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Results: 1 to 20 of 181

1.

Lipid nanoparticles for hepatic delivery of small interfering RNA.

Yu B, Hsu SH, Zhou C, Wang X, Terp MC, Wu Y, Teng L, Mao Y, Wang F, Xue W, Jacob ST, Ghoshal K, Lee RJ, Lee LJ.

Biomaterials. 2012 Sep;33(25):5924-34. doi: 10.1016/j.biomaterials.2012.05.002. Epub 2012 May 29.

PMID:
22652024
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations.

Wang X, Yu B, Ren W, Mo X, Zhou C, He H, Jia H, Wang L, Jacob ST, Lee RJ, Ghoshal K, Lee LJ.

J Control Release. 2013 Dec 28;172(3):690-8. doi: 10.1016/j.jconrel.2013.09.027. Epub 2013 Oct 8.

PMID:
24121065
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Quantitation of physiological and biochemical barriers to siRNA liver delivery via lipid nanoparticle platform.

Xu Y, Ou M, Keough E, Roberts J, Koeplinger K, Lyman M, Fauty S, Carlini E, Stern M, Zhang R, Yeh S, Mahan E, Wang Y, Slaughter D, Gindy M, Raab C, Thompson C, Hochman J.

Mol Pharm. 2014 May 5;11(5):1424-34. doi: 10.1021/mp400584h. Epub 2014 Apr 1.

PMID:
24588618
[PubMed - indexed for MEDLINE]
4.

Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.

Basha G, Novobrantseva TI, Rosin N, Tam YY, Hafez IM, Wong MK, Sugo T, Ruda VM, Qin J, Klebanov B, Ciufolini M, Akinc A, Tam YK, Hope MJ, Cullis PR.

Mol Ther. 2011 Dec;19(12):2186-200. doi: 10.1038/mt.2011.190. Epub 2011 Oct 4.

PMID:
21971424
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer.

Chen Y, Bathula SR, Li J, Huang L.

J Biol Chem. 2010 Jul 16;285(29):22639-50. doi: 10.1074/jbc.M110.125906. Epub 2010 May 11.

PMID:
20460382
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L.

Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13.

PMID:
20628357
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery.

Zhang Y, Arrington L, Boardman D, Davis J, Xu Y, DiFelice K, Stirdivant S, Wang W, Budzik B, Bawiec J, Deng J, Beutner G, Seifried D, Stanton M, Gindy M, Leone A.

J Control Release. 2014 Jan 28;174:7-14. doi: 10.1016/j.jconrel.2013.11.006. Epub 2013 Nov 12.

PMID:
24240015
[PubMed - indexed for MEDLINE]
8.

Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges.

Gomes-da-Silva LC, Fonseca NA, Moura V, Pedroso de Lima MC, Simões S, Moreira JN.

Acc Chem Res. 2012 Jul 17;45(7):1163-71. doi: 10.1021/ar300048p. Epub 2012 May 8.

PMID:
22568781
[PubMed - indexed for MEDLINE]
9.

Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity.

Konca YU, Kirshenbaum K, Zuckermann RN.

Int J Nanomedicine. 2014 May 10;9:2271-85. doi: 10.2147/IJN.S57449. eCollection 2014.

PMID:
24872690
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes.

Bao Y, Jin Y, Chivukula P, Zhang J, Liu Y, Liu J, Clamme JP, Mahato RI, Ng D, Ying W, Wang Y, Yu L.

Pharm Res. 2013 Feb;30(2):342-51. doi: 10.1007/s11095-012-0874-6. Epub 2012 Sep 15.

PMID:
22983644
[PubMed - indexed for MEDLINE]
11.

A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy.

Ding Y, Wang W, Feng M, Wang Y, Zhou J, Ding X, Zhou X, Liu C, Wang R, Zhang Q.

