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Items: 1 to 20 of 79

1.

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125.

Caporali S, Alvino E, Levati L, Esposito AI, Ciomei M, Brasca MG, Del Bufalo D, Desideri M, Bonmassar E, Pfeffer U, D'Atri S.

Biochem Pharmacol. 2012 Sep 1;84(5):598-611. doi: 10.1016/j.bcp.2012.06.004. Epub 2012 Jun 13.

PMID:
22704958
2.

The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.

Caporali S, Alvino E, Starace G, Ciomei M, Brasca MG, Levati L, Garbin A, Castiglia D, Covaciu C, Bonmassar E, D'Atri S.

Pharmacol Res. 2010 May;61(5):437-48. doi: 10.1016/j.phrs.2009.12.009. Epub 2009 Dec 21.

PMID:
20026273
3.

Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.

Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F.

Mol Cancer Res. 2008 Jan;6(1):42-52. doi: 10.1158/1541-7786.MCR-07-0080.

5.

Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.

Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH.

Oncogene. 2001 May 24;20(23):2927-36.

6.
7.

Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells.

Lin SY, Lai WW, Chou CC, Kuo HM, Li TM, Chung JG, Yang JH.

Melanoma Res. 2006 Dec;16(6):509-19.

PMID:
17119452
8.

Myc down-regulation sensitizes melanoma cells to radiotherapy by inhibiting MLH1 and MSH2 mismatch repair proteins.

Bucci B, D'Agnano I, Amendola D, Citti A, Raza GH, Miceli R, De Paula U, Marchese R, Albini S, Felsani A, Brunetti E, Vecchione A.

Clin Cancer Res. 2005 Apr 1;11(7):2756-67.

9.

Dual targeting of CDK and tropomyosin receptor kinase families by the oral inhibitor PHA-848125, an agent with broad-spectrum antitumor efficacy.

Albanese C, Alzani R, Amboldi N, Avanzi N, Ballinari D, Brasca MG, Festuccia C, Fiorentini F, Locatelli G, Pastori W, Patton V, Roletto F, Colotta F, Galvani A, Isacchi A, Moll J, Pesenti E, Mercurio C, Ciomei M.

Mol Cancer Ther. 2010 Aug;9(8):2243-54. doi: 10.1158/1535-7163.MCT-10-0190. Epub 2010 Aug 3.

11.

Adenovirus-mediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells.

Dong YB, Yang HL, Elliott MJ, Liu TJ, Stilwell A, Atienza C Jr, McMasters KM.

Cancer. 1999 Nov 15;86(10):2021-33.

PMID:
10570427
13.

Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival.

Flørenes VA, Skrede M, Jørgensen K, Nesland JM.

Melanoma Res. 2004 Jun;14(3):173-81.

PMID:
15179185
14.

Role of the pituitary tumor transforming gene 1 in the progression of hepatocellular carcinoma.

Liang M, Chen X, Liu W, Li S, Li C, Jiang L, Lv S.

Cancer Biol Ther. 2011 Feb 1;11(3):337-45. Epub 2011 Feb 1.

PMID:
21099350
15.

Ultraviolet radiation down-regulates expression of the cell-cycle inhibitor p21WAF1/CIP1 in human cancer cells independently of p53.

Wang JA, Fan S, Yuan RQ, Ma YX, Meng Q, Goldberg ID, Rosen EM.

Int J Radiat Biol. 1999 Mar;75(3):301-16.

PMID:
10203181
16.

Antiproliferative effect of IL-1 is mediated by p38 mitogen-activated protein kinase in human melanoma cell A375.

Itoh S, Hattori T, Hayashi H, Mizutani Y, Todo M, Takii T, Yang D, Lee JC, Matsufuji S, Murakami Y, Chiba T, Onozaki K.

J Immunol. 1999 Jun 15;162(12):7434-40.

17.
18.

Ircinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells.

Choi HJ, Choi YH, Yee SB, Im E, Jung JH, Kim ND.

Mol Carcinog. 2005 Nov;44(3):162-73.

PMID:
16163705
20.
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