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Results: 1 to 20 of 164

1.

Matrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels.

Meighan PC, Meighan SE, Rich ED, Brown RL, Varnum MD.

Channels (Austin). 2012 May-Jun;6(3):181-96. doi: 10.4161/chan.20904. Epub 2012 May 1.

PMID:
22699690
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating.

Meighan SE, Meighan PC, Rich ED, Brown RL, Varnum MD.

Biochemistry. 2013 Nov 19;52(46):8352-62. doi: 10.1021/bi400824x. Epub 2013 Nov 11.

PMID:
24164424
[PubMed - indexed for MEDLINE]
3.

Tuning outer segment Ca2+ homeostasis to phototransduction in rods and cones.

Korenbrot JI, Rebrik TI.

Adv Exp Med Biol. 2002;514:179-203. Review.

PMID:
12596922
[PubMed - indexed for MEDLINE]
4.
5.

Tyrosine phosphorylation of rod cyclic nucleotide-gated channels switches off Ca2+/calmodulin inhibition.

Krajewski JL, Luetje CW, Kramer RH.

J Neurosci. 2003 Nov 5;23(31):10100-6.

PMID:
14602825
[PubMed - indexed for MEDLINE]
Free Article
6.

Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides.

Dai G, Peng C, Liu C, Varnum MD.

J Gen Physiol. 2013 Apr;141(4):413-30. doi: 10.1085/jgp.201210944.

PMID:
23530136
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

CNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactions.

Dai G, Varnum MD.

Am J Physiol Cell Physiol. 2013 Jul 15;305(2):C147-59. doi: 10.1152/ajpcell.00037.2013. Epub 2013 Apr 3.

PMID:
23552282
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cyclic nucleotide-gated channels.

Biel M, Michalakis S.

Handb Exp Pharmacol. 2009;(191):111-36. doi: 10.1007/978-3-540-68964-5_7. Review.

PMID:
19089328
[PubMed - indexed for MEDLINE]
9.

Activity-dependent modulation of rod photoreceptor cyclic nucleotide-gated channels mediated by phosphorylation of a specific tyrosine residue.

Molokanova E, Maddox F, Luetje CW, Kramer RH.

J Neurosci. 1999 Jun 15;19(12):4786-95.

PMID:
10366613
[PubMed - indexed for MEDLINE]
Free Article
10.

Disease-associated mutations in CNGB3 promote cytotoxicity in photoreceptor-derived cells.

Liu C, Sherpa T, Varnum MD.

Mol Vis. 2013 Jun 11;19:1268-81. Print 2013.

PMID:
23805033
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CNG-modulin: a novel Ca-dependent modulator of ligand sensitivity in cone photoreceptor cGMP-gated ion channels.

Rebrik TI, Botchkina I, Arshavsky VY, Craft CM, Korenbrot JI.

J Neurosci. 2012 Feb 29;32(9):3142-53. doi: 10.1523/JNEUROSCI.5518-11.2012.

PMID:
22378887
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function.

Xu J, Morris L, Thapa A, Ma H, Michalakis S, Biel M, Baehr W, Peshenko IV, Dizhoor AM, Ding XQ.

J Neurosci. 2013 Sep 11;33(37):14939-48. doi: 10.1523/JNEUROSCI.0909-13.2013.

PMID:
24027293
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Subunit contributions to phosphorylation-dependent modulation of bovine rod cyclic nucleotide-gated channels.

Molokanova E, Krajewski JL, Satpaev D, Luetje CW, Kramer RH.

J Physiol. 2003 Oct 15;552(Pt 2):345-56.

PMID:
14561819
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Altered ligand specificity by protonation in the ligand binding domain of cyclic nucleotide-gated channels.

Gordon SE, Oakley JC, Varnum MD, Zagotta WN.

Biochemistry. 1996 Apr 2;35(13):3994-4001.

PMID:
8672432
[PubMed - indexed for MEDLINE]
15.
16.

Interactions of cyclic nucleotide-gated channel subunits and protein tyrosine kinase probed with genistein.

Molokanova E, Savchenko A, Kramer RH.

J Gen Physiol. 2000 Jun;115(6):685-96.

PMID:
10828243
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

In intact mammalian photoreceptors, Ca2+-dependent modulation of cGMP-gated ion channels is detectable in cones but not in rods.

Rebrik TI, Korenbrot JI.

J Gen Physiol. 2004 Jan;123(1):63-75.

PMID:
14699078
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interdomain interactions underlying activation of cyclic nucleotide-gated channels.

Varnum MD, Zagotta WN.

Science. 1997 Oct 3;278(5335):110-3.

PMID:
9311913
[PubMed - indexed for MEDLINE]
Free Article
19.

All-trans-retinal is a closed-state inhibitor of rod cyclic nucleotide-gated ion channels.

McCabe SL, Pelosi DM, Tetreault M, Miri A, Nguitragool W, Kovithvathanaphong P, Mahajan R, Zimmerman AL.

J Gen Physiol. 2004 May;123(5):521-31. Epub 2004 Apr 12.

PMID:
15078915
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Functional role of hCngb3 in regulation of human cone cng channel: effect of rod monochromacy-associated mutations in hCNGB3 on channel function.

Okada A, Ueyama H, Toyoda F, Oda S, Ding WG, Tanabe S, Yamade S, Matsuura H, Ohkubo I, Kani K.

Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2324-32.

PMID:
15223812
[PubMed - indexed for MEDLINE]
Free Article
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