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Results: 1 to 20 of 137

1.

2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.

Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9. doi: 10.1016/j.taap.2012.06.010. Epub 2012 Jun 23.

PMID:
22732900
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.

Powell KL, Boulware S, Thames H, Vasquez KM, MacLeod MC.

Chem Res Toxicol. 2010 Mar 15;23(3):497-503. doi: 10.1021/tx9001918.

PMID:
20050631
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.

PMID:
21722719
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog.

Abel EL, Boulware S, Fields T, McIvor E, Powell KL, DiGiovanni J, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2013 Feb 1;266(3):439-42. doi: 10.1016/j.taap.2012.11.020. Epub 2012 Nov 30.

PMID:
23201461
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R.

Toxicol Sci. 2009 Mar;108(1):194-206. doi: 10.1093/toxsci/kfn261. Epub 2008 Dec 15.

PMID:
19075041
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ameliorating effect of S-2(ω-aminoalkylamino) alkylaryl sulfide (DRDE-07) on sulfur mustard analogue, 2-chloroethyl ethyl sulfide-induced oxidative stress and inflammation.

Sawale SD, Ambhore PD, Pawar PP, Pathak U, Deb U, Satpute RM.

Toxicol Mech Methods. 2013 Nov;23(9):702-10. doi: 10.3109/15376516.2013.843109. Epub 2013 Oct 28.

PMID:
24024669
[PubMed - indexed for MEDLINE]
7.

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

Inturi S, Tewari-Singh N, Gu M, Shrotriya S, Gomez J, Agarwal C, White CW, Agarwal R.

Free Radic Biol Med. 2011 Dec 15;51(12):2272-80. doi: 10.1016/j.freeradbiomed.2011.08.020. Epub 2011 Aug 26.

PMID:
21920433
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.

Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):176-83. doi: 10.1016/j.taap.2011.06.012. Epub 2011 Jun 23.

PMID:
21723306
[PubMed - indexed for MEDLINE]
9.

Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.

Pal A, Tewari-Singh N, Gu M, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

Free Radic Biol Med. 2009 Dec 1;47(11):1640-51. doi: 10.1016/j.freeradbiomed.2009.09.011. Epub 2009 Sep 15.

PMID:
19761830
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

PMID:
23029417
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

O'Neill HC, White CW, Veress LA, Hendry-Hofer TB, Loader JE, Min E, Huang J, Rancourt RC, Day BJ.

Free Radic Biol Med. 2010 May 1;48(9):1188-96. doi: 10.1016/j.freeradbiomed.2010.01.039. Epub 2010 Feb 4.

PMID:
20138141
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A double-label technique that monitors sulfur mustard damage to nuclei and mitochondria of normal human epidermal keratinocytes in vitro.

Cook JR, Van Buskirk RG.

Toxicol Pathol. 1997 Sep-Oct;25(5):481-6.

PMID:
9323838
[PubMed - indexed for MEDLINE]
Free Article
13.

Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.

Kehe K, Schrettl V, Thiermann H, Steinritz D.

Chem Biol Interact. 2013 Dec 5;206(3):523-8. doi: 10.1016/j.cbi.2013.08.001. Epub 2013 Aug 8.

PMID:
23933409
[PubMed - indexed for MEDLINE]
14.

Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.

Tewari-Singh N, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

J Pharmacol Exp Ther. 2011 Feb;336(2):450-9. doi: 10.1124/jpet.110.173708. Epub 2010 Oct 25. Review.

PMID:
20974699
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.

Jain AK, Tewari-Singh N, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2011 Apr 11;282(3):129-38. doi: 10.1016/j.tox.2011.01.021. Epub 2011 Feb 2.

PMID:
21295104
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Dec 1;249(2):178-87. doi: 10.1016/j.taap.2010.09.005. Epub 2010 Sep 16.

PMID:
20840853
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ.

Free Radic Biol Med. 2014 Jul;72:285-95. doi: 10.1016/j.freeradbiomed.2014.04.022. Epub 2014 May 9.

PMID:
24815113
[PubMed - in process]
18.

Biochemical changes in mouse lung after subcutaneous injection of the sulfur mustard 2-chloroethyl 4-chlorobutyl sulfide.

Elsayed NM, Omaye ST.

Toxicology. 2004 Jul 1;199(2-3):195-206.

PMID:
15147793
[PubMed - indexed for MEDLINE]
19.

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.

Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):352-60. doi: 10.1016/j.taap.2010.04.001. Epub 2010 Apr 9.

PMID:
20382172
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection.

Gould NS, White CW, Day BJ.

J Pharmacol Exp Ther. 2009 Mar;328(3):732-9. doi: 10.1124/jpet.108.145037. Epub 2008 Dec 8.

PMID:
19064720
[PubMed - indexed for MEDLINE]
Free PMC Article

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