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Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.

Yu H, Venkatesha SH, Moudgil KD.

Int Immunopharmacol. 2012 Aug;13(4):499-506. doi: 10.1016/j.intimp.2012.05.015. Epub 2012 Jun 2.


Celastrus treatment modulates antigen-induced gene expression in lymphoid cells of arthritic rats.

Yu H, Venkatesha SH, Nanjundaiah S, Tong L, Moudgil KD.

Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):455-66.


Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines.

Venkatesha SH, Astry B, Nanjundaiah SM, Yu H, Moudgil KD.

Bioorg Med Chem. 2012 Sep 1;20(17):5229-34. doi: 10.1016/j.bmc.2012.06.050. Epub 2012 Jul 7.


Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses.

Venkatesha SH, Yu H, Rajaiah R, Tong L, Moudgil KD.

J Biol Chem. 2011 Apr 29;286(17):15138-46. doi: 10.1074/jbc.M111.226365. Epub 2011 Mar 14.


Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talk.

Nanjundaiah SM, Venkatesha SH, Yu H, Tong L, Stains JP, Moudgil KD.

J Biol Chem. 2012 Jun 22;287(26):22216-26. doi: 10.1074/jbc.M112.356816. Epub 2012 May 1.


The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge.

Yu H, Lu C, Tan MT, Moudgil KD.

Arthritis Res Ther. 2011;13(5):R143. doi: 10.1186/ar3457. Epub 2011 Sep 13.


Comparative antigen-induced gene expression profiles unveil novel aspects of susceptibility/resistance to adjuvant arthritis in rats.

Yu H, Lu C, Tan MT, Moudgil KD.

Mol Immunol. 2013 Dec;56(4):531-9. doi: 10.1016/j.molimm.2013.05.230. Epub 2013 Aug 1.


Microarray analysis reveals the molecular basis of antiarthritic activity of huo-luo-xiao-ling dan.

Yu H, Lee DY, Nanjundaiah SM, Venkatesha SH, Berman BM, Moudgil KD.

Evid Based Complement Alternat Med. 2013;2013:524746. doi: 10.1155/2013/524746. Epub 2013 Jul 30.


Effective treatment of rat adjuvant-induced arthritis by celastrol.

Casc√£o R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF.

Autoimmun Rev. 2012 Oct;11(12):856-62. doi: 10.1016/j.autrev.2012.02.022. Epub 2012 Mar 3.


Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance.

Lu Y, Xiao J, Wu ZW, Wang ZM, Hu J, Fu HZ, Chen YY, Qian RQ.

Phytomedicine. 2012 Jul 15;19(10):882-9. doi: 10.1016/j.phymed.2012.04.010. Epub 2012 Jun 4.


Topical dermal application of essential oils attenuates the severity of adjuvant arthritis in Lewis rats.

Komeh-Nkrumah SA, Nanjundaiah SM, Rajaiah R, Yu H, Moudgil KD.

Phytother Res. 2012 Jan;26(1):54-9. doi: 10.1002/ptr.3509. Epub 2011 May 5.


Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis.

Rioja I, Clayton CL, Graham SJ, Life PF, Dickson MC.

Arthritis Res Ther. 2005;7(1):R101-17. Epub 2004 Nov 19.


Self heat-shock protein 65-mediated regulation of autoimmune arthritis.

Durai M, Huang MN, Moudgil KD.

J Autoimmun. 2009 Nov-Dec;33(3-4):208-13. doi: 10.1016/j.jaut.2009.09.007. Epub 2009 Oct 2.

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