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Items: 1 to 20 of 72

1.

Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cells.

Kroiss M, Reuss M, Kühner D, Johanssen S, Beyer M, Zink M, Hartmann MF, Dhir V, Wudy SA, Arlt W, Sbiera S, Allolio B, Fassnacht M.

Front Endocrinol (Lausanne). 2011 Sep 9;2:27. doi: 10.3389/fendo.2011.00027. eCollection 2011.

2.

Inhibition of epithelial growth factor receptor can play an important role in reducing cell growth and survival in adrenocortical tumors.

Gagliano T, Gentilin E, Tagliati F, Benfini K, Di Pasquale C, Feo C, Falletta S, Riva E, degli Uberti E, Zatelli MC.

Biochem Pharmacol. 2015 Dec 15;98(4):639-48. doi: 10.1016/j.bcp.2015.10.012. Epub 2015 Oct 17.

PMID:
26484875
3.

Mitotane exhibits dual effects on steroidogenic enzymes gene transcription under basal and cAMP-stimulating microenvironments in NCI-H295 cells.

Lin CW, Chang YH, Pu HF.

Toxicology. 2012 Aug 16;298(1-3):14-23. doi: 10.1016/j.tox.2012.04.007. Epub 2012 Apr 23.

PMID:
22546480
4.

The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells.

De Martino MC, van Koetsveld PM, Feelders RA, Sprij-Mooij D, Waaijers M, Lamberts SW, de Herder WW, Colao A, Pivonello R, Hofland LJ.

Endocr Relat Cancer. 2012 May 24;19(3):351-64. doi: 10.1530/ERC-11-0270. Print 2012 Jun.

5.

Leukemia inhibitory factor as a regulator of steroidogenesis in human NCI-H295R adrenocortical cells.

Mikhaylova IV, Jääskeläinen T, Jääskeläinen J, Palvimo JJ, Voutilainen R.

J Endocrinol. 2008 Dec;199(3):435-44. doi: 10.1677/JOE-08-0377. Epub 2008 Sep 16.

6.

Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis.

Leal LF, Bueno AC, Gomes DC, Abduch R, de Castro M, Antonini SR.

Oncotarget. 2015 Dec 15;6(40):43016-32. doi: 10.18632/oncotarget.5513.

7.

Interferon-β is a potent inhibitor of cell growth and cortisol production in vitro and sensitizes human adrenocortical carcinoma cells to mitotane.

van Koetsveld PM, Vitale G, Feelders RA, Waaijers M, Sprij-Mooij DM, de Krijger RR, Speel EJ, Hofland J, Lamberts SW, de Herder WW, Hofland LJ.

Endocr Relat Cancer. 2013 May 30;20(3):443-54. doi: 10.1530/ERC-12-0217. Print 2013 Jun.

8.

Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.

Mariniello B, Rosato A, Zuccolotto G, Rubin B, Cicala MV, Finco I, Iacobone M, Frigo AC, Fassina A, Pezzani R, Mantero F.

Endocr Relat Cancer. 2012 Jul 22;19(4):527-39. doi: 10.1530/ERC-11-0337. Print 2012 Aug.

9.
10.

Carriers for type II 3beta-hydroxysteroid dehydrogenase (HSD3B2) deficiency can only be identified by HSD3B2 genotype study and not by hormone test.

Pang S, Carbunaru G, Haider A, Copeland KC, Chang YT, Lutfallah C, Mason JI.

Clin Endocrinol (Oxf). 2003 Mar;58(3):323-31.

PMID:
12608938
11.

Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth.

van Koetsveld PM, Vitale G, de Herder WW, Feelders RA, van der Wansem K, Waaijers M, van Eijck CH, Speel EJ, Croze E, van der Lely AJ, Lamberts SW, Hofland LJ.

J Clin Endocrinol Metab. 2006 Nov;91(11):4537-43. Epub 2006 Aug 15.

PMID:
16912135
12.

Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the low-density lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells.

Martin G, Pilon A, Albert C, Vallé M, Hum DW, Fruchart JC, Najib J, Clavey V, Staels B.

Eur J Biochem. 1999 Apr;261(2):481-91.

13.

Hypocretin/orexin increases the expression of steroidogenic enzymes in human adrenocortical NCI H295R cells.

Wenzel J, Grabinski N, Knopp CA, Dendorfer A, Ramanjaneya M, Randeva HS, Ehrhart-Bornstein M, Dominiak P, Jöhren O.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1601-9. doi: 10.1152/ajpregu.91034.2008. Epub 2009 Sep 30.

14.

Inhibition of Src tyrosine kinase stimulates adrenal androgen production.

Sirianni R, Carr BR, Andò S, Rainey WE.

J Mol Endocrinol. 2003 Jun;30(3):287-99.

15.

The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. implications for the control of adrenal functional zonation.

Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR, Rainey WE.

J Biol Chem. 2004 Sep 3;279(36):37622-30. Epub 2004 Jun 18.

16.

Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.

Kodera Y, Katanasaka Y, Kitamura Y, Tsuda H, Nishio K, Tamura T, Koizumi F.

Breast Cancer Res. 2011 Jun 21;13(3):R66. doi: 10.1186/bcr2903.

17.

Strategic combination therapy overcomes tyrosine kinase coactivation in adrenocortical carcinoma.

Lin CI, Whang EE, Moalem J, Ruan DT.

Surgery. 2012 Dec;152(6):1045-50. doi: 10.1016/j.surg.2012.08.035. Epub 2012 Oct 25.

PMID:
23102636
18.

Interleukins 1α and 1β as regulators of steroidogenesis in human NCI-H295R adrenocortical cells.

Tkachenko IV, Jääskeläinen T, Jääskeläinen J, Palvimo JJ, Voutilainen R.

Steroids. 2011 Sep-Oct;76(10-11):1103-15. doi: 10.1016/j.steroids.2011.04.018. Epub 2011 May 8.

PMID:
21600230
19.

Etomidate unmasks intraadrenal regulation of steroidogenesis and proliferation in adrenal cortical cell lines.

Hahner S, Stürmer A, Fassnacht M, Hartmann RW, Schewe K, Cochran S, Zink M, Schirbel A, Allolio B.

Horm Metab Res. 2010 Jun;42(7):528-34. doi: 10.1055/s-0030-1249629. Epub 2010 Mar 29.

PMID:
20352599
20.

Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer.

Wu CL, Ping SY, Yu CP, Yu DS.

Kaohsiung J Med Sci. 2012 Apr;28(4):194-203. doi: 10.1016/j.kjms.2011.06.020. Epub 2011 Sep 25.

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