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Items: 1 to 20 of 140

1.

Pancreas-enriched miRNA refines endocrine cell differentiation.

Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E.

Development. 2012 Aug;139(16):3021-31. doi: 10.1242/dev.080127. Epub 2012 Jul 4.

2.

The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas.

Hart AW, Mella S, Mendrychowski J, van Heyningen V, Kleinjan DA.

PLoS One. 2013;8(1):e54173. doi: 10.1371/journal.pone.0054173. Epub 2013 Jan 11.

3.

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.

Zhang X, Rowan S, Yue Y, Heaney S, Pan Y, Brendolan A, Selleri L, Maas RL.

Dev Biol. 2006 Dec 15;300(2):748-57. Epub 2006 Jun 27.

4.

Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells.

Wei R, Yang J, Liu GQ, Gao MJ, Hou WF, Zhang L, Gao HW, Liu Y, Chen GA, Hong TP.

Gene. 2013 Apr 15;518(2):246-55. doi: 10.1016/j.gene.2013.01.038. Epub 2013 Jan 29.

PMID:
23370336
5.

Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas.

St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A, Gruss P.

Nature. 1997 May 22;387(6631):406-9.

PMID:
9163426
6.

MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas.

Correa-Medina M, Bravo-Egana V, Rosero S, Ricordi C, Edlund H, Diez J, Pastori RL.

Gene Expr Patterns. 2009 Apr;9(4):193-9. doi: 10.1016/j.gep.2008.12.003. Epub 2008 Dec 24.

PMID:
19135553
7.

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.

Mellitzer G, Bonné S, Luco RF, Van De Casteele M, Lenne-Samuel N, Collombat P, Mansouri A, Lee J, Lan M, Pipeleers D, Nielsen FC, Ferrer J, Gradwohl G, Heimberg H.

EMBO J. 2006 Mar 22;25(6):1344-52. Epub 2006 Mar 2.

8.

Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function.

Gosmain Y, Marthinet E, Cheyssac C, Guérardel A, Mamin A, Katz LS, Bouzakri K, Philippe J.

J Biol Chem. 2010 Oct 22;285(43):33381-93. doi: 10.1074/jbc.M110.147215. Epub 2010 Jun 30.

9.

Brief report: miR-290-295 regulate embryonic stem cell differentiation propensities by repressing Pax6.

Kaspi H, Chapnik E, Levy M, Beck G, Hornstein E, Soen Y.

Stem Cells. 2013 Oct;31(10):2266-72. doi: 10.1002/stem.1465.

10.

Pax6 regulates gene expression in the vertebrate lens through miR-204.

Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R.

PLoS Genet. 2013;9(3):e1003357. doi: 10.1371/journal.pgen.1003357. Epub 2013 Mar 14.

11.

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.

Klimova L, Kozmik Z.

Development. 2014 Mar;141(6):1292-302. doi: 10.1242/dev.098822. Epub 2014 Feb 12.

12.

Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion.

Gosmain Y, Katz LS, Masson MH, Cheyssac C, Poisson C, Philippe J.

Mol Endocrinol. 2012 Apr;26(4):696-709. doi: 10.1210/me.2011-1256. Epub 2012 Mar 8.

PMID:
22403172
13.

Genetic determinants of pancreatic epsilon-cell development.

Heller RS, Jenny M, Collombat P, Mansouri A, Tomasetto C, Madsen OD, Mellitzer G, Gradwohl G, Serup P.

Dev Biol. 2005 Oct 1;286(1):217-24.

14.

A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye.

Elso C, Lu X, Weisner PA, Thompson HL, Skinner A, Carver E, Stubbs L.

Genesis. 2013 Sep;51(9):630-46. doi: 10.1002/dvg.22409. Epub 2013 Jul 23.

PMID:
23798316
15.

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.

Bhinge A, Poschmann J, Namboori SC, Tian X, Jia Hui Loh S, Traczyk A, Prabhakar S, Stanton LW.

EMBO J. 2014 Jun 2;33(11):1271-83. doi: 10.1002/embj.201387215. Epub 2014 May 6.

16.

Er81 is a downstream target of Pax6 in cortical progenitors.

Tuoc TC, Stoykova A.

BMC Dev Biol. 2008 Feb 28;8:23. doi: 10.1186/1471-213X-8-23.

17.

Expression of islet-specific microRNAs during human pancreatic development.

Joglekar MV, Joglekar VM, Hardikar AA.

Gene Expr Patterns. 2009 Feb;9(2):109-13. doi: 10.1016/j.gep.2008.10.001. Epub 2008 Oct 17.

PMID:
18977315
18.

Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation.

Davis J, Piatigorsky J.

Invest Ophthalmol Vis Sci. 2011 Jun 13;52(7):4158-68. doi: 10.1167/iovs.10-6726.

19.

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion.

Gosmain Y, Cheyssac C, Heddad Masson M, Dibner C, Philippe J.

Diabetes Obes Metab. 2011 Oct;13 Suppl 1:31-8. doi: 10.1111/j.1463-1326.2011.01445.x. Review.

PMID:
21824254
20.

Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish.

Lesaffre B, Joliot A, Prochiantz A, Volovitch M.

Neural Dev. 2007 Jan 17;2:2.

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