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Focal but reversible diastolic sheet dysfunction reflects regional calcium mishandling in dystrophic mdx mouse hearts.

Cheng YJ, Lang D, Caruthers SD, Efimov IR, Chen J, Wickline SA.

Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H559-68. doi: 10.1152/ajpheart.00321.2012. Epub 2012 Jul 9.


Intracellular calcium handling in ventricular myocytes from mdx mice.

Williams IA, Allen DG.

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H846-55. Epub 2006 Sep 29.


Early manifestation of alteration in cardiac function in dystrophin deficient mdx mouse using 3D CMR tagging.

Li W, Liu W, Zhong J, Yu X.

J Cardiovasc Magn Reson. 2009 Oct 22;11:40. doi: 10.1186/1532-429X-11-40.


Hypersensitivity of excitation-contraction coupling in dystrophic cardiomyocytes.

Ullrich ND, Fanchaouy M, Gusev K, Shirokova N, Niggli E.

Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H1992-2003. doi: 10.1152/ajpheart.00602.2009. Epub 2009 Sep 25.


Blunted cardiac beta-adrenergic response as an early indication of cardiac dysfunction in Duchenne muscular dystrophy.

Li Y, Zhang S, Zhang X, Li J, Ai X, Zhang L, Yu D, Ge S, Peng Y, Chen X.

Cardiovasc Res. 2014 Jul 1;103(1):60-71. doi: 10.1093/cvr/cvu119. Epub 2014 May 8.


Heterogeneous abnormalities of in-vivo left ventricular calcium influx and function in mouse models of muscular dystrophy cardiomyopathy.

Greally E, Davison BJ, Blain A, Laval S, Blamire A, Straub V, MacGowan GA.

J Cardiovasc Magn Reson. 2013 Jan 16;15:4. doi: 10.1186/1532-429X-15-4.


Abnormal cardiac morphology, function and energy metabolism in the dystrophic mdx mouse: an MRI and MRS study.

Zhang W, ten Hove M, Schneider JE, Stuckey DJ, Sebag-Montefiore L, Bia BL, Radda GK, Davies KE, Neubauer S, Clarke K.

J Mol Cell Cardiol. 2008 Dec;45(6):754-60. doi: 10.1016/j.yjmcc.2008.09.125. Epub 2008 Sep 27.


Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

Koenig X, Rubi L, Obermair GJ, Cervenka R, Dang XB, Lukacs P, Kummer S, Bittner RE, Kubista H, Todt H, Hilber K.

Am J Physiol Heart Circ Physiol. 2014 Feb 15;306(4):H564-73. doi: 10.1152/ajpheart.00441.2013. Epub 2013 Dec 13.


Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10.

Nitahara-Kasahara Y, Hayashita-Kinoh H, Chiyo T, Nishiyama A, Okada H, Takeda S, Okada T.

Hum Mol Genet. 2014 Aug 1;23(15):3990-4000. doi: 10.1093/hmg/ddu113. Epub 2014 Mar 21.


Early right ventricular fibrosis and reduction in biventricular cardiac reserve in the dystrophin-deficient mdx heart.

Meyers TA, Townsend D.

Am J Physiol Heart Circ Physiol. 2015 Feb 15;308(4):H303-15. doi: 10.1152/ajpheart.00485.2014. Epub 2014 Dec 5.


Low dystrophin levels in heart can delay heart failure in mdx mice.

van Putten M, van der Pijl EM, Hulsker M, Verhaart IE, Nadarajah VD, van der Weerd L, Aartsma-Rus A.

J Mol Cell Cardiol. 2014 Apr;69:17-23. doi: 10.1016/j.yjmcc.2014.01.009. Epub 2014 Jan 29.


L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte.

Viola HM, Davies SM, Filipovska A, Hool LC.

Am J Physiol Heart Circ Physiol. 2013 Mar 15;304(6):H767-75. doi: 10.1152/ajpheart.00700.2012. Epub 2013 Jan 18.


In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.

Stuckey DJ, Carr CA, Camelliti P, Tyler DJ, Davies KE, Clarke K.

PLoS One. 2012;7(1):e28569. doi: 10.1371/journal.pone.0028569. Epub 2012 Jan 3.


Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice.

Spurney CF, Guerron AD, Yu Q, Sali A, van der Meulen JH, Hoffman EP, Nagaraju K.

BMC Cardiovasc Disord. 2011 May 16;11:20. doi: 10.1186/1471-2261-11-20.


The heart in Duchenne muscular dystrophy: early detection of contractile performance alteration.

Wagner S, Knipp S, Weber C, Hein S, Schinkel S, Walther A, Bekeredjian R, Müller OJ, Friedrich O.

J Cell Mol Med. 2012 Dec;16(12):3028-36. doi: 10.1111/j.1582-4934.2012.01630.x.


Increased connective tissue growth factor associated with cardiac fibrosis in the mdx mouse model of dystrophic cardiomyopathy.

Au CG, Butler TL, Sherwood MC, Egan JR, North KN, Winlaw DS.

Int J Exp Pathol. 2011 Feb;92(1):57-65. doi: 10.1111/j.1365-2613.2010.00750.x. Epub 2010 Dec 1.


The role of reactive oxygen species in the hearts of dystrophin-deficient mdx mice.

Williams IA, Allen DG.

Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1969-77. Epub 2007 Jun 15.


Ryanodine receptor Ca2+ sensitivity and excitation-contraction coupling in muscular dystrophy and heart failure: similar and yet different.

Shannon TR.

Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H1965-6. doi: 10.1152/ajpheart.00945.2009. Epub 2009 Oct 16. No abstract available.


Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z.

Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2096-108. doi: 10.1152/ajpheart.00452.2009. Epub 2009 Oct 2.


Muscular dystrophy: from gene to patient.

Hopkins JC, Bia BL, Crilley JG, Boehm EA, Sang AE, Tinsley JM, King LM, Radda GK, Davies KE, Clarke K.

MAGMA. 2000 Nov;11(1-2):7-9. No abstract available.

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