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Items: 1 to 20 of 249

1.

Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia.

Baer C, Claus R, Frenzel LP, Zucknick M, Park YJ, Gu L, Weichenhan D, Fischer M, Pallasch CP, Herpel E, Rehli M, Byrd JC, Wendtner CM, Plass C.

Cancer Res. 2012 Aug 1;72(15):3775-85. Epub 2012 Jun 18.

2.

Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia--implications on constitutive activation of NFκB pathway.

Wang LQ, Kwong YL, Kho CS, Wong KF, Wong KY, Ferracin M, Calin GA, Chim CS.

Mol Cancer. 2013 Dec 27;12:173. doi: 10.1186/1476-4598-12-173.

3.

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.

Tong WG, Wierda WG, Lin E, Kuang SQ, Bekele BN, Estrov Z, Wei Y, Yang H, Keating MJ, Garcia-Manero G.

Epigenetics. 2010 Aug 16;5(6):499-508. Epub 2010 Aug 16.

4.

Uncovering the DNA methylome in chronic lymphocytic leukemia.

Cahill N, Rosenquist R.

Epigenetics. 2013 Feb;8(2):138-48. doi: 10.4161/epi.23439. Epub 2013 Jan 15. Review.

5.

Genome-wide epigenetic regulation of miRNAs in cancer.

Baer C, Claus R, Plass C.

Cancer Res. 2013 Jan 15;73(2):473-7. doi: 10.1158/0008-5472.CAN-12-3731. Epub 2013 Jan 10. Review.

6.

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.

Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM.

Blood. 2009 Oct 8;114(15):3255-64. doi: 10.1182/blood-2009-06-229898. Epub 2009 Aug 19.

7.

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.

Pei L, Choi JH, Liu J, Lee EJ, McCarthy B, Wilson JM, Speir E, Awan F, Tae H, Arthur G, Schnabel JL, Taylor KH, Wang X, Xu D, Ding HF, Munn DH, Caldwell C, Shi H.

Epigenetics. 2012 Jun 1;7(6):567-78. doi: 10.4161/epi.20237. Epub 2012 Jun 1.

8.

DNA methylation of tumor-suppressor miRNA genes in chronic lymphocytic leukemia.

Wang LQ, Chim CS.

Epigenomics. 2015;7(3):461-73. doi: 10.2217/epi.15.6. Epub 2015 Feb 4. Review.

PMID:
25650645
9.

Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets.

Rush LJ, Raval A, Funchain P, Johnson AJ, Smith L, Lucas DM, Bembea M, Liu TH, Heerema NA, Rassenti L, Liyanarachchi S, Davuluri R, Byrd JC, Plass C.

Cancer Res. 2004 Apr 1;64(7):2424-33.

10.

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer.

Wee EJ, Peters K, Nair SS, Hulf T, Stein S, Wagner S, Bailey P, Lee SY, Qu WJ, Brewster B, French JD, Dobrovic A, Francis GD, Clark SJ, Brown MA.

Oncogene. 2012 Sep 20;31(38):4182-95. doi: 10.1038/onc.2011.584. Epub 2012 Jan 9.

11.

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia.

Vargova K, Curik N, Burda P, Basova P, Kulvait V, Pospisil V, Savvulidi F, Kokavec J, Necas E, Berkova A, Obrtlikova P, Karban J, Mraz M, Pospisilova S, Mayer J, Trneny M, Zavadil J, Stopka T.

Blood. 2011 Apr 7;117(14):3816-25. doi: 10.1182/blood-2010-05-285064. Epub 2011 Feb 4.

12.

Epigenetic inactivation of mir-34b/c in addition to mir-34a and DAPK1 in chronic lymphocytic leukemia.

Wang LQ, Kwong YL, Wong KF, Kho CS, Jin DY, Tse E, Rosèn A, Chim CS.

J Transl Med. 2014 Feb 22;12:52. doi: 10.1186/1479-5876-12-52.

13.

MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma.

Wiklund ED, Gao S, Hulf T, Sibbritt T, Nair S, Costea DE, Villadsen SB, Bakholdt V, Bramsen JB, Sørensen JA, Krogdahl A, Clark SJ, Kjems J.

PLoS One. 2011;6(11):e27840. doi: 10.1371/journal.pone.0027840. Epub 2011 Nov 22.

14.

Aberrant microRNA expression in Chinese patients with chronic lymphocytic leukemia.

Zhu DX, Miao KR, Fang C, Fan L, Zhu W, Zhu HY, Zhuang Y, Hong M, Liu P, Xu W, Li JY.

Leuk Res. 2011 Jun;35(6):730-4. doi: 10.1016/j.leukres.2010.11.005. Epub 2010 Dec 3.

PMID:
21130495
15.

Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia.

Kanduri M, Cahill N, Göransson H, Enström C, Ryan F, Isaksson A, Rosenquist R.

Blood. 2010 Jan 14;115(2):296-305. doi: 10.1182/blood-2009-07-232868. Epub 2009 Nov 6. Erratum in: Blood. 2014 Jan 9;123(2):300.

16.

Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma.

Rinaldi A, Mensah AA, Kwee I, Forconi F, Orlandi EM, Lucioni M, Gattei V, Marasca R, Berger F, Cogliatti S, Cavalli F, Zucca E, Gaidano G, Rossi D, Bertoni F.

Br J Haematol. 2013 Oct;163(2):194-204. doi: 10.1111/bjh.12515. Epub 2013 Aug 21.

PMID:
23961875
17.

450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.

Cahill N, Bergh AC, Kanduri M, Göransson-Kultima H, Mansouri L, Isaksson A, Ryan F, Smedby KE, Juliusson G, Sundström C, Rosén A, Rosenquist R.

Leukemia. 2013 Jan;27(1):150-8. doi: 10.1038/leu.2012.245. Epub 2012 Aug 27.

PMID:
22922567
18.

Critical role of microRNAs in chronic lymphocytic leukemia: overexpression of the oncogene PLAG1 by deregulated miRNAs.

Patz M, Pallasch CP, Wendtner CM.

Leuk Lymphoma. 2010 Aug;51(8):1379-81. doi: 10.3109/10428194.2010.496016.

PMID:
20687796
19.
20.

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia.

Claus R, Lucas DM, Stilgenbauer S, Ruppert AS, Yu L, Zucknick M, Mertens D, Bühler A, Oakes CC, Larson RA, Kay NE, Jelinek DF, Kipps TJ, Rassenti LZ, Gribben JG, Döhner H, Heerema NA, Marcucci G, Plass C, Byrd JC.

J Clin Oncol. 2012 Jul 10;30(20):2483-91. doi: 10.1200/JCO.2011.39.3090. Epub 2012 May 7.

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