Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 110

1.

Optimising conditions for studying the acute effects of drugs on indices of cardiac contractility and on haemodynamics in anaesthetized guinea pigs.

Mooney L, Marks L, Philp KL, Skinner M, Coker SJ, Currie S.

J Pharmacol Toxicol Methods. 2012 Jul;66(1):43-51. doi: 10.1016/j.vascn.2012.05.008. Epub 2012 May 30.

PMID:
22659057
[PubMed - indexed for MEDLINE]
2.

Drug-induced effects on cardiovascular function in pentobarbital anesthetized guinea-pigs: invasive LVP measurements versus the QA interval.

Johnson DM, Geys R, Lissens J, Guns PJ.

J Pharmacol Toxicol Methods. 2012 Sep;66(2):152-9. doi: 10.1016/j.vascn.2012.07.002. Epub 2012 Jul 17.

PMID:
22813982
[PubMed - indexed for MEDLINE]
3.

Cardiovascular parameters in anaesthetized guinea pigs: a safety pharmacology screening model.

Hauser DS, Stade M, Schmidt A, Hanauer G.

J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):106-14.

PMID:
15961325
[PubMed - indexed for MEDLINE]
4.

Assessment of the pharmacological effects of inotropic drugs on left ventricular pressure and contractility: an evaluation of the QA interval as an indirect indicator of cardiac inotropism.

Norton K, Iacono G, Vezina M.

J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):193-7. doi: 10.1016/j.vascn.2009.05.008. Epub 2009 Jun 10.

PMID:
19523528
[PubMed - indexed for MEDLINE]
5.

QA interval as an indirect measure of cardiac contractility in the conscious telemeterised rat: model optimisation and evaluation.

Adeyemi O, Roberts S, Harris J, West H, Shome S, Dewhurst M.

J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):159-66. doi: 10.1016/j.vascn.2009.03.006. Epub 2009 Jul 16.

PMID:
19616109
[PubMed - indexed for MEDLINE]
6.

The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds.

Marks L, Borland S, Philp K, Ewart L, Lainée P, Skinner M, Kirk S, Valentin JP.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):171-83. doi: 10.1016/j.taap.2012.06.007. Epub 2012 Jun 17.

PMID:
22714037
[PubMed - indexed for MEDLINE]
7.

Evaluation of a method to correct the contractility index LVdP/dt(max) for changes in heart rate.

Markert M, Trautmann T, Groß M, Ege A, Mayer K, Guth B.

J Pharmacol Toxicol Methods. 2012 Sep;66(2):98-105. doi: 10.1016/j.vascn.2012.04.005. Epub 2012 Apr 23.

PMID:
22554385
[PubMed - indexed for MEDLINE]
8.

A translational assessment of preclinical versus clinical tools for the measurement of cardiac contractility: comparison of LV dP/dt(max) with echocardiography in telemetry implanted beagle dogs.

Cools F, Dhuyvetter D, Vanlommel A, Janssens S, Borghys H, Geys H, Gallacher DJ.

J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):17-23. doi: 10.1016/j.vascn.2013.10.003. Epub 2013 Oct 16.

PMID:
24140387
[PubMed - indexed for MEDLINE]
9.
10.
11.

In-vivo effects of amrinone and milrinone on left ventricular dP/dt, intraventricular pressure and heart rate in pentobarbital-anesthetized guinea pigs.

Lin BB, Chen HL.

Res Commun Chem Pathol Pharmacol. 1991 Nov;74(2):237-40.

PMID:
1811284
[PubMed - indexed for MEDLINE]
12.

Effects of AL 107, a novel semisynthetic cardiac glycoside, on the cardiovascular system in anaesthetized beagle dogs with pentobarbital-induced cardiac insufficiency.

Kögel B, Schneider J, Gleitz J, Wilffert B, Peters T.

Arzneimittelforschung. 1999 Aug;49(8):679-84.

PMID:
10483514
[PubMed - indexed for MEDLINE]
13.

Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine.

Grund F, Tjomsland O, Sjaastad I, Ilebekk A, Kirkebøen KA.

Lab Anim. 2004 Jan;38(1):70-8.

PMID:
14979991
[PubMed - indexed for MEDLINE]
14.

The effects of levosimendan on myocardial function in ropivacaine toxicity in isolated guinea pig heart preparations.

Stehr SN, Christ T, Rasche B, Rasche S, Wettwer E, Deussen A, Ravens U, Koch T, Hübler M.

Anesth Analg. 2007 Sep;105(3):641-7.

PMID:
17717217
[PubMed - indexed for MEDLINE]
15.

The value added by measuring myocardial contractility 'in vivo' in safety pharmacological profiling of drug candidates.

Markert M, Klumpp A, Trautmann T, Mayer K, Stubhan M, Guth B.

J Pharmacol Toxicol Methods. 2007 Sep-Oct;56(2):203-11. Epub 2007 May 24.

PMID:
17583538
[PubMed - indexed for MEDLINE]
16.

Direct negative inotropic and lusitropic effects of sevoflurane.

Harkin CP, Pagel PS, Kersten JR, Hettrick DA, Warltier DC.

Anesthesiology. 1994 Jul;81(1):156-67. Erratum in: Anesthesiology 1994 Oct;81(4):1080.

PMID:
8042785
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

A dose-response study of levosimendan in a porcine model of acute ischaemic heart failure.

Kolseth SM, Wahba A, Kirkeby-Garstad I, Aro S, Nordgaard H, Høydal M, Rognmo Ø, Nordhaug D.

Eur J Cardiothorac Surg. 2012 Jun;41(6):1377-83. doi: 10.1093/ejcts/ezr201. Epub 2011 Dec 23.

PMID:
22219475
[PubMed - indexed for MEDLINE]
19.

Succinylcholine does not worsen bupivacaine-induced cardiotoxicity in pentobarbital-anaesthetized dogs.

de La Coussaye JE, Bassoul BP, Albat B, Peray PA, Gagnol JP, Eledjam JJ, Sassine A.

Can J Anaesth. 1992 Feb;39(2):192-7.

PMID:
1544204
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk