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Results: 1 to 20 of 136

1.

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints.

Irimia M, Tena JJ, Alexis MS, Fernandez-Miñan A, Maeso I, Bogdanovic O, de la Calle-Mustienes E, Roy SW, Gómez-Skarmeta JL, Fraser HB.

Genome Res. 2012 Dec;22(12):2356-67. doi: 10.1101/gr.139725.112. Epub 2012 Jun 21.

PMID:
22722344
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Genomic regulatory blocks underlie extensive microsynteny conservation in insects.

Engström PG, Ho Sui SJ, Drivenes O, Becker TS, Lenhard B.

Genome Res. 2007 Dec;17(12):1898-908. Epub 2007 Nov 7.

PMID:
17989259
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention.

Hufton AL, Mathia S, Braun H, Georgi U, Lehrach H, Vingron M, Poustka AJ, Panopoulou G.

Genome Res. 2009 Nov;19(11):2036-51. doi: 10.1101/gr.093237.109. Epub 2009 Aug 24.

PMID:
19704032
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ancient cis-regulatory constraints and the evolution of genome architecture.

Irimia M, Maeso I, Roy SW, Fraser HB.

Trends Genet. 2013 Sep;29(9):521-8. doi: 10.1016/j.tig.2013.05.008. Epub 2013 Jun 18. Review.

PMID:
23791467
[PubMed - indexed for MEDLINE]
5.

Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates.

Kikuta H, Laplante M, Navratilova P, Komisarczuk AZ, Engström PG, Fredman D, Akalin A, Caccamo M, Sealy I, Howe K, Ghislain J, Pezeron G, Mourrain P, Ellingsen S, Oates AC, Thisse C, Thisse B, Foucher I, Adolf B, Geling A, Lenhard B, Becker TS.

Genome Res. 2007 May;17(5):545-55. Epub 2007 Mar 26.

PMID:
17387144
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes.

Chatterjee S, Bourque G, Lufkin T.

BMC Dev Biol. 2011 Oct 20;11:63. doi: 10.1186/1471-213X-11-63.

PMID:
22011226
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cis-regulatory characterization of sequence conservation surrounding the Hox4 genes.

Punnamoottil B, Herrmann C, Pascual-Anaya J, D'Aniello S, Garcia-Fernàndez J, Akalin A, Becker TS, Rinkwitz S.

Dev Biol. 2010 Apr 15;340(2):269-82. doi: 10.1016/j.ydbio.2010.01.035. Epub 2010 Feb 6.

PMID:
20144609
[PubMed - indexed for MEDLINE]
Free Article
8.

Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura.

Berman BP, Pfeiffer BD, Laverty TR, Salzberg SL, Rubin GM, Eisen MB, Celniker SE.

Genome Biol. 2004;5(9):R61. Epub 2004 Aug 20.

PMID:
15345045
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Retroviral enhancer detection insertions in zebrafish combined with comparative genomics reveal genomic regulatory blocks - a fundamental feature of vertebrate genomes.

Kikuta H, Fredman D, Rinkwitz S, Lenhard B, Becker TS.

Genome Biol. 2007;8 Suppl 1:S4. Review.

PMID:
18047696
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Identification of cis regulatory features in the embryonic zebrafish genome through large-scale profiling of H3K4me1 and H3K4me3 binding sites.

Aday AW, Zhu LJ, Lakshmanan A, Wang J, Lawson ND.

Dev Biol. 2011 Sep 15;357(2):450-62. doi: 10.1016/j.ydbio.2011.03.007. Epub 2011 Mar 22.

PMID:
21435340
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Comparative genomics of ParaHox clusters of teleost fishes: gene cluster breakup and the retention of gene sets following whole genome duplications.

Siegel N, Hoegg S, Salzburger W, Braasch I, Meyer A.

BMC Genomics. 2007 Sep 6;8:312.

PMID:
17822543
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Functional tests of enhancer conservation between distantly related species.

Ruvinsky I, Ruvkun G.

Development. 2003 Nov;130(21):5133-42. Epub 2003 Aug 27.

PMID:
12944426
[PubMed - indexed for MEDLINE]
Free Article
13.

An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement.

Maeso I, Irimia M, Tena JJ, González-Pérez E, Tran D, Ravi V, Venkatesh B, Campuzano S, Gómez-Skarmeta JL, Garcia-Fernàndez J.

Genome Res. 2012 Apr;22(4):642-55. doi: 10.1101/gr.132233.111. Epub 2012 Jan 10.

PMID:
22234889
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Comparative analysis of function and interaction of transcription factors in nematodes: extensive conservation of orthology coupled to rapid sequence evolution.

Haerty W, Artieri C, Khezri N, Singh RS, Gupta BP.

BMC Genomics. 2008 Aug 27;9:399. doi: 10.1186/1471-2164-9-399.

PMID:
18752680
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular evolution of the HoxA cluster in the three major gnathostome lineages.

Chiu CH, Amemiya C, Dewar K, Kim CB, Ruddle FH, Wagner GP.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5492-7. Epub 2002 Apr 9.

PMID:
11943847
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Genomic analysis reveals extensive gene duplication within the bovine TRB locus.

Connelley T, Aerts J, Law A, Morrison WI.

BMC Genomics. 2009 Apr 24;10:192. doi: 10.1186/1471-2164-10-192.

PMID:
19393068
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Evolutionary conservation of regulatory elements in vertebrate Hox gene clusters.

Santini S, Boore JL, Meyer A.

Genome Res. 2003 Jun;13(6A):1111-22. Erratum in: Genome Res. 2003 Aug;13(8):1973.

PMID:
12799348
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs.

Starr MO, Ho MC, Gunther EJ, Tu YK, Shur AS, Goetz SE, Borok MJ, Kang V, Drewell RA.

Dev Biol. 2011 Nov 15;359(2):290-302. doi: 10.1016/j.ydbio.2011.07.028. Epub 2011 Jul 28.

PMID:
21821017
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks.

Marbach D, Roy S, Ay F, Meyer PE, Candeias R, Kahveci T, Bristow CA, Kellis M.

Genome Res. 2012 Jul;22(7):1334-49. doi: 10.1101/gr.127191.111. Epub 2012 Mar 28.

PMID:
22456606
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Correlation of microsynteny conservation and disease gene distribution in mammalian genomes.

Lovell SC, Li X, Weerasinghe NR, Hentges KE.

BMC Genomics. 2009 Nov 12;10:521. doi: 10.1186/1471-2164-10-521.

PMID:
19909546
[PubMed - indexed for MEDLINE]
Free PMC Article

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