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Results: 1 to 20 of 109

1.

A histopathologic pattern of centrilobular hepatocyte injury suggests 6-mercaptopurine-induced hepatotoxicity in patients with inflammatory bowel disease.

Masia R, Pratt DS, Misdraji J.

Arch Pathol Lab Med. 2012 Jun;136(6):618-22. doi: 10.5858/arpa.2011-0214-OA.

PMID:
22646267
[PubMed - indexed for MEDLINE]
2.

Incidence, risk factors and clinical course of thiopurine-induced liver injury in patients with inflammatory bowel disease.

Bastida G, Nos P, Aguas M, Beltrán B, Rubín A, Dasí F, Ponce J.

Aliment Pharmacol Ther. 2005 Nov 1;22(9):775-82.

PMID:
16225485
[PubMed - indexed for MEDLINE]
Free Article
3.

Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease.

Ansari A, Elliott T, Baburajan B, Mayhead P, O'Donohue J, Chocair P, Sanderson J, Duley J.

Aliment Pharmacol Ther. 2008 Sep 15;28(6):734-41.

PMID:
19145729
[PubMed - indexed for MEDLINE]
4.

[Nodular regenerative hyperplasia as a complication of thiopurine treatment in a patient with inflammatory bowel disease].

Cohen-Ezra O, Avni Y, Morgenstern S, Ben-Ari Z.

Harefuah. 2012 Dec;151(12):675-8, 721. Hebrew.

PMID:
23330258
[PubMed - indexed for MEDLINE]
5.

Assessment of non-cirrhotic portal hypertension associated with thiopurine therapy in inflammatory bowel disease.

Calabrese E, Hanauer SB.

J Crohns Colitis. 2011 Feb;5(1):48-53. doi: 10.1016/j.crohns.2010.08.007. Epub 2010 Oct 18. Review.

PMID:
21272804
[PubMed - indexed for MEDLINE]
6.

Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease.

Geller SA, Dubinsky MC, Poordad FF, Vasiliauskas EA, Cohen AH, Abreu MT, Tran T, Martin P, Vierling JM, Targan SR.

Am J Surg Pathol. 2004 Sep;28(9):1204-11.

PMID:
15316320
[PubMed - indexed for MEDLINE]
7.

Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol.

Leong RW, Gearry RB, Sparrow MP.

Expert Opin Drug Saf. 2008 Sep;7(5):607-16. doi: 10.1517/14740338.7.5.607 . Review.

PMID:
18759713
[PubMed - indexed for MEDLINE]
8.

Adverse events of thiopurine immunomodulators in patients with inflammatory bowel disease.

López-Martín C, Chaparro M, Espinosa L, Bejerano A, Maté J, Gisbert JP.

Gastroenterol Hepatol. 2011 Jun-Jul;34(6):385-92. doi: 10.1016/j.gastrohep.2011.03.023. Epub 2011 May 25.

PMID:
21616565
[PubMed - indexed for MEDLINE]
9.

Thiopurine metabolite monitoring in paediatric inflammatory bowel disease.

Ooi CY, Bohane TD, Lee D, Naidoo D, Day AS.

Aliment Pharmacol Ther. 2007 Apr 15;25(8):941-7.

PMID:
17402998
[PubMed - indexed for MEDLINE]
Free Article
10.

Histopathology of liver biopsies from a thiopurine-naïve inflammatory bowel disease cohort: prevalence of nodular regenerative hyperplasia.

De Boer NK, Tuynman H, Bloemena E, Westerga J, Van Der Peet DL, Mulder CJ, Cuesta MA, Meuwissen SG, Van Nieuwkerk CM, Van Bodegraven AA.

Scand J Gastroenterol. 2008;43(5):604-8. doi: 10.1080/00365520701800266.

PMID:
18415755
[PubMed - indexed for MEDLINE]
11.

Toxicity of 6-thioguanine: no hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?

Gilissen LP, Derijks LJ, Driessen A, Bos LP, Hooymans PM, Stockbrügger RW, Engels LG.

Dig Liver Dis. 2007 Feb;39(2):156-9. Epub 2006 Dec 26.

PMID:
17188950
[PubMed - indexed for MEDLINE]
12.

Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease.

Hindorf U, Johansson M, Eriksson A, Kvifors E, Almer SH.

Aliment Pharmacol Ther. 2009 Mar 15;29(6):654-61. doi: 10.1111/j.1365-2036.2008.03925.x. Epub 2008 Dec 22.

PMID:
19183142
[PubMed - indexed for MEDLINE]
13.

Liver injury in inflammatory bowel disease: long-term follow-up study of 786 patients.

Gisbert JP, Luna M, González-Lama Y, Pousa ID, Velasco M, Moreno-Otero R, Maté J.

Inflamm Bowel Dis. 2007 Sep;13(9):1106-14.

PMID:
17455203
[PubMed - indexed for MEDLINE]
14.

Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients.

Shaye OA, Yadegari M, Abreu MT, Poordad F, Simon K, Martin P, Papadakis KA, Ippoliti A, Vasiliauskas E, Tran TT.

Am J Gastroenterol. 2007 Nov;102(11):2488-94. Epub 2007 Aug 31.

PMID:
17764490
[PubMed - indexed for MEDLINE]
15.

Hepatotoxicity associated with 6-methyl mercaptopurine formation during azathioprine and 6-mercaptopurine therapy does not occur on the short-term during 6-thioguanine therapy in IBD treatment.

van Asseldonk DP, Seinen ML, de Boer NK, van Bodegraven AA, Mulder CJ.

J Crohns Colitis. 2012 Feb;6(1):95-101. doi: 10.1016/j.crohns.2011.07.009.

PMID:
22261533
[PubMed - indexed for MEDLINE]
16.

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA.

Gastroenterology. 2002 Apr;122(4):904-15.

PMID:
11910342
[PubMed - indexed for MEDLINE]
17.

Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review.

Gisbert JP, González-Lama Y, Maté J.

Am J Gastroenterol. 2007 Jul;102(7):1518-27. Epub 2007 Mar 27. Review.

PMID:
17391318
[PubMed - indexed for MEDLINE]
18.

[Thiopurine-induced hyperammonaemic encephalopathy in a patient with Crohn's disease].

Laish I, Pomeranz I, Kitay-Cohen Y, Konikof F.

Harefuah. 2012 Dec;151(12):692-5, 720. Hebrew.

PMID:
23330262
[PubMed - indexed for MEDLINE]
19.

Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease.

Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, Théorêt Y, Seidman EG.

Gastroenterology. 2000 Apr;118(4):705-13.

PMID:
10734022
[PubMed - indexed for MEDLINE]
20.

6-Thioguanine-related hepatotoxicity in patients with inflammatory bowel disease: dose or level dependent?

Derijks LJ, Gilissen LP, de Boer NK, Mulder CJ.

J Hepatol. 2006 Apr;44(4):821-2. Epub 2006 Jan 24. No abstract available.

PMID:
16487623
[PubMed - indexed for MEDLINE]

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