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Items: 1 to 20 of 74

1.

Low levels of human HIP14 are sufficient to rescue neuropathological, behavioural, and enzymatic defects due to loss of murine HIP14 in Hip14-/- mice.

Young FB, Franciosi S, Spreeuw A, Deng Y, Sanders S, Tam NC, Huang K, Singaraja RR, Zhang W, Bissada N, Kay C, Hayden MR.

PLoS One. 2012;7(5):e36315. doi: 10.1371/journal.pone.0036315. Epub 2012 May 23.

2.

Altered palmitoylation and neuropathological deficits in mice lacking HIP14.

Singaraja RR, Huang K, Sanders SS, Milnerwood AJ, Hines R, Lerch JP, Franciosi S, Drisdel RC, Vaid K, Young FB, Doty C, Wan J, Bissada N, Henkelman RM, Green WN, Davis NG, Raymond LA, Hayden MR.

Hum Mol Genet. 2011 Oct 15;20(20):3899-909. doi: 10.1093/hmg/ddr308. Epub 2011 Jul 20.

3.

Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease.

Sutton LM, Sanders SS, Butland SL, Singaraja RR, Franciosi S, Southwell AL, Doty CN, Schmidt ME, Mui KK, Kovalik V, Young FB, Zhang W, Hayden MR.

Hum Mol Genet. 2013 Feb 1;22(3):452-65. doi: 10.1093/hmg/dds441. Epub 2012 Oct 16.

4.

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

Huang K, Sanders SS, Kang R, Carroll JB, Sutton L, Wan J, Singaraja R, Young FB, Liu L, El-Husseini A, Davis NG, Hayden MR.

Hum Mol Genet. 2011 Sep 1;20(17):3356-65. doi: 10.1093/hmg/ddr242. Epub 2011 Jun 2.

5.

Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L.

Sanders SS, Mui KK, Sutton LM, Hayden MR.

PLoS One. 2014 Feb 28;9(2):e90669. doi: 10.1371/journal.pone.0090669. eCollection 2014.

6.

Aberrant palmitoylation in Huntington disease.

Sanders SS, Hayden MR.

Biochem Soc Trans. 2015 Apr;43(2):205-10. doi: 10.1042/BST20140242. Review.

PMID:
25849918
7.

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.

Butland SL, Sanders SS, Schmidt ME, Riechers SP, Lin DT, Martin DD, Vaid K, Graham RK, Singaraja RR, Wanker EE, Conibear E, Hayden MR.

Hum Mol Genet. 2014 Aug 1;23(15):4142-60. doi: 10.1093/hmg/ddu137. Epub 2014 Apr 4.

8.

Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.

Goytain A, Hines RM, Quamme GA.

J Biol Chem. 2008 Nov 28;283(48):33365-74. doi: 10.1074/jbc.M801469200. Epub 2008 Sep 15.

9.

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.

Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR.

Hum Mol Genet. 2002 Nov 1;11(23):2815-28.

10.

Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.

Sanders SS, Hou J, Sutton LM, Garside VC, Mui KK, Singaraja RR, Hayden MR, Hoodless PA.

Dev Biol. 2015 Jan 15;397(2):257-66. doi: 10.1016/j.ydbio.2014.11.018. Epub 2014 Dec 3.

11.

Putting proteins in their place: palmitoylation in Huntington disease and other neuropsychiatric diseases.

Young FB, Butland SL, Sanders SS, Sutton LM, Hayden MR.

Prog Neurobiol. 2012 May;97(2):220-38. doi: 10.1016/j.pneurobio.2011.11.002. Epub 2011 Dec 7. Review.

PMID:
22155432
12.

Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles.

Ohyama T, Verstreken P, Ly CV, Rosenmund T, Rajan A, Tien AC, Haueter C, Schulze KL, Bellen HJ.

J Cell Biol. 2007 Dec 31;179(7):1481-96. Epub 2007 Dec 24.

13.

Dysregulated striatal neuronal processing and impaired motor behavior in mice lacking huntingtin interacting protein 14 (HIP14).

Estrada-Sánchez AM, Barton SJ, Burroughs CL, Doyle AR, Rebec GV.

PLoS One. 2013 Dec 23;8(12):e84537. doi: 10.1371/journal.pone.0084537. eCollection 2013.

14.

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A.

Neuron. 2004 Dec 16;44(6):977-86.

16.

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity.

Huang K, Sanders S, Singaraja R, Orban P, Cijsouw T, Arstikaitis P, Yanai A, Hayden MR, El-Husseini A.

FASEB J. 2009 Aug;23(8):2605-15. doi: 10.1096/fj.08-127399. Epub 2009 Mar 19.

17.

Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function.

Yanai A, Huang K, Kang R, Singaraja RR, Arstikaitis P, Gan L, Orban PC, Mullard A, Cowan CM, Raymond LA, Drisdel RC, Green WN, Ravikumar B, Rubinsztein DC, El-Husseini A, Hayden MR.

Nat Neurosci. 2006 Jun;9(6):824-31. Epub 2006 May 14.

18.

Memory and synaptic deficits in Hip14/DHHC17 knockout mice.

Milnerwood AJ, Parsons MP, Young FB, Singaraja RR, Franciosi S, Volta M, Bergeron S, Hayden MR, Raymond LA.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20296-301. doi: 10.1073/pnas.1222384110. Epub 2013 Nov 25.

19.

Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.

Ducker CE, Stettler EM, French KJ, Upson JJ, Smith CD.

Oncogene. 2004 Dec 9;23(57):9230-7.

20.

Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype.

Hodgson JG, Smith DJ, McCutcheon K, Koide HB, Nishiyama K, Dinulos MB, Stevens ME, Bissada N, Nasir J, Kanazawa I, Disteche CM, Rubin EM, Hayden MR.

Hum Mol Genet. 1996 Dec;5(12):1875-85.

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