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Items: 1 to 20 of 140

1.

IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis.

Kobayashi T, Matsuoka K, Sheikh SZ, Russo SM, Mishima Y, Collins C, deZoeten EF, Karp CL, Ting JP, Sartor RB, Plevy SE.

J Immunol. 2012 Aug 15;189(4):1792-9. doi: 10.4049/jimmunol.1200042. Epub 2012 Jul 11.

2.

NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity.

Kobayashi T, Matsuoka K, Sheikh SZ, Elloumi HZ, Kamada N, Hisamatsu T, Hansen JJ, Doty KR, Pope SD, Smale ST, Hibi T, Rothman PB, Kashiwada M, Plevy SE.

J Immunol. 2011 Apr 15;186(8):4649-55. doi: 10.4049/jimmunol.1003888. Epub 2011 Mar 7.

3.

A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis.

Elloumi HZ, Maharshak N, Rao KN, Kobayashi T, Ryu HS, Mühlbauer M, Li F, Jobin C, Plevy SE.

PLoS One. 2012;7(3):e34172. doi: 10.1371/journal.pone.0034172. Epub 2012 Mar 27.

4.

Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.

Zhou D, Collins CA, Wu P, Brown EJ.

J Leukoc Biol. 2010 May;87(5):845-55. doi: 10.1189/jlb.0409289. Epub 2010 Feb 9.

5.

Iκb-ζ plays an important role in the ERK-dependent dysregulation of malaria parasite GPI-induced IL-12 expression.

Zhu J, Weinberg R, Wu X, Gowda NM, Muta T, Gowda DC.

IUBMB Life. 2012 Feb;64(2):187-93. doi: 10.1002/iub.592. Epub 2011 Nov 30.

6.

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CG, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M, Snyder A, Giacomin PR, Joyce KL, Hoang TB, Bewtra M, Brodsky IE, Sonnenberg GF, Bushman FD, Won KJ, Lazar MA, Artis D.

Nature. 2013 Dec 5;504(7478):153-7. doi: 10.1038/nature12687. Epub 2013 Nov 3.

7.

Klf10 inhibits IL-12p40 production in macrophage colony-stimulating factor-induced mouse bone marrow-derived macrophages.

Zhang W, Wang X, Xia X, Liu X, Suo S, Guo J, Li M, Cao W, Cai Z, Hui Z, Subramaniam M, Spelsberg TC, Wang J, Wang L.

Eur J Immunol. 2013 Jan;43(1):258-69. doi: 10.1002/eji.201242697. Epub 2012 Nov 27.

8.

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment.

Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, Sweet MJ, Dalpke AH.

Immunology. 2007 Dec;122(4):596-606. Epub 2007 Jul 16.

9.

Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription.

Zhang X, Edwards JP, Mosser DM.

J Immunol. 2006 Jul 15;177(2):1282-8.

10.

Interleukin-12 p40 promoter activity is regulated by the reversible acetylation mediated by HDAC1 and p300.

Lu J, Sun H, Wang X, Liu C, Xu X, Li F, Huang B.

Cytokine. 2005 Jul 7;31(1):46-51.

PMID:
15869883
11.

Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis.

Sheikh SZ, Matsuoka K, Kobayashi T, Li F, Rubinas T, Plevy SE.

J Immunol. 2010 Apr 15;184(8):4069-73. doi: 10.4049/jimmunol.0903600. Epub 2010 Mar 12.

13.

Histone deacetylation inhibits IL4 gene expression in T cells.

Valapour M, Guo J, Schroeder JT, Keen J, Cianferoni A, Casolaro V, Georas SN.

J Allergy Clin Immunol. 2002 Feb;109(2):238-45.

PMID:
11842291
14.

Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages.

Han SB, Lee JK.

Arch Pharm Res. 2009 Apr;32(4):613-24. doi: 10.1007/s12272-009-1418-4. Epub 2009 Apr 29.

PMID:
19407980
15.

Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages.

Yao Z, Zhang Q, Li X, Zhao D, Liu Y, Zhao K, Liu Y, Wang C, Jiang M, Li N, Cao X.

J Biol Chem. 2014 Mar 28;289(13):9372-9. doi: 10.1074/jbc.M113.533992. Epub 2014 Feb 18.

16.
17.

Nfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.

Zhao X, Ross EJ, Wang Y, Horwitz BH.

PLoS One. 2012;7(3):e32811. doi: 10.1371/journal.pone.0032811. Epub 2012 Mar 12.

18.

Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes.

Ku CS, Pham TX, Park Y, Kim B, Shin MS, Kang I, Lee J.

Biochim Biophys Acta. 2013 Apr;1830(4):2981-8. doi: 10.1016/j.bbagen.2013.01.018. Epub 2013 Jan 26.

19.

Gnotobiotic IL-10-/-;NF-kappa B(EGFP) mice reveal the critical role of TLR/NF-kappa B signaling in commensal bacteria-induced colitis.

Karrasch T, Kim JS, Muhlbauer M, Magness ST, Jobin C.

J Immunol. 2007 May 15;178(10):6522-32.

20.

A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs.

Cheng F, Lienlaf M, Wang HW, Perez-Villarroel P, Lee C, Woan K, Rock-Klotz J, Sahakian E, Woods D, Pinilla-Ibarz J, Kalin J, Tao J, Hancock W, Kozikowski A, Seto E, Villagra A, Sotomayor EM.

J Immunol. 2014 Sep 15;193(6):2850-62. doi: 10.4049/jimmunol.1302778. Epub 2014 Aug 8.

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