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Results: 1 to 20 of 102

1.

Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia.

Anyona SB, Kempaiah P, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ.

Am J Hematol. 2012 Aug;87(8):782-9. doi: 10.1002/ajh.23253. Epub 2012 Jun 23.

PMID:
22730036
[PubMed - indexed for MEDLINE]
2.

Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia.

Awandare GA, Ouma Y, Ouma C, Were T, Otieno R, Keller CC, Davenport GC, Hittner JB, Vulule J, Ferrell R, Ong'echa JM, Perkins DJ.

Infect Immun. 2007 Jan;75(1):201-10. Epub 2006 Oct 23.

PMID:
17060471
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Suppression of a novel hematopoietic mediator in children with severe malarial anemia.

Keller CC, Ouma C, Ouma Y, Awandare GA, Davenport GC, Were T, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ.

Infect Immun. 2009 Sep;77(9):3864-71. doi: 10.1128/IAI.00342-09. Epub 2009 Jun 15.

PMID:
19528216
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Suppression of prostaglandin E2 by malaria parasite products and antipyretics promotes overproduction of tumor necrosis factor-alpha: association with the pathogenesis of childhood malarial anemia.

Keller CC, Davenport GC, Dickman KR, Hittner JB, Kaplan SS, Weinberg JB, Kremsner PG, Perkins DJ.

J Infect Dis. 2006 May 15;193(10):1384-93. Epub 2006 Apr 7.

PMID:
16619186
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia.

Anyona SB, Kempaiah P, Davenport GC, Vulule JM, Hittner JB, Ong'echa JM, Perkins DJ.

Biochem Biophys Res Commun. 2013 Jul 12;436(4):585-90. doi: 10.1016/j.bbrc.2013.05.089. Epub 2013 Jun 3.

PMID:
23743193
[PubMed - indexed for MEDLINE]
7.

Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia.

Keller CC, Yamo O, Ouma C, Ong'echa JM, Ounah D, Hittner JB, Vulule JM, Perkins DJ.

Infect Immun. 2006 Sep;74(9):5249-60.

PMID:
16926419
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Severe malarial anemia: innate immunity and pathogenesis.

Perkins DJ, Were T, Davenport GC, Kempaiah P, Hittner JB, Ong'echa JM.

Int J Biol Sci. 2011;7(9):1427-42. Epub 2011 Nov 2. Review.

PMID:
22110393
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.

Were T, Davenport GC, Yamo EO, Hittner JB, Awandare GA, Otieno MF, Ouma C, Orago AS, Vulule JM, Ong'echa JM, Perkins DJ.

Microbes Infect. 2009 Jul-Aug;11(8-9):811-9. doi: 10.1016/j.micinf.2009.04.021. Epub 2009 May 7.

PMID:
19427395
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.

Ouma C, Keller CC, Davenport GC, Were T, Konah S, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ.

Infect Immun. 2010 Jan;78(1):453-60. doi: 10.1128/IAI.00895-09. Epub 2009 Nov 2.

PMID:
19884328
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Impaired systemic production of prostaglandin E2 in children with cerebral malaria.

Perkins DJ, Hittner JB, Mwaikambo ED, Granger DL, Weinberg JB, Anstey NM.

J Infect Dis. 2005 May 1;191(9):1548-57. Epub 2005 Mar 31.

PMID:
15809915
[PubMed - indexed for MEDLINE]
Free Article
12.

Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model.

Awandare GA, Kempaiah P, Ochiel DO, Piazza P, Keller CC, Perkins DJ.

Am J Hematol. 2011 Feb;86(2):155-62. doi: 10.1002/ajh.21933.

PMID:
21264897
[PubMed - indexed for MEDLINE]
13.

Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV-1.

Davenport GC, Ouma C, Hittner JB, Were T, Ouma Y, Ong'echa JM, Perkins DJ.

Am J Hematol. 2010 Apr;85(4):227-33. doi: 10.1002/ajh.21653.

PMID:
20196168
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.

Novelli EM, Hittner JB, Davenport GC, Ouma C, Were T, Obaro S, Kaplan S, Ong'echa JM, Perkins DJ.

Br J Haematol. 2010 Jun;149(5):711-21. doi: 10.1111/j.1365-2141.2010.08147.x. Epub 2010 Apr 16.

PMID:
20408849
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo.

Casals-Pascual C, Kai O, Cheung JO, Williams S, Lowe B, Nyanoti M, Williams TN, Maitland K, Molyneux M, Newton CR, Peshu N, Watt SM, Roberts DJ.

Blood. 2006 Oct 15;108(8):2569-77. Epub 2006 Jun 27.

PMID:
16804108
[PubMed - indexed for MEDLINE]
Free Article
16.

Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria.

Otieno RO, Ouma C, Ong'echa JM, Keller CC, Were T, Waindi EN, Michaels MG, Day RD, Vulule JM, Perkins DJ.

AIDS. 2006 Jan 9;20(2):275-80.

PMID:
16511422
[PubMed - indexed for MEDLINE]
17.

Plasmodium products contribute to severe malarial anemia by inhibiting erythropoietin-induced proliferation of erythroid precursors.

Thawani N, Tam M, Bellemare MJ, Bohle DS, Olivier M, de Souza JB, Stevenson MM.

J Infect Dis. 2014 Jan 1;209(1):140-9. doi: 10.1093/infdis/jit417. Epub 2013 Aug 6.

PMID:
23922378
[PubMed - indexed for MEDLINE]
18.

Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods.

Ong'echa JM, Davenport GC, Vulule JM, Hittner JB, Perkins DJ.

Infect Immun. 2011 Nov;79(11):4674-80. doi: 10.1128/IAI.05161-11. Epub 2011 Aug 22.

PMID:
21859849
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production.

Ouma C, Davenport GC, Were T, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ.

Hum Genet. 2008 Dec;124(5):515-24. doi: 10.1007/s00439-008-0578-5. Epub 2008 Oct 30.

PMID:
18972133
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inverse relationship of plasma prostaglandin E2 and blood mononuclear cell cyclooxygenase-2 with disease severity in children with Plasmodium falciparum malaria.

Perkins DJ, Kremsner PG, Weinberg JB.

J Infect Dis. 2001 Jan 1;183(1):113-8. Epub 2000 Nov 13.

PMID:
11076710
[PubMed - indexed for MEDLINE]
Free Article
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