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StearoylCoA desaturase-5: a novel regulator of neuronal cell proliferation and differentiation.

Sinner DI, Kim GJ, Henderson GC, Igal RA.

PLoS One. 2012;7(6):e39787. doi: 10.1371/journal.pone.0039787. Epub 2012 Jun 22.


FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth.

Du X, Wang QR, Chan E, Merchant M, Liu J, French D, Ashkenazi A, Qing J.

Cancer Res. 2012 Nov 15;72(22):5843-55. doi: 10.1158/0008-5472.CAN-12-1329. Epub 2012 Sep 26.


Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy.

Roongta UV, Pabalan JG, Wang X, Ryseck RP, Fargnoli J, Henley BJ, Yang WP, Zhu J, Madireddi MT, Lawrence RM, Wong TW, Rupnow BA.

Mol Cancer Res. 2011 Nov;9(11):1551-61. doi: 10.1158/1541-7786.MCR-11-0126. Epub 2011 Sep 27.


Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells.

Hess D, Chisholm JW, Igal RA.

PLoS One. 2010 Jun 30;5(6):e11394. doi: 10.1371/journal.pone.0011394.


Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK.

Scaglia N, Chisholm JW, Igal RA.

PLoS One. 2009 Aug 27;4(8):e6812. doi: 10.1371/journal.pone.0006812.


The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates.

Castro LF, Wilson JM, Gonçalves O, Galante-Oliveira S, Rocha E, Cunha I.

BMC Evol Biol. 2011 May 19;11:132. doi: 10.1186/1471-2148-11-132.


Polymorphisms in genes in the SREBP1 signalling pathway and SCD are associated with milk fatty acid composition in Holstein cattle.

Rincon G, Islas-Trejo A, Castillo AR, Bauman DE, German BJ, Medrano JF.

J Dairy Res. 2012 Feb;79(1):66-75. doi: 10.1017/S002202991100080X. Epub 2011 Nov 25.


Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells.

Minville-Walz M, Pierre AS, Pichon L, Bellenger S, Fèvre C, Bellenger J, Tessier C, Narce M, Rialland M.

PLoS One. 2010 Dec 16;5(12):e14363. doi: 10.1371/journal.pone.0014363.


Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice.

Fritz V, Benfodda Z, Rodier G, Henriquet C, Iborra F, Avancès C, Allory Y, de la Taille A, Culine S, Blancou H, Cristol JP, Michel F, Sardet C, Fajas L.

Mol Cancer Ther. 2010 Jun;9(6):1740-54. doi: 10.1158/1535-7163.MCT-09-1064. Epub 2010 Jun 8.


SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice.

Li L, Wang C, Calvisi DF, Evert M, Pilo MG, Jiang L, Yuneva M, Chen X.

PLoS One. 2013 Sep 19;8(9):e75104. doi: 10.1371/journal.pone.0075104. eCollection 2013.


Decreasing stearoyl-CoA desaturase-1 expression inhibits β-catenin signaling in breast cancer cells.

Mauvoisin D, Charfi C, Lounis AM, Rassart E, Mounier C.

Cancer Sci. 2013 Jan;104(1):36-42. doi: 10.1111/cas.12032. Epub 2012 Nov 9.


Regulation of stearoyl-CoA desaturase genes: role in cellular metabolism and preadipocyte differentiation.

Kim YC, Ntambi JM.

Biochem Biophys Res Commun. 1999 Dec 9;266(1):1-4. Review.


The evolutionary pattern and the regulation of stearoyl-CoA desaturase genes.

Wu X, Zou X, Chang Q, Zhang Y, Li Y, Zhang L, Huang J, Liang B.

Biomed Res Int. 2013;2013:856521. doi: 10.1155/2013/856521. Epub 2013 Nov 7.


Stearoyl-CoA desaturase--a new player in skeletal muscle metabolism regulation.

Dobrzyń A, Dobrzyń P.

J Physiol Pharmacol. 2006 Nov;57 Suppl 10:31-42. Review.


Regulation of stearoyl-CoA desaturases and role in metabolism.

Ntambi JM, Miyazaki M.

Prog Lipid Res. 2004 Mar;43(2):91-104. Review.


Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes.

Matsui H, Yokoyama T, Sekiguchi K, Iijima D, Sunaga H, Maniwa M, Ueno M, Iso T, Arai M, Kurabayashi M.

PLoS One. 2012;7(3):e33283. doi: 10.1371/journal.pone.0033283. Epub 2012 Mar 8.


Recent insights into stearoyl-CoA desaturase-1.

Ntambi JM, Miyazaki M.

Curr Opin Lipidol. 2003 Jun;14(3):255-61. Review.

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