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Resveratrol reduces steroidogenesis in rat ovarian theca-interstitial cells: the role of inhibition of Akt/PKB signaling pathway.

Ortega I, Villanueva JA, Wong DH, Cress AB, Sokalska A, Stanley SD, Duleba AJ.

Endocrinology. 2012 Aug;153(8):4019-29. doi: 10.1210/en.2012-1385. Epub 2012 Jun 19.


Differences in neonatal exposure to estradiol or testosterone on ovarian function and hormonal levels.

Marcondes RR, Carvalho KC, Duarte DC, Garcia N, Amaral VC, Simões MJ, Lo Turco EG, Soares JM Jr, Baracat EC, Maciel GA.

Gen Comp Endocrinol. 2015 Feb 1;212:28-33. doi: 10.1016/j.ygcen.2015.01.006. Epub 2015 Jan 24.


Inhibition of CYP17A1 activity by resveratrol, piceatannol, and synthetic resveratrol analogs.

Oskarsson A, Spatafora C, Tringali C, Andersson ÅO.

Prostate. 2014 Jun;74(8):839-51. doi: 10.1002/pros.22801. Epub 2014 Mar 9.


Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis.

Ortega I, Villanueva JA, Wong DH, Cress AB, Sokalska A, Stanley SD, Duleba AJ.

J Ovarian Res. 2014 Feb 13;7:21. doi: 10.1186/1757-2215-7-21.


Comparison of effects of different statins on growth and steroidogenesis of rat ovarian theca-interstitial cells.

Sokalska A, Stanley SD, Villanueva JA, Ortega I, Duleba AJ.

Biol Reprod. 2014 Feb 27;90(2):44. doi: 10.1095/biolreprod.113.114843. Print 2014 Feb.


Growth differential factor-9 inhibits testosterone production in mouse theca interstitial cells.

Chen MH, Li T, Ding CH, Xu YW, Guo LY, Zhou CQ.

Fertil Steril. 2013 Nov;100(5):1444-50. doi: 10.1016/j.fertnstert.2013.07.200. Epub 2013 Aug 15.


Effects of granulosa cells on steroidogenesis, proliferation and apoptosis of stromal cells and theca cells derived from the goat ovary.

Qiu M, Quan F, Han C, Wu B, Liu J, Yang Z, Su F, Zhang Y.

J Steroid Biochem Mol Biol. 2013 Nov;138:325-33. doi: 10.1016/j.jsbmb.2013.06.005. Epub 2013 Jun 28.


Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.

Glister C, Satchell L, Bathgate RA, Wade JD, Dai Y, Ivell R, Anand-Ivell R, Rodgers RJ, Knight PG.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1426-35. doi: 10.1073/pnas.1222216110. Epub 2013 Mar 25.


Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary.

Ortega I, Sokalska A, Villanueva JA, Cress AB, Wong DH, Stener-Victorin E, Stanley SD, Duleba AJ.

Fertil Steril. 2013 Mar 1;99(3):889-96. doi: 10.1016/j.fertnstert.2012.11.006. Epub 2012 Nov 30.


The anti-epileptic drug valproic acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro.

Glister C, Satchell L, Michael AE, Bicknell AB, Knight PG.

PLoS One. 2012;7(11):e49553. doi: 10.1371/journal.pone.0049553. Epub 2012 Nov 12.


Effects of resveratrol on growth and function of rat ovarian granulosa cells.

Ortega I, Wong DH, Villanueva JA, Cress AB, Sokalska A, Stanley SD, Duleba AJ.

Fertil Steril. 2012 Dec;98(6):1563-73. doi: 10.1016/j.fertnstert.2012.08.004. Epub 2012 Sep 6.


Expression and effect of fibroblast growth factor 9 in bovine theca cells.

Schreiber NB, Totty ML, Spicer LJ.

J Endocrinol. 2012 Oct;215(1):167-75. doi: 10.1530/JOE-12-0293. Epub 2012 Aug 7.


Metformin inhibits human androgen production by regulating steroidogenic enzymes HSD3B2 and CYP17A1 and complex I activity of the respiratory chain.

Hirsch A, Hahn D, Kempná P, Hofer G, Nuoffer JM, Mullis PE, Flück CE.

Endocrinology. 2012 Sep;153(9):4354-66. doi: 10.1210/en.2012-1145. Epub 2012 Jul 9.


Metformin: direct inhibition of rat ovarian theca-interstitial cell proliferation.

Will MA, Palaniappan M, Peegel H, Kayampilly P, Menon KM.

Fertil Steril. 2012 Jul;98(1):207-14. doi: 10.1016/j.fertnstert.2012.04.010. Epub 2012 May 17.


Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary.

Morita Y, Wada-Hiraike O, Yano T, Shirane A, Hirano M, Hiraike H, Koyama S, Oishi H, Yoshino O, Miyamoto Y, Sone K, Oda K, Nakagawa S, Tsutsui K, Taketani Y.

Reprod Biol Endocrinol. 2012 Feb 23;10:14. doi: 10.1186/1477-7827-10-14.


Simvastatin reduces steroidogenesis by inhibiting Cyp17a1 gene expression in rat ovarian theca-interstitial cells.

Ortega I, Cress AB, Wong DH, Villanueva JA, Sokalska A, Moeller BC, Stanley SD, Duleba AJ.

Biol Reprod. 2012 Jan 30;86(1):1-9. doi: 10.1095/biolreprod.111.094714. Print 2012 Jan.


Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells.

Wong DH, Villanueva JA, Cress AB, Sokalska A, Ortega I, Duleba AJ.

Fertil Steril. 2011 Nov;96(5):1252-8. doi: 10.1016/j.fertnstert.2011.08.010. Epub 2011 Sep 9.


Theca-cell cystoma of ovary.


Am J Obstet Gynecol. 1946 Feb;51:253-9. No abstract available.


Inhibitory effect of valproic acid on ovarian androgen biosynthesis in rat theca-interstitial cells.

Fisseha S, Towns R, Harada M, Peegel H, Menon KM.

Endocrine. 2010 Feb;37(1):187-93. doi: 10.1007/s12020-009-9287-7. Epub 2009 Dec 15.

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