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Items: 1 to 20 of 105

1.

Modeling perimenopause in Sprague-Dawley rats by chemical manipulation of the transition to ovarian failure.

Frye JB, Lukefahr AL, Wright LE, Marion SL, Hoyer PB, Funk JL.

Comp Med. 2012 Jun;62(3):193-202.

2.

Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats.

Reis FM, Pestana-Oliveira N, Leite CM, Lima FB, Brandão ML, Graeff FG, Del-Ben CM, Anselmo-Franci JA.

Psychoneuroendocrinology. 2014 Nov;49:130-40. doi: 10.1016/j.psyneuen.2014.06.019. Epub 2014 Jul 12.

PMID:
25080405
3.

Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes.

Muhammad FS, Goode AK, Kock ND, Arifin EA, Cline JM, Adams MR, Hoyer PB, Christian PJ, Isom S, Kaplan JR, Appt SE.

Comp Med. 2009 Feb;59(1):46-59.

4.

Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause.

Lohff JC, Christian PJ, Marion SL, Arrandale A, Hoyer PB.

Comp Med. 2005 Dec;55(6):523-7.

PMID:
16422148
5.

The follicle-deplete mouse ovary produces androgen.

Mayer LP, Devine PJ, Dyer CA, Hoyer PB.

Biol Reprod. 2004 Jul;71(1):130-8. Epub 2004 Mar 3.

6.

Decreased bone mineral density in rats rendered follicle-deplete by an ovotoxic chemical correlates with changes in follicle-stimulating hormone and inhibin A.

Lukefahr AL, Frye JB, Wright LE, Marion SL, Hoyer PB, Funk JL.

Calcif Tissue Int. 2012 Mar;90(3):239-49. doi: 10.1007/s00223-011-9565-2. Epub 2012 Jan 17.

7.

Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause.

Lohff JC, Christian PJ, Marion SL, Hoyer PB.

Menopause. 2006 May-Jun;13(3):482-8.

PMID:
16735946
8.

Accelerated follicle depletion in vitro and in vivo in Sprague-Dawley rats using the combination of 4-vinylcyclohexene diepoxide and triptolide.

Dyer CA, Raymond-Whish S, Schmuki S, Fisher T, Pyzyna B, Bennett A, Mayer LP.

J Zoo Wildl Med. 2013 Dec;44(4 Suppl):S9-17.

PMID:
24437079
9.
10.

Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis).

Appt SE, Clarkson TB, Hoyer PB, Kock ND, Goode AK, May MC, Persyn JT, Vail NK, Ethun KF, Chen H, Sen N, Kaplan JR.

Comp Med. 2010 Oct;60(5):380-8.

11.

ANG II-induced hypertension in the VCD mouse model of menopause is prevented by estrogen replacement during perimenopause.

Pollow DP Jr, Romero-Aleshire MJ, Sanchez JN, Konhilas JP, Brooks HL.

Am J Physiol Regul Integr Comp Physiol. 2015 Dec 15;309(12):R1546-52. doi: 10.1152/ajpregu.00170.2015. Epub 2015 Oct 21.

PMID:
26491098
12.

4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats.

Wright LE, Frye JB, Lukefahr AL, Marion SL, Hoyer PB, Besselsen DG, Funk JL.

Reprod Toxicol. 2011 Jul;32(1):26-32. doi: 10.1016/j.reprotox.2011.05.005. Epub 2011 May 20.

13.

Conditions and possible mechanisms of VCD-induced ovarian failure.

Liu W, Wang LY, Xing XX, Fan GW.

Altern Lab Anim. 2015 Dec;43(6):385-92.

PMID:
26753941
14.

Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide.

Devine PJ, Sipes IG, Skinner MK, Hoyer PB.

Toxicol Appl Pharmacol. 2002 Oct 15;184(2):107-15.

PMID:
12408955
15.

Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice.

Rivera Z, Christian PJ, Marion SL, Brooks HL, Hoyer PB.

Biol Reprod. 2009 Feb;80(2):328-36. doi: 10.1095/biolreprod.108.070359. Epub 2008 Oct 1.

16.

Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause.

Mayer LP, Dyer CA, Eastgard RL, Hoyer PB, Banka CL.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1910-6. Epub 2005 Jun 30.

19.

Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.

Springer LN, McAsey ME, Flaws JA, Tilly JL, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 1996 Aug;139(2):394-401.

PMID:
8806857
20.

17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats.

Thompson KE, Sipes IG, Greenstein BD, Hoyer PB.

Endocrinology. 2002 Mar;143(3):1058-65.

PMID:
11861533
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