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Items: 1 to 20 of 138

1.

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

Nabel CS, Jia H, Ye Y, Shen L, Goldschmidt HL, Stivers JT, Zhang Y, Kohli RM.

Nat Chem Biol. 2012 Sep;8(9):751-8. doi: 10.1038/nchembio.1042. Epub 2012 Jul 8.

2.

[Oxidation and deamination of nucleobases as an epigenetic tool].

Guz J, Jurgowiak M, Oliński R.

Postepy Hig Med Dosw (Online). 2012 May 24;66:275-86. Review. Polish.

3.

Nucleic acid determinants for selective deamination of DNA over RNA by activation-induced deaminase.

Nabel CS, Lee JW, Wang LC, Kohli RM.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14225-30. doi: 10.1073/pnas.1306345110. Epub 2013 Aug 13.

4.

DNA deamination in immunity: AID in the context of its APOBEC relatives.

Conticello SG, Langlois MA, Yang Z, Neuberger MS.

Adv Immunol. 2007;94:37-73. Review.

PMID:
17560271
5.

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.

Wijesinghe P, Bhagwat AS.

Nucleic Acids Res. 2012 Oct;40(18):9206-17. doi: 10.1093/nar/gks685. Epub 2012 Jul 13.

6.

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.

Guo JU, Su Y, Zhong C, Ming GL, Song H.

Cell. 2011 Apr 29;145(3):423-34. doi: 10.1016/j.cell.2011.03.022. Epub 2011 Apr 14.

7.

In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1).

Petersen-Mahrt SK, Neuberger MS.

J Biol Chem. 2003 May 30;278(22):19583-6. Epub 2003 Apr 14.

8.

Epigenetic reprogramming: is deamination key to active DNA demethylation?

Teperek-Tkacz M, Pasque V, Gentsch G, Ferguson-Smith AC.

Reproduction. 2011 Nov;142(5):621-32. doi: 10.1530/REP-11-0148. Epub 2011 Sep 12. Review.

9.

The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.

Nabel CS, Manning SA, Kohli RM.

ACS Chem Biol. 2012 Jan 20;7(1):20-30. doi: 10.1021/cb2002895. Epub 2011 Oct 31. Review.

10.

AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.

Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, Visnes T, Aas PA, Liabakk NB, Slupphaug G, Sætrom P, Kavli B, Krokan HE.

DNA Repair (Amst). 2015 Jan;25:60-71. doi: 10.1016/j.dnarep.2014.11.006. Epub 2014 Nov 24.

11.

Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.

Beale RC, Petersen-Mahrt SK, Watt IN, Harris RS, Rada C, Neuberger MS.

J Mol Biol. 2004 Mar 26;337(3):585-96.

PMID:
15019779
12.

AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud.

Rangam G, Schmitz KM, Cobb AJ, Petersen-Mahrt SK.

PLoS One. 2012;7(8):e43279. doi: 10.1371/journal.pone.0043279. Epub 2012 Aug 20.

13.

Photochemical deamination and demethylation of 5-methylcytosine.

Privat E, Sowers LC.

Chem Res Toxicol. 1996 Jun;9(4):745-50.

PMID:
8831819
14.

Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase.

van der Wijst MG, Venkiteswaran M, Chen H, Xu GL, Plösch T, Rots MG.

Epigenetics. 2015;10(8):671-6. doi: 10.1080/15592294.2015.1062204. Review.

15.

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.

Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK.

J Biol Chem. 2004 Dec 10;279(50):52353-60. Epub 2004 Sep 24.

16.

The APOBEC-2 crystal structure and functional implications for the deaminase AID.

Prochnow C, Bransteitter R, Klein MG, Goodman MF, Chen XS.

Nature. 2007 Jan 25;445(7126):447-51. Epub 2006 Dec 24.

PMID:
17187054
17.

A high-throughput assay for DNA deaminases.

Wang M, Rada C, Neuberger MS.

Methods Mol Biol. 2011;718:171-84. doi: 10.1007/978-1-61779-018-8_11.

PMID:
21370049
18.

DNA demethylation dynamics.

Bhutani N, Burns DM, Blau HM.

Cell. 2011 Sep 16;146(6):866-72. doi: 10.1016/j.cell.2011.08.042.

19.

Reward versus risk: DNA cytidine deaminases triggering immunity and disease.

Pham P, Bransteitter R, Goodman MF.

Biochemistry. 2005 Mar 1;44(8):2703-15. Review.

PMID:
15723516
20.

APOBEC-mediated editing of viral RNA.

Bishop KN, Holmes RK, Sheehy AM, Malim MH.

Science. 2004 Jul 30;305(5684):645.

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