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Results: 1 to 20 of 113

1.

Proteomic analysis of covalent modifications of tubulins by isothiocyanates.

Xiao Z, Mi L, Chung FL, Veenstra TD.

J Nutr. 2012 Jul;142(7):1377S-81S. doi: 10.3945/jn.111.152041. Epub 2012 May 30.

PMID:
22649267
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis.

Mi L, Xiao Z, Hood BL, Dakshanamurthy S, Wang X, Govind S, Conrads TP, Veenstra TD, Chung FL.

J Biol Chem. 2008 Aug 8;283(32):22136-46. doi: 10.1074/jbc.M802330200. Epub 2008 Jun 3.

PMID:
18524779
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Identification of potential protein targets of isothiocyanates by proteomics.

Mi L, Hood BL, Stewart NA, Xiao Z, Govind S, Wang X, Conrads TP, Veenstra TD, Chung FL.

Chem Res Toxicol. 2011 Oct 17;24(10):1735-43. doi: 10.1021/tx2002806. Epub 2011 Aug 26.

PMID:
21838287
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes.

Mi L, Gan N, Cheema A, Dakshanamurthy S, Wang X, Yang DC, Chung FL.

J Biol Chem. 2009 Jun 19;284(25):17039-51. doi: 10.1074/jbc.M901789200. Epub 2009 Apr 1.

PMID:
19339240
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.

Mi L, Wang X, Govind S, Hood BL, Veenstra TD, Conrads TP, Saha DT, Goldman R, Chung FL.

Cancer Res. 2007 Jul 1;67(13):6409-16.

PMID:
17616701
[PubMed - indexed for MEDLINE]
Free Article
6.

Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.

Mi L, Chung FL.

Nutr Cancer. 2008;60 Suppl 1:12-20. doi: 10.1080/01635580802381287.

PMID:
19003576
[PubMed - indexed for MEDLINE]
8.

Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.

Mi L, Gan N, Chung FL.

Carcinogenesis. 2011 Feb;32(2):216-23. doi: 10.1093/carcin/bgq242. Epub 2010 Nov 25.

PMID:
21109604
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.

Wu X, Zhu Y, Yan H, Liu B, Li Y, Zhou Q, Xu K.

BMC Cancer. 2010 Jun 9;10:269. doi: 10.1186/1471-2407-10-269.

PMID:
20534110
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Effects of phenylethyl isothiocyanate and its metabolite on cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells.

Hwang ES, Lee HJ.

Int J Food Sci Nutr. 2010 May;61(3):324-36. doi: 10.3109/09637481003639092.

PMID:
20402549
[PubMed - indexed for MEDLINE]
11.

Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation.

Duangmano S, Sae-Lim P, Suksamrarn A, Domann FE, Patmasiriwat P.

BMC Complement Altern Med. 2012 Oct 12;12:185. doi: 10.1186/1472-6882-12-185.

PMID:
23062075
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines.

Jakubikova J, Bao Y, Sedlak J.

Anticancer Res. 2005 Sep-Oct;25(5):3375-86.

PMID:
16101152
[PubMed - indexed for MEDLINE]
Free Article
13.

New biomarkers for monitoring the levels of isothiocyanates in humans.

Kumar A, Sabbioni G.

Chem Res Toxicol. 2010 Apr 19;23(4):756-65. doi: 10.1021/tx900393t.

PMID:
20131755
[PubMed - indexed for MEDLINE]
14.

Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.

Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.

J Orthop Res. 2011 Aug;29(8):1199-209. doi: 10.1002/jor.21350. Epub 2011 Mar 4.

PMID:
21374707
[PubMed - indexed for MEDLINE]
15.

Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.

Yan H, Zhu Y, Liu B, Wu H, Li Y, Wu X, Zhou Q, Xu K.

Br J Nutr. 2011 Dec;106(12):1779-91. doi: 10.1017/S0007114511002315. Epub 2011 Jun 23.

PMID:
21733335
[PubMed - indexed for MEDLINE]
16.

A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models.

Chen JY, Tang YA, Li WS, Chiou YC, Shieh JM, Wang YC.

PLoS One. 2013 Apr 30;8(4):e62082. doi: 10.1371/journal.pone.0062082. Print 2013.

PMID:
23646116
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study.

Syed Alwi SS, Cavell BE, Telang U, Morris ME, Parry BM, Packham G.

Br J Nutr. 2010 Nov;104(9):1288-96. doi: 10.1017/S0007114510002217. Epub 2010 Jun 15.

PMID:
20546646
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Selected isothiocyanates rapidly induce growth inhibition of cancer cells.

Zhang Y, Tang L, Gonzalez V.

Mol Cancer Ther. 2003 Oct;2(10):1045-52.

PMID:
14578469
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Sulforaphane inhibits human MCF-7 mammary cancer cell mitotic progression and tubulin polymerization.

Jackson SJ, Singletary KW.

J Nutr. 2004 Sep;134(9):2229-36.

PMID:
15333709
[PubMed - indexed for MEDLINE]
Free Article

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