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Items: 1 to 20 of 193

1.

Gene repair of an Usher syndrome causing mutation by zinc-finger nuclease mediated homologous recombination.

Overlack N, Goldmann T, Wolfrum U, Nagel-Wolfrum K.

Invest Ophthalmol Vis Sci. 2012 Jun 26;53(7):4140-6. doi: 10.1167/iovs.12-9812.

PMID:
22661463
2.

Beneficial read-through of a USH1C nonsense mutation by designed aminoglycoside NB30 in the retina.

Goldmann T, Rebibo-Sabbah A, Overlack N, Nudelman I, Belakhov V, Baasov T, Ben-Yosef T, Wolfrum U, Nagel-Wolfrum K.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6671-80. doi: 10.1167/iovs.10-5741. Epub 2010 Jul 29.

PMID:
20671281
3.

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.

Reiners J, Nagel-Wolfrum K, Jürgens K, Märker T, Wolfrum U.

Exp Eye Res. 2006 Jul;83(1):97-119. Epub 2006 Mar 20. Review.

PMID:
16545802
4.

Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases.

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S.

DNA Repair (Amst). 2009 Mar 1;8(3):298-308. doi: 10.1016/j.dnarep.2008.11.011. Epub 2008 Dec 30.

PMID:
19071233
5.

Quantification of zinc finger nuclease-associated toxicity.

Cornu TI, Cathomen T.

Methods Mol Biol. 2010;649:237-45. doi: 10.1007/978-1-60761-753-2_14.

PMID:
20680838
6.

Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast.

Ren C, Yan Q, Zhang Z.

Mol Biol Rep. 2014 Oct;41(10):6939-48. doi: 10.1007/s11033-014-3579-6. Epub 2014 Jul 15.

PMID:
25024047
7.

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK.

PLoS One. 2009;4(2):e4348. doi: 10.1371/journal.pone.0004348. Epub 2009 Feb 9.

8.

Novel mutations in the USH1C gene in Usher syndrome patients.

Aparisi MJ, García-García G, Jaijo T, Rodrigo R, Graziano C, Seri M, Simsek T, Simsek E, Bernal S, Baiget M, Pérez-Garrigues H, Aller E, Millán JM.

Mol Vis. 2010 Dec 31;16:2948-54.

9.

A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells.

Tovkach A, Zeevi V, Tzfira T.

Plant J. 2009 Feb;57(4):747-57. doi: 10.1111/j.1365-313X.2008.03718.x. Epub 2008 Nov 24.

PMID:
18980651
10.

Therapy strategies for Usher syndrome Type 1C in the retina.

Nagel-Wolfrum K, Baasov T, Wolfrum U.

Adv Exp Med Biol. 2014;801:741-7. doi: 10.1007/978-1-4614-3209-8_93. Review.

PMID:
24664766
11.

Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases.

Kawai N, Ochiai H, Sakuma T, Yamada L, Sawada H, Yamamoto T, Sasakura Y.

Dev Growth Differ. 2012 Jun;54(5):535-45. doi: 10.1111/j.1440-169X.2012.01355.x. Epub 2012 May 28.

PMID:
22640377
12.

ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.

Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR.

BMC Genomics. 2011 Jan 28;12:83. doi: 10.1186/1471-2164-12-83.

13.

Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector.

Abarrategui-Pontes C, Créneguy A, Thinard R, Fine EJ, Thepenier V, Fournier le RL, Cradick TJ, Bao G, Tesson L, Podevin G, Anegon I, Nguyen TH.

Curr Gene Ther. 2014;14(5):365-76.

PMID:
25687502
14.

Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications.

Radecke S, Radecke F, Cathomen T, Schwarz K.

Mol Ther. 2010 Apr;18(4):743-53. doi: 10.1038/mt.2009.304. Epub 2010 Jan 12.

15.

Sandwiched zinc-finger nucleases demonstrating higher homologous recombination rates than conventional zinc-finger nucleases in mammalian cells.

Mori T, Mori K, Tobimatsu T, Sera T.

Bioorg Med Chem Lett. 2014 Feb 1;24(3):813-6. doi: 10.1016/j.bmcl.2013.12.096. Epub 2014 Jan 3.

PMID:
24412074
16.

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.

Reiners J, van Wijk E, Märker T, Zimmermann U, Jürgens K, te Brinke H, Overlack N, Roepman R, Knipper M, Kremer H, Wolfrum U.

Hum Mol Genet. 2005 Dec 15;14(24):3933-43. Epub 2005 Nov 21.

17.

A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets.

Hoshaw JP, Unger-Wallace E, Zhang F, Voytas DF.

Methods Mol Biol. 2010;649:299-313. doi: 10.1007/978-1-60761-753-2_19.

PMID:
20680843
18.

Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways.

Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF.

Genome Res. 2013 Mar;23(3):547-54. doi: 10.1101/gr.145557.112. Epub 2013 Jan 2.

19.

Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.

20.

Creating designed zinc-finger nucleases with minimal cytotoxicity.

Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S.

J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19.

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