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Items: 1 to 20 of 115

1.

Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.

Bhat AA, Sharma A, Pope J, Krishnan M, Washington MK, Singh AB, Dhawan P.

PLoS One. 2012;7(6):e37174. doi: 10.1371/journal.pone.0037174. Epub 2012 Jun 15.

2.

Repression of the desmocollin 2 gene expression in human colon cancer cells is relieved by the homeodomain transcription factors Cdx1 and Cdx2.

Funakoshi S, Ezaki T, Kong J, Guo RJ, Lynch JP.

Mol Cancer Res. 2008 Sep;6(9):1478-90. doi: 10.1158/1541-7786.MCR-07-2161.

3.

Functional crosstalk between Wnt signaling and Cdx-related transcriptional activation in the regulation of the claudin-2 promoter activity.

Mankertz J, Hillenbrand B, Tavalali S, Huber O, Fromm M, Schulzke JD.

Biochem Biophys Res Commun. 2004 Feb 20;314(4):1001-7.

PMID:
14751232
4.

Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.

Guo RJ, Huang E, Ezaki T, Patel N, Sinclair K, Wu J, Klein P, Suh ER, Lynch JP.

J Biol Chem. 2004 Aug 27;279(35):36865-75. Epub 2004 Jun 23.

5.

H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.

Song X, Chen HX, Wang XY, Deng XY, Xi YX, He Q, Peng TL, Chen J, Chen W, Wong BC, Chen MH.

Cell Immunol. 2013 Nov-Dec;286(1-2):22-30. doi: 10.1016/j.cellimm.2013.10.008. Epub 2013 Nov 9.

PMID:
24287273
6.

CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.

Kakizaki F, Aoki K, Miyoshi H, Carrasco N, Aoki M, Taketo MM.

Gastroenterology. 2010 Feb;138(2):627-35. doi: 10.1053/j.gastro.2009.10.047. Epub 2009 Nov 10.

PMID:
19900445
7.
8.

Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.

Koslowski M, Türeci O, Huber C, Sahin U.

Mol Cancer. 2009 Sep 25;8:77. doi: 10.1186/1476-4598-8-77.

9.
10.

Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis.

Mallo GV, Rechreche H, Frigerio JM, Rocha D, Zweibaum A, Lacasa M, Jordan BR, Dusetti NJ, Dagorn JC, Iovanna JL.

Int J Cancer. 1997 Feb 20;74(1):35-44.

11.

The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex.

Guo RJ, Funakoshi S, Lee HH, Kong J, Lynch JP.

Carcinogenesis. 2010 Feb;31(2):159-66. doi: 10.1093/carcin/bgp213. Epub 2009 Sep 4.

12.
13.

Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells.

Yamamichi N, Inada K, Furukawa C, Sakurai K, Tando T, Ishizaka A, Haraguchi T, Mizutani T, Fujishiro M, Shimomura R, Oka M, Ichinose M, Tsutsumi Y, Omata M, Iba H.

Exp Cell Res. 2009 Jun 10;315(10):1779-89. doi: 10.1016/j.yexcr.2009.01.006. Epub 2009 Jan 22.

PMID:
19371634
14.

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

Boudreau F, Rings EH, van Wering HM, Kim RK, Swain GP, Krasinski SD, Moffett J, Grand RJ, Suh ER, Traber PG.

J Biol Chem. 2002 Aug 30;277(35):31909-17. Epub 2002 Jun 11.

15.

Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2.

Modica S, Morgano A, Salvatore L, Petruzzelli M, Vanier MT, Valanzano R, Esposito DL, Palasciano G, Duluc I, Freund JN, Mariani-Costantini R, Moschetta A.

Gut. 2009 Sep;58(9):1250-9. doi: 10.1136/gut.2008.158386. Epub 2009 Feb 15.

PMID:
19221108
16.
17.

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.

Chan CW, Wong NA, Liu Y, Bicknell D, Turley H, Hollins L, Miller CJ, Wilding JL, Bodmer WF.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41. doi: 10.1073/pnas.0812904106. Epub 2009 Feb 2.

18.

Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells.

Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, Dhawan P.

Cancer Res. 2007 Feb 15;67(4):1571-9.

19.

Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2.

Coskun M, Olsen AK, Bzorek M, Holck S, Engel UH, Nielsen OH, Troelsen JT.

Carcinogenesis. 2014 May;35(5):1185-92. doi: 10.1093/carcin/bgu037. Epub 2014 Feb 5.

20.

Butyrate enhances intestinal epithelial barrier function via up-regulation of tight junction protein Claudin-1 transcription.

Wang HB, Wang PY, Wang X, Wan YL, Liu YC.

Dig Dis Sci. 2012 Dec;57(12):3126-35. doi: 10.1007/s10620-012-2259-4. Epub 2012 Jun 9.

PMID:
22684624
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