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Results: 1 to 20 of 106

Similar articles for PubMed (Select 22780198)

1.

O-Nucleoside, S-nucleoside, and N-nucleoside probes of lumazine synthase and riboflavin synthase.

Talukdar A, Zhao Y, Lv W, Bacher A, Illarionov B, Fischer M, Cushman M.

J Org Chem. 2012 Jul 20;77(14):6239-61. doi: 10.1021/jo3010364. Epub 2012 Jul 10.

2.

Synthesis and enzyme inhibitory activity of the s-nucleoside analogue of the ribitylaminopyrimidine substrate of lumazine synthase and product of riboflavin synthase.

Talukdar A, Illarionov B, Bacher A, Fischer M, Cushman M.

J Org Chem. 2007 Sep 14;72(19):7167-75. Epub 2007 Aug 16.

PMID:
17696548
4.

A new series of N-[2,4-dioxo-6-d-ribitylamino-1,2,3,4-tetrahydropyrimidin-5-yl]oxalamic acid derivatives as inhibitors of lumazine synthase and riboflavin synthase: design, synthesis, biochemical evaluation, crystallography, and mechanistic implications.

Zhang Y, Illarionov B, Morgunova E, Jin G, Bacher A, Fischer M, Ladenstein R, Cushman M.

J Org Chem. 2008 Apr 4;73(7):2715-24. doi: 10.1021/jo702631a. Epub 2008 Mar 11.

PMID:
18331058
6.
7.

Design, synthesis, and biochemical evaluation of 1,5,6,7-tetrahydro-6,7-dioxo-9-D-ribitylaminolumazines bearing alkyl phosphate substituents as inhibitors of lumazine synthase and riboflavin synthase.

Cushman M, Jin G, Sambaiah T, Illarionov B, Fischer M, Ladenstein R, Bacher A.

J Org Chem. 2005 Sep 30;70(20):8162-70. Erratum in: J Org Chem. 2005 Oct 28;70(22):9092. Sambaiah, Thota [added].

8.
9.

A new series of 3-alkyl phosphate derivatives of 4,5,6,7-tetrahydro-1-D-ribityl-1H-pyrazolo[3,4-d]pyrimidinedione as inhibitors of lumazine synthase: design, synthesis, and evaluation.

Zhang Y, Jin G, Illarionov B, Bacher A, Fischer M, Cushman M.

J Org Chem. 2007 Sep 14;72(19):7176-84. Epub 2007 Aug 18.

PMID:
17705537
10.
11.
12.
13.

Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.

Morgunova E, Meining W, Illarionov B, Haase I, Jin G, Bacher A, Cushman M, Fischer M, Ladenstein R.

Biochemistry. 2005 Mar 1;44(8):2746-58.

PMID:
15723519
14.

Evolution of vitamin B2 biosynthesis: 6,7-dimethyl-8-ribityllumazine synthases of Brucella.

Zylberman V, Klinke S, Haase I, Bacher A, Fischer M, Goldbaum FA.

J Bacteriol. 2006 Sep;188(17):6135-42.

15.

The lumazine synthase/riboflavin synthase complex: shapes and functions of a highly variable enzyme system.

Ladenstein R, Fischer M, Bacher A.

FEBS J. 2013 Jun;280(11):2537-63. doi: 10.1111/febs.12255. Epub 2013 Apr 24. Review.

PMID:
23551830
16.

A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.

Zhang X, Meining W, Cushman M, Haase I, Fischer M, Bacher A, Ladenstein R.

J Mol Biol. 2003 Apr 18;328(1):167-82.

PMID:
12684006
18.

Lumazine synthase from Candida albicans as an anti-fungal target enzyme: structural and biochemical basis for drug design.

Morgunova E, Saller S, Haase I, Cushman M, Bacher A, Fischer M, Ladenstein R.

J Biol Chem. 2007 Jun 8;282(23):17231-41. Epub 2007 Apr 18.

19.

Discovery and development of a small molecule library with lumazine synthase inhibitory activity.

Talukdar A, Breen M, Bacher A, Illarionov B, Fischer M, Georg G, Ye QZ, Cushman M.

J Org Chem. 2009 Aug 7;74(15):5123-34. doi: 10.1021/jo900238q.

20.

(Trifluoromethyl)lumazine derivatives as 19F NMR probes for lumazine protein.

Scheuring J, Lee J, Cushman M, Patel H, Patrick DA, Bacher A.

Biochemistry. 1994 Jun 21;33(24):7634-40.

PMID:
8011629
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