Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 110

Similar articles for PubMed (Select 22781549)

1.

Progranulin regulates neuronal outgrowth independent of sortilin.

Gass J, Lee WC, Cook C, Finch N, Stetler C, Jansen-West K, Lewis J, Link CD, Rademakers R, Nykjær A, Petrucelli L.

Mol Neurodegener. 2012 Jul 10;7:33. doi: 10.1186/1750-1326-7-33.

2.

The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding.

De Muynck L, Herdewyn S, Beel S, Scheveneels W, Van Den Bosch L, Robberecht W, Van Damme P.

Neurobiol Aging. 2013 Nov;34(11):2541-7. doi: 10.1016/j.neurobiolaging.2013.04.022. Epub 2013 May 24.

PMID:
23706646
3.

Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.

Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, Gao FB, Petrucelli L.

Hum Mol Genet. 2014 Mar 15;23(6):1467-78. doi: 10.1093/hmg/ddt534. Epub 2013 Oct 26.

4.

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM.

Neuron. 2010 Nov 18;68(4):654-67. doi: 10.1016/j.neuron.2010.09.034.

5.

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival.

Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, Carmeliet P, Van Den Bosch L, Robberecht W.

J Cell Biol. 2008 Apr 7;181(1):37-41. doi: 10.1083/jcb.200712039. Epub 2008 Mar 31.

6.

Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.

Chen X, Chang J, Deng Q, Xu J, Nguyen TA, Martens LH, Cenik B, Taylor G, Hudson KF, Chung J, Yu K, Yu P, Herz J, Farese RV Jr, Kukar T, Tansey MG.

J Neurosci. 2013 May 22;33(21):9202-13. doi: 10.1523/JNEUROSCI.5336-12.2013.

7.

Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.

Tanaka Y, Matsuwaki T, Yamanouchi K, Nishihara M.

Neuroscience. 2013 Oct 10;250:8-19. doi: 10.1016/j.neuroscience.2013.06.049. Epub 2013 Jul 2.

PMID:
23830905
8.

Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging.

Ahmed Z, Sheng H, Xu YF, Lin WL, Innes AE, Gass J, Yu X, Wuertzer CA, Hou H, Chiba S, Yamanouchi K, Leissring M, Petrucelli L, Nishihara M, Hutton ML, McGowan E, Dickson DW, Lewis J.

Am J Pathol. 2010 Jul;177(1):311-24. doi: 10.2353/ajpath.2010.090915. Epub 2010 Jun 3. Erratum in: Am J Pathol. 2010 Oct;177(4):2146. Wuertzer, Charles A [added].

9.

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.

Carrasquillo MM, Nicholson AM, Finch N, Gibbs JR, Baker M, Rutherford NJ, Hunter TA, DeJesus-Hernandez M, Bisceglio GD, Mackenzie IR, Singleton A, Cookson MR, Crook JE, Dillman A, Hernandez D, Petersen RC, Graff-Radford NR, Younkin SG, Rademakers R.

Am J Hum Genet. 2010 Dec 10;87(6):890-7. doi: 10.1016/j.ajhg.2010.11.002. Epub 2010 Nov 18.

10.

Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β.

Gao X, Joselin AP, Wang L, Kar A, Ray P, Bateman A, Goate AM, Wu JY.

Protein Cell. 2010 Jun;1(6):552-62. doi: 10.1007/s13238-010-0067-1. Epub 2010 Jul 7.

PMID:
21204008
11.

Pathogenic cysteine mutations affect progranulin function and production of mature granulins.

Wang J, Van Damme P, Cruchaga C, Gitcho MA, Vidal JM, Seijo-Martínez M, Wang L, Wu JY, Robberecht W, Goate A.

J Neurochem. 2010 Mar;112(5):1305-15. doi: 10.1111/j.1471-4159.2009.06546.x. Epub 2009 Dec 17.

12.

Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations.

Josephs KA, Ahmed Z, Katsuse O, Parisi JF, Boeve BF, Knopman DS, Petersen RC, Davies P, Duara R, Graff-Radford NR, Uitti RJ, Rademakers R, Adamson J, Baker M, Hutton ML, Dickson DW.

J Neuropathol Exp Neurol. 2007 Feb;66(2):142-51.

PMID:
17278999
13.

PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers.

Alquézar C, Esteras N, de la Encarnación A, Alzualde A, Moreno F, López de Munain A, Martín-Requero A.

Neurobiol Aging. 2014 Apr;35(4):886-98. doi: 10.1016/j.neurobiolaging.2013.09.021. Epub 2013 Oct 16.

PMID:
24139281
14.

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV Jr, Gan L.

Nat Med. 2014 Oct;20(10):1157-64. doi: 10.1038/nm.3672. Epub 2014 Sep 28.

15.

Serum progranulin levels in patients with frontotemporal lobar degeneration and Alzheimer's disease: detection of GRN mutations in a Spanish cohort.

Antonell A, Gil S, Sánchez-Valle R, Balasa M, Bosch B, Prat MC, Chiollaz AC, Fernández M, Yagüe J, Molinuevo JL, Lladó A.

J Alzheimers Dis. 2012;31(3):581-91. doi: 10.3233/JAD-2012-112120.

PMID:
22647257
16.

Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.

Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C.

J Neurosci. 2011 Feb 2;31(5):1885-94. doi: 10.1523/JNEUROSCI.5757-10.2011.

17.

Potential mechanisms of progranulin-deficient FTLD.

Ward ME, Miller BL.

J Mol Neurosci. 2011 Nov;45(3):574-82. doi: 10.1007/s12031-011-9622-3. Epub 2011 Sep 3. Review.

18.

Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.

Prudencio M, Jansen-West KR, Lee WC, Gendron TF, Zhang YJ, Xu YF, Gass J, Stuani C, Stetler C, Rademakers R, Dickson DW, Buratti E, Petrucelli L.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21510-5. doi: 10.1073/pnas.1211577110. Epub 2012 Dec 10.

19.

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.

Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV Jr.

J Clin Invest. 2012 Nov;122(11):3955-9. doi: 10.1172/JCI63113. Epub 2012 Oct 8.

20.

Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice.

Tanaka Y, Chambers JK, Matsuwaki T, Yamanouchi K, Nishihara M.

Acta Neuropathol Commun. 2014 Jul 15;2:78. doi: 10.1186/s40478-014-0078-x.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk