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Items: 1 to 20 of 100

1.

p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis.

Qian X, Hulit J, Suyama K, Eugenin EA, Belbin TJ, Loudig O, Smirnova T, Zhou ZN, Segall J, Locker J, Phillips GR, Norton L, Hazan RB.

Oncogene. 2013 May 2;32(18):2292-303, 2303.e1-7. doi: 10.1038/onc.2012.249. Epub 2012 Jul 2.

2.

A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion.

Dai M, Al-Odaini AA, Arakelian A, Rabbani SA, Ali S, Lebrun JJ.

Breast Cancer Res. 2012 Sep 20;14(5):R127. doi: 10.1186/bcr3322.

3.

Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor.

Wang X, Lin C, Zhao X, Liu A, Zhu J, Li X, Song L.

Mol Cancer. 2014 May 8;13:106. doi: 10.1186/1476-4598-13-106.

4.

Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.

Wang Z, Lee HJ, Chai Y, Hu H, Wang L, Zhang Y, Jiang C, Lü J.

Curr Cancer Drug Targets. 2010 May;10(3):307-18.

PMID:
20370687
5.

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest.

Sheahan S, Bellamy CO, Dunbar DR, Harrison DJ, Prost S.

BMC Cancer. 2007 Nov 19;7:215.

6.

IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.

Zuo S, Liu C, Wang J, Wang F, Xu W, Cui S, Yuan L, Chen X, Fan W, Cui M, Song G.

J Cancer Res Clin Oncol. 2012 Jun;138(6):1045-55. doi: 10.1007/s00432-012-1153-y. Epub 2012 Mar 6.

PMID:
22392074
7.

Stat6 cooperates with Sp1 in controlling breast cancer cell proliferation by modulating the expression of p21(Cip1/WAF1) and p27 (Kip1).

Wei M, Liu B, Gu Q, Su L, Yu Y, Zhu Z.

Cell Oncol (Dordr). 2013 Feb;36(1):79-93. doi: 10.1007/s13402-012-0115-3. Epub 2012 Nov 27.

PMID:
23184467
8.

Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors.

Roussos ET, Wang Y, Wyckoff JB, Sellers RS, Wang W, Li J, Pollard JW, Gertler FB, Condeelis JS.

Breast Cancer Res. 2010;12(6):R101. doi: 10.1186/bcr2784. Epub 2010 Nov 25.

9.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

10.

FHL2 regulates cell cycle-dependent and doxorubicin-induced p21Cip1/Waf1 expression in breast cancer cells.

Martin BT, Kleiber K, Wixler V, Raab M, Zimmer B, Kaufmann M, Strebhardt K.

Cell Cycle. 2007 Jul 15;6(14):1779-88.

PMID:
17682292
11.

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M.

Mol Cell Biol. 1997 Sep;17(9):5598-611.

12.

Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis, and chemoresistance.

Medina-Ramirez CM, Goswami S, Smirnova T, Bamira D, Benson B, Ferrick N, Segall J, Pollard JW, Kitsis RN.

Cancer Res. 2011 Dec 15;71(24):7705-15. doi: 10.1158/0008-5472.CAN-11-2192. Epub 2011 Oct 28.

13.

Evodiamine induces apoptosis and inhibits metastasis in MDA‑MB-231 human breast cancer cells in vitro and in vivo.

Du J, Wang XF, Zhou QM, Zhang TL, Lu YY, Zhang H, Su SB.

Oncol Rep. 2013 Aug;30(2):685-94. doi: 10.3892/or.2013.2498. Epub 2013 May 27.

PMID:
23708383
14.

Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest.

Järviluoma A, Child ES, Sarek G, Sirimongkolkasem P, Peters G, Ojala PM, Mann DJ.

Mol Cell Biol. 2006 Mar;26(6):2430-40.

16.

Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties.

Bearss DJ, Lee RJ, Troyer DA, Pestell RG, Windle JJ.

Cancer Res. 2002 Apr 1;62(7):2077-84.

17.

Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.

Wei Z, Jiang X, Liu F, Qiao H, Zhou B, Zhai B, Zhang L, Zhang X, Han L, Jiang H, Krissansen GW, Sun X.

Tumour Biol. 2013 Feb;34(1):181-92. doi: 10.1007/s13277-012-0527-8. Epub 2012 Dec 11.

PMID:
23229098
18.

Amniotic membrane-derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest.

Magatti M, De Munari S, Vertua E, Parolini O.

J Cell Mol Med. 2012 Sep;16(9):2208-18. doi: 10.1111/j.1582-4934.2012.01531.x.

19.

Integrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone.

Wei M, He Q, Yang Z, Wang Z, Zhang Q, Liu B, Gu Q, Su L, Yu Y, Zhu Z, Zhang G.

BMC Cancer. 2014 Jan 8;14:10. doi: 10.1186/1471-2407-14-10.

20.

Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumors.

Wakefield A, Soukupova J, Montagne A, Ranger J, French R, Muller WJ, Clarkson RW.

Cancer Res. 2013 Jan 15;73(2):745-55. doi: 10.1158/0008-5472.CAN-12-1321. Epub 2012 Nov 13.

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