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Results: 1 to 20 of 95

1.

Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.

Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, Rajagopalan KN, Maddie M, Vemireddy V, Zhao Z, Cai L, Good L, Tu BP, Hatanpaa KJ, Mickey BE, Matés JM, Pascual JM, Maher EA, Malloy CR, Deberardinis RJ, Bachoo RM.

Cell Metab. 2012 Jun 6;15(6):827-37. doi: 10.1016/j.cmet.2012.05.001. Erratum in: Cell Metab. 2012 Nov 7;16(5):686.

PMID:
22682223
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.

Marin-Valencia I, Cho SK, Rakheja D, Hatanpaa KJ, Kapur P, Mashimo T, Jindal A, Vemireddy V, Good LB, Raisanen J, Sun X, Mickey B, Choi C, Takahashi M, Togao O, Pascual JM, Deberardinis RJ, Maher EA, Malloy CR, Bachoo RM.

NMR Biomed. 2012 Oct;25(10):1177-86. doi: 10.1002/nbm.2787. Epub 2012 Mar 1.

PMID:
22383401
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Metabolism of [U-13 C]glucose in human brain tumors in vivo.

Maher EA, Marin-Valencia I, Bachoo RM, Mashimo T, Raisanen J, Hatanpaa KJ, Jindal A, Jeffrey FM, Choi C, Madden C, Mathews D, Pascual JM, Mickey BE, Malloy CR, DeBerardinis RJ.

NMR Biomed. 2012 Nov;25(11):1234-44. doi: 10.1002/nbm.2794. Epub 2012 Mar 15.

PMID:
22419606
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.

Cheng T, Sudderth J, Yang C, Mullen AR, Jin ES, Matés JM, DeBerardinis RJ.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8674-9. doi: 10.1073/pnas.1016627108. Epub 2011 May 9.

PMID:
21555572
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.

DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19345-50. Epub 2007 Nov 21.

PMID:
18032601
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.

Yang C, Sudderth J, Dang T, Bachoo RM, McDonald JG, DeBerardinis RJ.

Cancer Res. 2009 Oct 15;69(20):7986-93. doi: 10.1158/0008-5472.CAN-09-2266. Epub 2009 Oct 13. Erratum in: Cancer Res. 2010 Feb 1;70(3):1275. Bachoo, Robert G [corrected to Bachoo, Robert M].

PMID:
19826036
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.

Eloqayli H, Melø TM, Haukvik A, Sonnewald U.

Neurochem Res. 2011 Aug;36(8):1566-73. doi: 10.1007/s11064-011-0485-3. Epub 2011 May 3.

PMID:
21538079
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells.

Monticone M, Daga A, Candiani S, Romeo F, Mirisola V, Viaggi S, Melloni I, Pedemonte S, Zona G, Giaretti W, Pfeffer U, Castagnola P.

BMC Cancer. 2012 Aug 17;12:358. doi: 10.1186/1471-2407-12-358.

PMID:
22901239
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment.

Miccoli L, Poirson-Bichat F, Sureau F, Bras Gonçalves R, Bourgeois Y, Dutrillaux B, Poupon MF, Oudard S.

J Natl Cancer Inst. 1998 Sep 16;90(18):1400-6.

PMID:
9747871
[PubMed - indexed for MEDLINE]
Free Article
10.

Combining metabolic flux analysis tools and 13C NMR to estimate intracellular fluxes of cultured astrocytes.

Teixeira AP, Santos SS, Carinhas N, Oliveira R, Alves PM.

Neurochem Int. 2008 Feb;52(3):478-86. Epub 2007 Aug 19.

PMID:
17904693
[PubMed - indexed for MEDLINE]
11.

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.

Wakimoto H, Mohapatra G, Kanai R, Curry WT Jr, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD.

Neuro Oncol. 2012 Feb;14(2):132-44. doi: 10.1093/neuonc/nor195. Epub 2011 Nov 7.

PMID:
22067563
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Pyruvate kinase and the interaction of amino acid and carbohydrate metabolism in solid tumors.

Eigenbrodt E, Kallinowski F, Ott M, Mazurek S, Vaupel P.

Anticancer Res. 1998 Sep-Oct;18(5A):3267-74.

PMID:
9858894
[PubMed - indexed for MEDLINE]
14.

Metabolic modulation of glioblastoma with dichloroacetate.

Michelakis ED, Sutendra G, Dromparis P, Webster L, Haromy A, Niven E, Maguire C, Gammer TL, Mackey JR, Fulton D, Abdulkarim B, McMurtry MS, Petruk KC.

Sci Transl Med. 2010 May 12;2(31):31ra34. doi: 10.1126/scitranslmed.3000677.

PMID:
20463368
[PubMed - indexed for MEDLINE]
Free Article
15.

Girdin maintains the stemness of glioblastoma stem cells.

Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, Ohka F, Motomura K, Kondo Y, Miyata T, Takahashi M, Wakabayashi T.

Oncogene. 2012 May 31;31(22):2715-24. doi: 10.1038/onc.2011.466. Epub 2011 Oct 24.

PMID:
22020337
[PubMed - indexed for MEDLINE]
16.

Glycolytic, glutaminolytic and pentose-phosphate pathways in promyelocytic HL60 and DMSO-differentiated HL60 cells.

Ahmed N, Williams JF, Weidemann MJ.

Biochem Mol Biol Int. 1993 Apr;29(6):1055-67.

PMID:
8330014
[PubMed - indexed for MEDLINE]
17.

Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway.

Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, Wexler E, Saigusa K, Nakamura Y, Laks DR, Mischel PS, Viapiano M, Kornblum HI.

Neuro Oncol. 2011 Jun;13(6):622-34. doi: 10.1093/neuonc/nor023. Epub 2011 May 9.

PMID:
21558073
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells.

Neermann J, Wagner R.

J Cell Physiol. 1996 Jan;166(1):152-69.

PMID:
8557765
[PubMed - indexed for MEDLINE]
19.

Mitochondrial metabolism of glutamine and glutamate and its physiological significance.

Kovacevic Z, McGivan JD.

Physiol Rev. 1983 Apr;63(2):547-605. Review. No abstract available.

PMID:
6132422
[PubMed - indexed for MEDLINE]
20.

ENTPD5-mediated modulation of ATP results in altered metabolism and decreased survival in gliomablastoma multiforme.

Zadran S, Amighi A, Otiniano E, Wong K, Zadran H.

Tumour Biol. 2012 Dec;33(6):2411-21. doi: 10.1007/s13277-012-0505-1. Epub 2012 Sep 20.

PMID:
22992974
[PubMed - indexed for MEDLINE]

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