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Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself.

Dorjgochoo T, Gao YT, Chow WH, Shu XO, Yang G, Cai Q, Rothman N, Cai H, Li H, Deng X, Franke A, Roberts LJ, Milne G, Zheng W, Dai Q.

Am J Clin Nutr. 2012 Aug;96(2):405-14. doi: 10.3945/ajcn.112.034918. Epub 2012 Jul 3.


Obesity, age, and oxidative stress in middle-aged and older women.

Dorjgochoo T, Gao YT, Chow WH, Shu XO, Yang G, Cai Q, Rothman N, Cai H, Li H, Deng X, Shrubsole MJ, Murff H, Milne G, Zheng W, Dai Q.

Antioxid Redox Signal. 2011 Jun 15;14(12):2453-60. doi: 10.1089/ars.2010.3337. Epub 2011 Mar 21.


Intra-person variation of urinary biomarkers of oxidative stress and inflammation.

Wu X, Cai H, Xiang YB, Cai Q, Yang G, Liu D, Sanchez S, Zheng W, Milne G, Shu XO.

Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):947-52. doi: 10.1158/1055-9965.EPI-10-0046. Epub 2010 Mar 23.


2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite.

Hou X, Roberts LJ 2nd, Taber DF, Morrow JD, Kanai K, Gobeil F Jr, Beauchamp MH, Bernier SG, Lepage G, Varma DR, Chemtob S.

Am J Physiol Regul Integr Comp Physiol. 2001 Aug;281(2):R391-400.


Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study.

Dai Q, Gao YT, Shu XO, Yang G, Milne G, Cai Q, Wen W, Rothman N, Cai H, Li H, Xiang Y, Chow WH, Zheng W.

J Clin Oncol. 2009 May 20;27(15):2482-8. doi: 10.1200/JCO.2008.19.7970. Epub 2009 Apr 20.


Association of selenium, tocopherols, carotenoids, retinol, and 15-isoprostane F(2t) in serum or urine with prostate cancer risk: the multiethnic cohort.

Gill JK, Franke AA, Steven Morris J, Cooney RV, Wilkens LR, Le Marchand L, Goodman MT, Henderson BE, Kolonel LN.

Cancer Causes Control. 2009 Sep;20(7):1161-71. doi: 10.1007/s10552-009-9304-4. Epub 2009 Feb 11.


Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology.

Taylor AW, Bruno RS, Traber MG.

Lipids. 2008 Oct;43(10):925-36. doi: 10.1007/s11745-008-3222-1. Epub 2008 Aug 27.


Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha).

Dworski R, Roberts LJ 2nd, Murray JJ, Morrow JD, Hartert TV, Sheller JR.

Clin Exp Allergy. 2001 Mar;31(3):387-90.


Response of rat thoracic aorta to F(2)-isoprostane metabolites.

Cracowski JL, Camus L, Durand T, Devillier P, Guy A, Hardy G, Stanke-Labesque F, Rossi JC, Bessard G.

J Cardiovasc Pharmacol. 2002 Mar;39(3):396-403.


Increased urinary F2-isoprostanes in systemic sclerosis, but not in primary Raynaud's phenomenon: effect of cold exposure.

Cracowski JL, Carpentier PH, Imbert B, Cachot S, Stanke-Labesque F, Bessard J, Bessard G.

Arthritis Rheum. 2002 May;46(5):1319-23.


Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents.

Holt EM, Steffen LM, Moran A, Basu S, Steinberger J, Ross JA, Hong CP, Sinaiko AR.

J Am Diet Assoc. 2009 Mar;109(3):414-21. doi: 10.1016/j.jada.2008.11.036.


Isoprostane as a marker of oxidative stress in chronic heroin users: correlation with duration of heroin use or concomitant hepatitis C infection.

Kovatsi L, Njau S, Nikolaou K, Tsolakidou A, Karamouzis I, Thisiadou K.

Am J Drug Alcohol Abuse. 2010 Jan;36(1):13-7. doi: 10.3109/00952990903544794.


Urinary biomarkers of oxidative stress and breast cancer survival.

Nechuta S, Cai Q, Zheng Y, Milne GL, Cai H, Dai Q, Yang G, Zheng W, Lu W, Shu XO.

Cancer Causes Control. 2014 Jun;25(6):701-7. doi: 10.1007/s10552-014-0373-7. Epub 2014 Mar 29.


Contractile effects of 15-E2t-isoprostane and 15-F2t-isoprostane on chicken embryo ductus arteriosus.

van der Sterren S, Villamor E.

Comp Biochem Physiol A Mol Integr Physiol. 2011 Aug;159(4):436-44. doi: 10.1016/j.cbpa.2011.04.010. Epub 2011 May 3.


F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome.

De Felice C, Signorini C, Durand T, Oger C, Guy A, Bultel-Poncé V, Galano JM, Ciccoli L, Leoncini S, D'Esposito M, Filosa S, Pecorelli A, Valacchi G, Hayek J.

J Lipid Res. 2011 Dec;52(12):2287-97. doi: 10.1194/jlr.P017798. Epub 2011 Sep 13.


Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk.

Rossner P Jr, Gammon MD, Terry MB, Agrawal M, Zhang FF, Teitelbaum SL, Eng SM, Gaudet MM, Neugut AI, Santella RM.

Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):639-44.


Measurement of urinary F(2)-isoprostanes by gas chromatography-mass spectrometry is confounded by interfering substances.

Mas E, Barden A, Durand T, Galano JM, Croft KD, Mori TA.

Free Radic Res. 2010 Feb;44(2):191-8. doi: 10.3109/10715760903390838.


Quantification of dinor, dihydro metabolites of F2-isoprostanes in urine by liquid chromatography/tandem mass spectrometry.

Davies SS, Zackert W, Luo Y, Cunningham CC, Frisard M, Roberts LJ 2nd.

Anal Biochem. 2006 Jan 15;348(2):185-91. Epub 2005 Oct 26.


Changes in urinary dinor dihydro F(2)-isoprostane metabolite concentrations, a marker of oxidative stress, during and following asthma exacerbations.

Wu P, Roberts LJ 2nd, Shintani AK, Sheller JR, Minton PA, Higgins SB, Hartert TV.

Free Radic Res. 2007 Sep;41(9):956-62.

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