Biomaterials. 2012 Dec;33(34):8893-905. doi: 10.1016/j.biomaterials.2012.08.057. Epub 2012 Sep 12.

PMID:
22979990
[PubMed - indexed for MEDLINE]
12.

Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.

Jayaraman M, Ansell SM, Mui BL, Tam YK, Chen J, Du X, Butler D, Eltepu L, Matsuda S, Narayanannair JK, Rajeev KG, Hafez IM, Akinc A, Maier MA, Tracy MA, Cullis PR, Madden TD, Manoharan M, Hope MJ.

Angew Chem Int Ed Engl. 2012 Aug 20;51(34):8529-33. doi: 10.1002/anie.201203263. Epub 2012 Jul 10.

PMID:
22782619
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Galactose-modified cationic liposomes as a liver-targeting delivery system for small interfering RNA.

Sonoke S, Ueda T, Fujiwara K, Kuwabara K, Yano J.

Biol Pharm Bull. 2011;34(8):1338-42.

PMID:
21804229
[PubMed - indexed for MEDLINE]
Free Article
14.

Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA.

Lin PJ, Tam YY, Hafez I, Sandhu A, Chen S, Ciufolini MA, Nabi IR, Cullis PR.

Nanomedicine. 2013 Feb;9(2):233-46. doi: 10.1016/j.nano.2012.05.019. Epub 2012 Jun 12.

PMID:
22698807
[PubMed - indexed for MEDLINE]
15.

Single-step assembly of cationic lipid-polymer hybrid nanoparticles for systemic delivery of siRNA.

Yang XZ, Dou S, Wang YC, Long HY, Xiong MH, Mao CQ, Yao YD, Wang J.

ACS Nano. 2012 Jun 26;6(6):4955-65. doi: 10.1021/nn300500u. Epub 2012 Jun 5.

PMID:
22646867
[PubMed - indexed for MEDLINE]
16.

Polypeptide cationic micelles mediated co-delivery of docetaxel and siRNA for synergistic tumor therapy.

Zheng C, Zheng M, Gong P, Deng J, Yi H, Zhang P, Zhang Y, Liu P, Ma Y, Cai L.

Biomaterials. 2013 Apr;34(13):3431-8. doi: 10.1016/j.biomaterials.2013.01.053. Epub 2013 Jan 31.

PMID:
23375952
[PubMed - indexed for MEDLINE]
17.

N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver.

Wang HX, Xiong MH, Wang YC, Zhu J, Wang J.

J Control Release. 2013 Mar 10;166(2):106-14. doi: 10.1016/j.jconrel.2012.12.017. Epub 2012 Dec 20.

PMID:
23266452
[PubMed - indexed for MEDLINE]
18.

Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA.

Chang RS, Suh MS, Kim S, Shim G, Lee S, Han SS, Lee KE, Jeon H, Choi HG, Choi Y, Kim CW, Oh YK.

Biomaterials. 2011 Dec;32(36):9785-95. doi: 10.1016/j.biomaterials.2011.09.017. Epub 2011 Sep 19.

PMID:
21937102
[PubMed - indexed for MEDLINE]
19.

Cell penetrating peptide-mediated systemic siRNA delivery to the liver.

Hayashi Y, Yamauchi J, Khalil IA, Kajimoto K, Akita H, Harashima H.

Int J Pharm. 2011 Oct 31;419(1-2):308-13. doi: 10.1016/j.ijpharm.2011.07.038. Epub 2011 Jul 30.

PMID:
21827843
[PubMed - indexed for MEDLINE]
20.

Cationic lipid-coated gold nanoparticles as efficient and non-cytotoxic intracellular siRNA delivery vehicles.

Kong WH, Bae KH, Jo SD, Kim JS, Park TG.

Pharm Res. 2012 Feb;29(2):362-74. doi: 10.1007/s11095-011-0554-y. Epub 2011 Aug 13.

PMID:
21842305
[PubMed - indexed for MEDLINE]
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