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Results: 1 to 20 of 92

1.

Targeting eNOS in pancreatic cancer.

Lampson BL, Kendall SD, Ancrile BB, Morrison MM, Shealy MJ, Barrientos KS, Crowe MS, Kashatus DF, White RR, Gurley SB, Cardona DM, Counter CM.

Cancer Res. 2012 Sep 1;72(17):4472-82. doi: 10.1158/0008-5472.CAN-12-0057. Epub 2012 Jun 27.

PMID:
22738914
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.

Sureban SM, May R, Weygant N, Qu D, Chandrakesan P, Bannerman-Menson E, Ali N, Pantazis P, Westphalen CB, Wang TC, Houchen CW.

Cancer Lett. 2014 Aug 28;351(1):151-61. doi: 10.1016/j.canlet.2014.05.011. Epub 2014 May 28.

PMID:
24880079
[PubMed - indexed for MEDLINE]
3.
4.

Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2.

Ohtsu N, Takaoka K, Segawa E, Hashitani S, Noguchi K, Kishimoto H, Urade M.

Oncol Rep. 2010 Jul;24(1):31-6.

PMID:
20514441
[PubMed - indexed for MEDLINE]
5.

Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model.

Siddique HR, Liao DJ, Mishra SK, Schuster T, Wang L, Matter B, Campbell PM, Villalta P, Nanda S, Deng Y, Saleem M.

Int J Cancer. 2012 Oct 1;131(7):1720-31. doi: 10.1002/ijc.27409. Epub 2012 Feb 18.

PMID:
22190076
[PubMed - indexed for MEDLINE]
6.

[Effect of nitric oxide derived from endothelial nitric oxide synthase on tumor angiogenesis].

Mei K, Cai XH, Du L, Chen YF, Huang S, Chen J, Yin XD, Zhang ZX, Zhao X, Zhou CY, Yu JR.

Chin J Cancer. 2010 Jan;29(1):32-7. Chinese.

PMID:
20038308
[PubMed - indexed for MEDLINE]
Free Article
7.

Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthase-deficient mice.

Suda O, Tsutsui M, Morishita T, Tanimoto A, Horiuchi M, Tasaki H, Huang PL, Sasaguri Y, Yanagihara N, Nakashima Y.

Circulation. 2002 Sep 24;106(13):1729-35.

PMID:
12270870
[PubMed - indexed for MEDLINE]
Free Article
8.

Synergistic effect between erlotinib and MEK inhibitors in KRAS wild-type human pancreatic cancer cells.

Diep CH, Munoz RM, Choudhary A, Von Hoff DD, Han H.

Clin Cancer Res. 2011 May 1;17(9):2744-56. doi: 10.1158/1078-0432.CCR-10-2214. Epub 2011 Mar 8.

PMID:
21385921
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The estrogen effects on endothelial repair and mitogen-activated protein kinase activation are abolished in endothelial nitric-oxide (NO) synthase knockout mice, but not by NO synthase inhibition by N-nitro-L-arginine methyl ester.

Billon A, Lehoux S, Lam Shang Leen L, Laurell H, Filipe C, Benouaich V, Brouchet L, Dessy C, Gourdy P, Gadeau AP, Tedgui A, Balligand JL, Arnal JF.

Am J Pathol. 2008 Mar;172(3):830-8. doi: 10.2353/ajpath.2008.070439. Epub 2008 Feb 14.

PMID:
18276789
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma.

Avan A, Caretti V, Funel N, Galvani E, Maftouh M, Honeywell RJ, Lagerweij T, Van Tellingen O, Campani D, Fuchs D, Verheul HM, Schuurhuis GJ, Boggi U, Peters GJ, Würdinger T, Giovannetti E.

Cancer Res. 2013 Nov 15;73(22):6745-56. doi: 10.1158/0008-5472.CAN-13-0837. Epub 2013 Oct 1.

PMID:
24085787
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

In vitro effects of nitric oxide synthase inhibitor L-NAME on oral squamous cell carcinoma: a preliminary study.

Shang ZJ, Li ZB, Li JR.

Int J Oral Maxillofac Surg. 2006 Jun;35(6):539-43. Epub 2006 Feb 23.

PMID:
16497478
[PubMed - indexed for MEDLINE]
13.

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.

Aichler M, Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I.

J Pathol. 2012 Apr;226(5):723-34. doi: 10.1002/path.3017. Epub 2012 Jan 17.

PMID:
21984419
[PubMed - indexed for MEDLINE]
14.

K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.

Wei F, Liu Y, Bellail AC, Olson JJ, Sun SY, Lu G, Ding L, Yuan C, Wang G, Hao C.

Cancer Lett. 2012 Sep 1;322(1):58-69. doi: 10.1016/j.canlet.2012.02.005. Epub 2012 Feb 14.

PMID:
22342683
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pancreatic tumor sensitivity to plasma L-asparagine starvation.

Dufour E, Gay F, Aguera K, Scoazec JY, Horand F, Lorenzi PL, Godfrin Y.

Pancreas. 2012 Aug;41(6):940-8. doi: 10.1097/MPA.0b013e318247d903.

PMID:
22513289
[PubMed - indexed for MEDLINE]
16.

Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis.

Lin SZ, Wei WT, Chen H, Chen KJ, Tong HF, Wang ZH, Ni ZL, Liu HB, Guo HC, Liu DL.

PLoS One. 2012;7(8):e42146. doi: 10.1371/journal.pone.0042146. Epub 2012 Aug 2.

PMID:
22876305
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The KRAS-PDEδ interaction is a therapeutic target.

[No authors listed]

Cancer Discov. 2013 Jul;3(7):OF20. doi: 10.1158/2159-8290.CD-RW2013-116. Epub 2013 May 30.

PMID:
23847364
[PubMed - indexed for MEDLINE]
18.

Endothelial nitric oxide synthase affects both early and late collateral arterial adaptation and blood flow recovery after induction of hind limb ischemia in mice.

Park B, Hoffman A, Yang Y, Yan J, Tie G, Bagshahi H, Nowicki PT, Messina LM.

J Vasc Surg. 2010 Jan;51(1):165-73. doi: 10.1016/j.jvs.2009.08.045. Epub 2009 Oct 30.

PMID:
19879098
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase.

Morais C, Ebrahem Q, Anand-Apte B, Parat MO.

Am J Pathol. 2012 Apr;180(4):1702-14. doi: 10.1016/j.ajpath.2011.12.018. Epub 2012 Feb 7.

PMID:
22322296
[PubMed - indexed for MEDLINE]
Free Article
20.

Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.

Rao CV, Mohammed A, Janakiram NB, Li Q, Ritchie RL, Lightfoot S, Vibhudutta A, Steele VE.

Neoplasia. 2012 Sep;14(9):778-87.

PMID:
23019409
[PubMed - indexed for MEDLINE]
Free PMC Article
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