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Items: 1 to 20 of 102

1.

UGT1A4*3 encodes significantly increased glucuronidation of olanzapine in patients on maintenance treatment and in recombinant systems.

Haslemo T, Loryan I, Ueda N, Mannheimer B, Bertilsson L, Ingelman-Sundberg M, Molden E, Eliasson E.

Clin Pharmacol Ther. 2012 Aug;92(2):221-7. doi: 10.1038/clpt.2012.46. Epub 2012 Jun 20.

PMID:
22713701
2.

Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants.

Erickson-Ridout KK, Zhu J, Lazarus P.

Pharmacogenet Genomics. 2011 Sep;21(9):539-51. doi: 10.1097/FPC.0b013e328348c76b.

PMID:
21750471
3.
4.

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients.

Ghotbi R, Mannheimer B, Aklillu E, Suda A, Bertilsson L, Eliasson E, Osby U.

Eur J Clin Pharmacol. 2010 May;66(5):465-74. doi: 10.1007/s00228-009-0783-8. Epub 2010 Feb 9.

PMID:
20143052
5.

Oral olanzapine disposition in adolescents with schizophrenia or bipolar I disorder: a population pharmacokinetic model.

Lobo ED, Robertson-Plouch C, Quinlan T, Hong Q, Bergstrom RF.

Paediatr Drugs. 2010 Jun;12(3):201-11. doi: 10.2165/11532580-000000000-00000.

PMID:
20297865
8.

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants.

Sun D, Chen G, Dellinger RW, Duncan K, Fang JL, Lazarus P.

Breast Cancer Res. 2006;8(4):R50.

9.

Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.

Kato Y, Nakajima M, Oda S, Fukami T, Yokoi T.

Drug Metab Dispos. 2012 Feb;40(2):240-8. doi: 10.1124/dmd.111.042150. Epub 2011 Oct 25.

10.
11.

In vitro investigation of human UDP-glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: predominant contribution of UGT1A4.

Laverdière I, Caron P, Harvey M, Lévesque É, Guillemette C.

Drug Metab Dispos. 2011 Jul;39(7):1127-30. doi: 10.1124/dmd.111.039040. Epub 2011 Apr 12.

12.

Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes.

Wiener D, Fang JL, Dossett N, Lazarus P.

Cancer Res. 2004 Feb 1;64(3):1190-6. Erratum in: Cancer Res. 2004 Mar 1;64(5):1899.

13.

Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics.

Edavana VK, Dhakal IB, Williams S, Penney R, Boysen G, Yao-Borengasser A, Kadlubar S.

Drug Metab Dispos. 2013 Apr;41(4):870-7. doi: 10.1124/dmd.112.048157. Epub 2013 Jan 31.

14.

CYP1A2*1D and *1F polymorphisms have a significant impact on olanzapine serum concentrations.

Czerwensky F, Leucht S, Steimer W.

Ther Drug Monit. 2015 Apr;37(2):152-60. doi: 10.1097/FTD.0000000000000119.

PMID:
25090458
15.

Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.

Seo KA, Bae SK, Choi YK, Choi CS, Liu KH, Shin JG.

Drug Metab Dispos. 2010 Nov;38(11):2007-13. doi: 10.1124/dmd.110.035295. Epub 2010 Aug 16.

16.

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

17.

Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.

Zhou D, Guo J, Linnenbach AJ, Booth-Genthe CL, Grimm SW.

Drug Metab Dispos. 2010 May;38(5):863-70. doi: 10.1124/dmd.109.030981. Epub 2010 Feb 4.

18.
19.

The relationship between the response of clinical symptoms and plasma olanzapine concentration, based on pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP).

Nozawa M, Ohnuma T, Matsubara Y, Sakai Y, Hatano T, Hanzawa R, Shibata N, Arai H.

Ther Drug Monit. 2008 Feb;30(1):35-40. doi: 10.1097/FTD.0b013e31816336fd.

PMID:
18223460
20.

Effect of adjunctive lamotrigine treatment on the plasma concentrations of clozapine, risperidone and olanzapine in patients with schizophrenia or bipolar disorder.

Spina E, D'Arrigo C, Migliardi G, Santoro V, Muscatello MR, Micò U, D'Amico G, Perucca E.

Ther Drug Monit. 2006 Oct;28(5):599-602.

PMID:
17038872
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