin induces endocytosis of endoglin and type-II TGF-beta receptor and down-regulation of TGF-beta signaling in endothelial cells.

Tang H, Low B, Rutherford SA, Hao Q.

Blood. 2005 Mar 1;105(5):1977-85. Epub 2004 Nov 2.

PMID:
15522964
[PubMed - indexed for MEDLINE]
Free Article
18.

Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling.

Hough C, Radu M, Doré JJ.

PLoS One. 2012;7(8):e42513. doi: 10.1371/journal.pone.0042513. Epub 2012 Aug 6.

PMID:
22880011
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex.

Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C.

J Cell Physiol. 2005 Aug;204(2):574-84.

PMID:
15702480
[PubMed - indexed for MEDLINE]
20.

The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras.

Santibanez JF, Pérez-Gómez E, Fernandez-L A, Garrido-Martin EM, Carnero A, Malumbres M, Vary CP, Quintanilla M, Bernabéu C.

Carcinogenesis. 2010 Dec;31(12):2145-54. doi: 10.1093/carcin/bgq199. Epub 2010 Sep 30.

PMID:
20884686
[PubMed - indexed for MEDLINE]
Free Article

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